RecruitingPhase 4NCT06269770

Tapentadol vs Tramadol in Total Knee Arthroplasty

Multimodal Analgesia in TKA. The Role of Tapentadol

Sponsor

University of Thessaly

Enrollment

96 participants

Start Date

May 1, 2023

Study Type

INTERVENTIONAL

Conditions

Compare the effectiveness of tapentadol and tramadol as part of a multimodal analgesia treatment for Total Knee Replacement (TKR).

Min Age: 18 YearsMax Age: 80 Years

Patient refusal
Cognitive disfunction
Severe psychiatric disease
Under medication with MAO inhibitors, tricyclic antidepressants, serotonin reuptake inhibitors
Not speaking Greek
Known allergy to the study drugs
Contraindications for any of the study drugs
Chronic renal failure (GFR \< 50 ml/h)
Liver failure
Known regular use or misuse of opioids
Pregnant women
Patients undergoing general anesthesia

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DRUGTapentadol

Add tapentadol, for effective pain management in a multimodal setting during TKR.

DRUGTramadol

Add tramadol, for effective pain management in a multimodal setting during TKR.

University Hospital Of Larissa

Larissa, Thessaly, Greece

View Full Details on ClinicalTrials.gov

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NCT06269770