Cigarettes Clinical Trials

9 recruitingLast updated: June 21, 2026

There are 9 actively recruiting cigarettes clinical trials across 3 countries. Studies span Not Applicable, Early Phase 1. Top locations include Buffalo, New York, United States, Chapel Hill, North Carolina, United States, Durham, North Carolina, United States. Updated daily from ClinicalTrials.gov.


Cigarettes Trials at a Glance

9 actively recruiting trials for cigarettes are listed on ClinicalTrialsFinder across 6 cities in 3 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Buffalo, Chapel Hill, and Durham. Lead sponsors running cigarettes studies include State University of New York at Buffalo, Rowan University, and Ottawa Heart Institute Research Corporation.

Browse cigarettes trials by phase

Treatments under study

About Cigarettes Clinical Trials

Looking for clinical trials for Cigarettes? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cigarettes trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cigarettes clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting
Not Applicable

Pilot Study of Communication for Dual Users of Cigarettes and E-cigarettes

Tobacco ProductsCigarettesElectronic Cigarettes
UNC Lineberger Comprehensive Cancer Center90 enrolled1 locationNCT07599462
Recruiting
Not Applicable

The INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency Departments

Nicotine Dependence, CigarettesNicotine Withdrawal
Ottawa Heart Institute Research Corporation1,208 enrolled4 locationsNCT04163081
Recruiting
Early Phase 1

Neurobehavioral Mechanisms Linking Childhood Adversity to Increased Risk for Smoking

Nicotine Dependence, CigarettesAdverse Childhood Experiences
Duke University150 enrolled1 locationNCT05665465
Recruiting
Not Applicable

Vaping and Smoking Withdrawal Project

Acute Abstinence From Cigarettes vs E-cigarettes (ENDS)
State University of New York at Buffalo370 enrolled1 locationNCT05772845
Recruiting
Not Applicable

Vaping and Smoking Project in People With Schizophrenia

Acute Abstinence From Cigarettes vs E-cigarettes (ENDS)
State University of New York at Buffalo64 enrolled1 locationNCT06944847
Recruiting
Not Applicable

Quitting Matters Human Immunodeficiency Virus Hybrid Trial

Smoking CessationCancer PreventionHuman Immunodeficiency Virus (HIV)+4 more
Wake Forest University Health Sciences314 enrolled1 locationNCT06883097
Recruiting
Not Applicable

Cessation of Dual Use of Cigarettes and E-cigarettes During Pregnancy

Gestational Weight GainDual Use of Cigarettes and E-cigarettesBirth-weight-for-gestational-age z Score
State University of New York at Buffalo45 enrolled1 locationNCT07124702
Recruiting
Not Applicable

Re-Connect Application for Smoking Cessation

Smoking CessationAcceptability of Health CareNicotine Dependence, Cigarettes
Rowan University82 enrolled1 locationNCT05224154
Recruiting

Quitting Using Incentives Trial for a HEaLthy Pregnancy (QUIT-HELP)

Smoking cigarettes in pregnancy
University of Adelaide460 enrolled2 locationsACTRN12623000922673