Phase 2 Colorectal, Cancer Clinical Trials
125 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 125 trials
Recruiting
Phase 1Phase 2
A Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid Tumors
Colorectal, CancerPancreatic CancerMetastatic Solid Tumor+5 more
Frontier Medicines Corporation403 enrolled26 locationsNCT06244771
Recruiting
Phase 2
A Phase II Study of SHR-8068 Injection in Combination With Anti-tumor Therapies in Colorectal Cancer
Colorectal, Cancer
Suzhou Suncadia Biopharmaceuticals Co., Ltd.200 enrolled1 locationNCT07071714
Recruiting
Phase 2
A Randomized Phase 2 Trial of Fruquintinib and TAS-102 as Compared to Fruquintinib in Patients With Refractory Advanced/Metastatic Colorectal Cancer
Colorectal, Cancer
Criterium, Inc.120 enrolled9 locationsNCT06992258
Recruiting
Phase 2
A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (mCRC)
Colorectal, CancerColon CancerRectal Cancer+1 more
SCRI Development Innovations, LLC60 enrolled14 locationsNCT07011576
Recruiting
Phase 2
Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer
Colorectal, Cancer
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins44 enrolled1 locationNCT06205836
Recruiting
Phase 1Phase 2
Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases
Colorectal, CancerResectable SarcomaMetastatic Malignant Neoplasm in the Lung+3 more
Roswell Park Cancer Institute99 enrolled1 locationNCT03965234
Recruiting
Phase 1Phase 2
Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
Colorectal, CancerPancreatic Ductal AdenocarcinomaMetastatic Pancreatic Ductal Adenocarcinoma+3 more
Revolution Medicines, Inc.1,130 enrolled32 locationsNCT06445062
Recruiting
Phase 2
A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
Colorectal, Cancer
AbbVie140 enrolled41 locationsNCT07023289
Recruiting
Phase 2
Pre-operative Targeted Treatments in Molecularly Selected Resectable Colorectal Cancer (UNICORN)
Colorectal, CancerResectable Colorectal Carcinoma
Gruppo Oncologico del Nord-Ovest197 enrolled1 locationNCT05845450
Recruiting
Phase 1Phase 2
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
Breast CancerTriple-Negative Breast CancerColorectal, Cancer+26 more
PMV Pharmaceuticals, Inc300 enrolled76 locationsNCT04585750
Recruiting
Phase 1Phase 2
A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors
Colorectal, CancerNon-small Cell Lung CancerPancreatic Ductal Adenocarcinoma+2 more
Verastem, Inc.295 enrolled12 locationsNCT07020221
Recruiting
Phase 2
A Study of YL202 in Patients With Advanced Solid Tumors
Colorectal, CancerCervical CancerNon-small Cell Lung Cancer+1 more
MediLink Therapeutics (Suzhou) Co., Ltd.100 enrolled1 locationNCT07202364
Recruiting
Phase 2
Effect of Perioperative Lidocaine or High-Dose Dexamethasone on Immune Response in Colon Cancer Surgery (PILDI Study)
Colorectal, CancerColon CancerPerioperative Immune Response
Institute of Oncology Ljubljana100 enrolled1 locationNCT07432399
Recruiting
Phase 2
TAS-102 With or Without Celecoxib in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy
Colorectal, Cancer
M.D. Anderson Cancer Center25 enrolled1 locationNCT05343013
Recruiting
Phase 2
Telehealth Intervention for Ostomy Self-Management
Colorectal, CancerBladder Cancer
City of Hope Medical Center150 enrolled1 locationNCT06528990
Recruiting
Phase 1Phase 2
Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread
Metastatic Breast CancerColorectal, CancerEsophageal Adenocarcinoma+2 more
Boehringer Ingelheim768 enrolled103 locationsNCT06324357
Recruiting
Phase 1Phase 2
Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis
Colorectal, CancerEsophageal CancerGastric Cancer+18 more
Neonc Technologies, Inc.134 enrolled6 locationsNCT06047379
Recruiting
Phase 2
A Phase 2 Trial of Fruquintinib and Tislelizumab in ctDNA-defined Minimal Residual Disease in Colorectal Cancer After Completion of Adjuvant Chemotherapy
Colorectal, CancerMinimal Residual DiseasectDNA+3 more
M.D. Anderson Cancer Center20 enrolled1 locationNCT07136077
Recruiting
Phase 2
Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial
Breast CancerLiver CancerColorectal, Cancer+7 more
University of California, Irvine24 enrolled1 locationNCT07447050
Recruiting
Phase 1Phase 2
A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours
Colorectal, CancerMelanomaHead and Neck Squamous Cell Carcinoma+2 more
Ipsen220 enrolled12 locationsNCT06305247