Phase 3 Colorectal, Cancer Clinical Trials
27 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 27 trials
Recruiting
Phase 3
Botensilimab + Balstilimab vs Best Supportive Care as Therapy in Chemo-refractory, Unresectable, Colorectal Adenocarcinoma
Colorectal, Cancer
Canadian Cancer Trials Group834 enrolled12 locationsNCT07152821
Recruiting
Phase 3
Bevacizumab Plus mFOLFOXIRI as First-line Treatment for Patients With Unresectable Metastatic Colorectal Cancer
Colorectal, Cancer
Yanhong Deng528 enrolled1 locationNCT04230187
Recruiting
Phase 3
Study on Aspirin Versus Placebo in Resected Colon Cancer With PI3K Mutation Stage III or II High Risk
Colorectal, Cancer
University Hospital, Rouen264 enrolled1 locationNCT02945033
Recruiting
Phase 3
Adjuvant FOLFIRI Based-chemotherapy After Resection of CLM Responding to Preoperative FOLFIRI
Colorectal, CancerColorectal Liver Metastases
Assistance Publique - Hôpitaux de Paris254 enrolled1 locationNCT06501482
Recruiting
Phase 3
FOLFOXIRI Plus Bevacizumab With or Without Atezolizumab as 1st Line Treatment of pMMR and IS IC-High Metastatic Colorectal Cancer Patients.
Colorectal, Cancer
Gruppo Oncologico del Nord-Ovest238 enrolled24 locationsNCT06733038
Recruiting
Phase 3
Post-resection/Ablation Chemotherapy in Patients With Metastatic Colorectal Cancer (FIRE-9 - PORT / AIO-KRK-0418)
Colorectal, Cancer
Dominik Paul Modest507 enrolled79 locationsNCT05008809
Recruiting
Phase 3
Study in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaB
Colorectal, CancerMetastatic Colorectal CancerRAS Mutation
Azienda USL Reggio Emilia - IRCCS280 enrolled4 locationsNCT04776655
Recruiting
Phase 2Phase 3
Fruquintinib With or Without HAI-FOLFOX for Refractory Colorectal Cancer
Colorectal, Cancer
Sun Yat-sen University84 enrolled1 locationNCT06441565
Recruiting
Phase 3
Efficacy of Hyperthermic Intraperitoneal Chemotherapy
Colorectal, CancerPeritoneal Metastases
Uppsala University213 enrolled5 locationsNCT04861558
Recruiting
Phase 2Phase 3
Neoadjuvant Serplulimab & Bevacizumab With FOLFOX vs. FOLFOX Alone in RAS/BRAF WT, pMMR/MSS CRC Patients
Colorectal, CancerLiver Metastases
Sun Yat-sen University156 enrolled1 locationNCT06280495
Recruiting
Phase 3
SBRT + PD-1 Monoclonal Antibody in Unresectable Colorectal Liver Metastases
Colorectal, CancerLiver Metastases
Jun Huang24 enrolled1 locationNCT06794086
Recruiting
Phase 3
Conversion Therapy of RAS/BRAF Wild-Type Colorectal Cancer Patients With Initially Unresectable Liver Metastases
Colorectal, CancerLiver Metastases
Fudan University508 enrolled1 locationNCT04687631
Recruiting
Phase 3
A Study of Tucidinostat in Combination With Sintilimab and Bevacizumab in MSS/pMMR Colorectal Cancer Patients
Colorectal, Cancer
Chipscreen Biosciences, Ltd.430 enrolled1 locationNCT06497985
Recruiting
Phase 3
Adjuvant PD-1 Blockade for High-risk Stage-II DMMR/MSI-H Colorectal Cancer
Colorectal, CancerMicrosatellite Instability High
Sun Yat-sen University180 enrolled1 locationNCT06520683
Recruiting
Phase 3
Combination of IV Ascorbic Acid and Adebrelimab in Metastatic Colorectal Cancer
Colorectal, CancerVitamin CGLUT3
Fudan University400 enrolled1 locationNCT04516681
Recruiting
Phase 3
Reducing Inflammatory Syndrome in Surgery - Colorectal (RISIS-CR) Trial
Colorectal, Cancer
National University Hospital, Singapore80 enrolled4 locationsNCT06646809
Recruiting
Phase 3
DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer
Colorectal, CancerMetastatic CancerOlder Patients+1 more
Leiden University Medical Center587 enrolled36 locationsNCT06275958
Recruiting
Phase 3
Intraoperative Indocyanine Green Fluorescence Angiography in Colorectal Surgery to Prevent Anastomotic Leakage
Colorectal, Cancer
Centre Hospitalier Universitaire de Besancon1,010 enrolled32 locationsNCT05168839
Recruiting
Phase 2Phase 3
COLDFIRE-III Trial: Efficacy of Irreversible Electroporation and Stereotactic Body Radiotherapy for Perivascular and Peribiliary Colorectal Liver Metastases
Colorectal, CancerLiver MetastasesUnresectable Solid Tumor+1 more
Amsterdam UMC, location VUmc78 enrolled1 locationNCT06185556
Recruiting
Phase 3
Cadonilimab (AK104) Combined With Chemotherapy and Bevacizumab as First-line Treatment for RAS Mutated or Right Sided-metastatic MSS Colorectal Cancer
Colorectal, Cancer
Caigang Liu30 enrolled1 locationNCT06566755