CNS Tumor Clinical Trials

4 recruiting

Frequently Asked Questions

Common questions about CNS Tumor clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 111 of 11 trials

Recruiting
Phase 1

ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

Central Nervous System TumorGlioblastomaCNS Tumor+5 more
Sabine Mueller, MD, PhD208 enrolled6 locationsNCT04732065
Recruiting
Phase 1

A Study of Avutometinib for People With Solid Tumor Cancers

Solid TumorSolid Tumor, AdultNeuroblastoma+12 more
Memorial Sloan Kettering Cancer Center23 enrolled2 locationsNCT06104488
Recruiting

Self-administered Remote Neurological Examination Using Mobile Application in Patients With Brain Tumors

Artificial Intelligence (AI)Digital HealthGlioma+1 more
Tata Memorial Centre600 enrolled1 locationNCT07236840
Recruiting
Not Applicable

Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors

Brain CancerGliomasRecurrent CNS Tumors+3 more
National Cancer Institute (NCI)80 enrolled1 locationNCT07374692
Recruiting
Phase 1

Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors

Solid TumorLymphomaGIST+5 more
ITM Solucin GmbH20 enrolled2 locationsNCT06441331
Recruiting
Phase 1Phase 2

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

LymphomaMetastatic Solid TumorsLocally Advanced Solid Tumors+1 more
Turning Point Therapeutics, Inc.75 enrolled68 locationsNCT04094610
Recruiting
Phase 4

68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.

ParagangliomaMeningiomaEsthesioneuroblastoma+4 more
Weill Medical College of Cornell University200 enrolled1 locationNCT04081701
Recruiting
Phase 1Phase 2

Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System Tumors

GliomaCNS Tumor, AdultCNS Tumor, Childhood
Centre Leon Berard70 enrolled11 locationsNCT07243470
Recruiting

Characterizing Sleep Among Long-term Survivors of Childhood Cancer

Solid TumorALL, AdultCNS Tumor
St. Jude Children's Research Hospital120 enrolled1 locationNCT05480904
Recruiting
Not Applicable

Proton Versus Photon Radiotherapy in Adults With Primary Brain Tumors

MeningiomaDiffuse GliomaPituitary Adenoma+2 more
Tata Memorial Centre156 enrolled1 locationNCT06831461
Recruiting

Artificial Intelligence in CNS Radiation Oncology

CNS Tumor
Tata Memorial Centre6,000 enrolled1 locationNCT06036394