RecruitingPhase 4NCT06269770
Tapentadol vs Tramadol in Total Knee Arthroplasty
Multimodal Analgesia in TKA. The Role of Tapentadol
Sponsor
University of Thessaly
Enrollment
96 participants
Start Date
May 1, 2023
Study Type
INTERVENTIONAL
Conditions
Summary
Compare the effectiveness of tapentadol and tramadol as part of a multimodal analgesia treatment for Total Knee Replacement (TKR).
Eligibility
Min Age: 18 YearsMax Age: 80 Years
Inclusion Criteria2
- Patients for elective TKR
- ASA PS I - III
Exclusion Criteria12
- Patient refusal
- Cognitive disfunction
- Severe psychiatric disease
- Under medication with MAO inhibitors, tricyclic antidepressants, serotonin reuptake inhibitors
- Not speaking Greek
- Known allergy to the study drugs
- Contraindications for any of the study drugs
- Chronic renal failure (GFR < 50 ml/h)
- Liver failure
- Known regular use or misuse of opioids
- Pregnant women
- Patients undergoing general anesthesia
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Interventions
DRUGTapentadol
Add tapentadol, for effective pain management in a multimodal setting during TKR.
DRUGTramadol
Add tramadol, for effective pain management in a multimodal setting during TKR.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06269770
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