CNS Tumor Clinical Trials

8 recruiting

CNS Tumor Trials at a Glance

19 actively recruiting trials for cns tumor are listed on ClinicalTrialsFinder across 6 cities in 22 countries. The largest study group is Phase 1 with 8 trials, with the heaviest enrollment activity in New York, Paris, and Madrid. Lead sponsors running cns tumor studies include Tata Memorial Centre, St. Jude Children's Research Hospital, and Hoffmann-La Roche.

Browse cns tumor trials by phase

Treatments under study

About CNS Tumor Clinical Trials

Looking for clinical trials for CNS Tumor? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new CNS Tumor trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about CNS Tumor clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 119 of 19 trials

Recruiting
Phase 1

Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors

Solid TumorLymphomaGIST+5 more
ITM Solucin GmbH20 enrolled5 locationsNCT06441331
Recruiting
Phase 1Phase 2

Combination of Tarlatamab and Temozolomide in Patients With Central Nervous System Tumors

GliomaCNS Tumor, AdultCNS Tumor, Childhood
Centre Leon Berard70 enrolled11 locationsNCT07243470
Recruiting
Phase 2

Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors

CNS TumorHigh Grade Glioma
St. Jude Children's Research Hospital52 enrolled4 locationsNCT06528691
Recruiting

Characterizing Sleep Among Long-term Survivors of Childhood Cancer

Solid TumorALL, AdultCNS Tumor
St. Jude Children's Research Hospital120 enrolled1 locationNCT05480904
Recruiting
Phase 1

A Study of PHST001 in Advanced Solid Tumors

Ovarian CancerEndometrial CancerCholangiocarcinoma+2 more
Pheast Therapeutics272 enrolled20 locationsNCT06840886
Recruiting
Phase 1Phase 2

A Study Evaluating the Safety, Pharmacokinetics, and Efficacy of Alectinib in Pediatric Participants With ALK Fusion-Positive Solid or CNS Tumors

ALK Fusion-positive Solid or CNS Tumors
Hoffmann-La Roche42 enrolled33 locationsNCT04774718
Recruiting
Not Applicable

Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors

Brain CancerGliomasRecurrent CNS Tumors+3 more
National Cancer Institute (NCI)80 enrolled1 locationNCT07374692
Recruiting
Phase 1

ONC206 for Treatment of Newly Diagnosed, Recurrent Diffuse Midline Gliomas, and Other Recurrent Malignant CNS Tumors

Central Nervous System TumorGlioblastomaCNS Tumor+5 more
Sabine Mueller, MD, PhD208 enrolled6 locationsNCT04732065
Recruiting
Phase 1

A Study of Avutometinib for People With Solid Tumor Cancers

Solid TumorSolid Tumor, AdultNeuroblastoma+12 more
Memorial Sloan Kettering Cancer Center23 enrolled2 locationsNCT06104488
Recruiting

Self-administered Remote Neurological Examination Using Mobile Application in Patients With Brain Tumors

Artificial Intelligence (AI)Digital HealthGlioma+1 more
Tata Memorial Centre600 enrolled1 locationNCT07236840
Recruiting
Phase 2

Antiangiogenic Therapy for Children With Recurrent Medulloblastoma, Ependymoma, ATRT and Rare CNS Tumors

Medulloblastoma RecurrentEpendymoma RecurrentATRT Recurrent+1 more
Medical University of Vienna232 enrolled22 locationsNCT01356290
Recruiting
Phase 1Phase 2

A Study of Repotrectinib in Pediatric and Young Adult Subjects Harboring ALK, ROS1, OR NTRK1-3 Alterations

LymphomaMetastatic Solid TumorsLocally Advanced Solid Tumors+1 more
Turning Point Therapeutics, Inc.75 enrolled68 locationsNCT04094610
Recruiting
Phase 4

68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors.

ParagangliomaMeningiomaEsthesioneuroblastoma+4 more
Weill Medical College of Cornell University200 enrolled1 locationNCT04081701
Recruiting
Not Applicable

Proton Versus Photon Radiotherapy in Adults With Primary Brain Tumors

MeningiomaDiffuse GliomaPituitary Adenoma+2 more
Tata Memorial Centre156 enrolled1 locationNCT06831461
Recruiting

Artificial Intelligence in CNS Radiation Oncology

CNS Tumor
Tata Memorial Centre6,000 enrolled1 locationNCT06036394
Recruiting
Not Applicable

Whole Body Metabolism in Children Before and After Treatment of CNS Tumor

CNS Tumor, Childhood
Rigshospitalet, Denmark30 enrolled1 locationNCT06380387
Recruiting
Phase 1Phase 2

INFORM2 Study Uses Nivolumab and Entinostat in Children and Adolescents With High-risk Refractory Malignancies

Solid TumorCNS Tumor
University Hospital Heidelberg91 enrolled14 locationsNCT03838042
Recruiting

Development of Asian Consortium for Data Collection and Clinical Trial of CNS Tumors

CNS TumorCNS GerminomaAsian Consortium
National Cancer Center, Korea400 enrolled1 locationNCT05982691
Recruiting
Phase 2

The Efficacy of WVI in Patients With Localized Basal Ganglia Intracranial Germ Cell Tumors

Intracranial Germ Cell CNS Tumor, Childhood
Beijing Tiantan Hospital150 enrolled1 locationNCT05124951