Phase 4 Complication Clinical Trials

51 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 51 trials

Recruiting
Phase 4

The Effect of Different Types of Mouthwash on Extraction Sockets' Healing

Quality of LifePostoperative ComplicationsExtraction Socket Healing
University of Jordan100 enrolled1 locationNCT06587880
Recruiting
Phase 4

SWIFT - SWIss Factor XIII Trial in PPH

Postpartum ComplicationCoagulation DisorderPostpartum Hemorrhage+2 more
Christian Haslinger988 enrolled9 locationsNCT06481995
Recruiting
Phase 4

PeRiOperative Medicine Platform Trial

Quality of LifeAnaesthesiaSurgical Site Infection After Major Surgery+2 more
Monash University7,800 enrolled2 locationsNCT07186634
Recruiting
Phase 4

Inhaling Penehyclidine to Prevent Perioperative Respiratory Adverse Events in Children at Risk Undergoing Sevoflurane Anesthesia

Perioperative Respiratory Adverse EventsHigh-RiskRespiratory Hypersensitivity+2 more
Sun Yat-sen University204 enrolled2 locationsNCT06624696
Recruiting
Phase 4

A Comparison of Remimazolam Besylate and Propofol Sedation in Patients Undergoing Colonoscopic Polypectomy

Colonic PolypSedation Complication
Clinical Hospital Centre Zagreb90 enrolled1 locationNCT07456111
Recruiting
Phase 4

A Randomized, Placebo-controlled Trial of DAPAgliflozin (DAPA) for Cardiovascular Risk Reduction in the Postpartum Period of Hypertensive Pregnancies (HP)

Cardiovascular ComplicationPre-EclampsiaGestational Hypertension+2 more
University of Michigan200 enrolled1 locationNCT06785116
Recruiting
Phase 4

A Study to Investigate of the Effects of Opioid Exposure on the Ability of the Diaphragm Muscle

Respiratory Function LossRespiratory Complication
Mayo Clinic69 enrolled1 locationNCT05856136
Recruiting
Phase 4

Risk of Acute Complications With Rocuronium vs Cisatracurium in Patients With Chronic Kidney Disease

Post-operative Pulmonary ComplicationsGeneral AnesthesiaNeuromuscular Blockade
The University of Texas Medical Branch, Galveston490 enrolled1 locationNCT07203287
Recruiting
Phase 4

Treatment With Aspirin After Preeclampsia: TAP Trial

Cardiovascular DiseasesHypertensionPregnancy Complications+8 more
Malamo Countouris60 enrolled1 locationNCT06281665
Recruiting
Phase 4

Pasteurised Donor Human Milk Supplementation for Term Babies

neonatal intensive care unitMental Health IssueHospital Length of Stay+4 more
The University of Queensland1,444 enrolled4 locationsNCT06993103
Recruiting
Phase 4

LDA and LMWH vs LDA Alone in High-risk Patients for Preeclampsia Prevention

Pregnancy ComplicationsPreeclampsiaGestational Hypertension+3 more
Alexandra Hospital, Athens, Greece100 enrolled1 locationNCT07361679
Recruiting
Phase 4

Sedation Efficacy and Safety of Remazolam Besylate in Ventilated Surgical Critically Ill Patients

SurgeryMechanical Ventilation ComplicationCritical Illness+3 more
Beijing Shijitan Hospital, Capital Medical University306 enrolled1 locationNCT06575530
Recruiting
Phase 4

Single Dose of Antenatal Corticosteroids for Pregnancies at Risk of Preterm Delivery (SNACS)

Pregnancy ComplicationsPremature BirthObstetric Labor, Premature+2 more
McMaster University3,254 enrolled25 locationsNCT05114096
Recruiting
Phase 4

Semaglutide Treatment for Hyperglycaemia After Renal Transplantation

DiabetesHyperglycemiaRenal Transplant Complication Primary Non-Function
Rigshospitalet, Denmark104 enrolled1 locationNCT05702931
Recruiting
Phase 4

Strategic Help With Immunoglobulin to Enhance Protect Against Late Disease (CMV)

Liver Transplant; ComplicationsKidney Transplant; ComplicationsCytomegalovirus+2 more
Camille N. Kotton, MD80 enrolled2 locationsNCT06958796
Recruiting
Phase 4

Azithromycin and Ampicillin for Late PPROM

Premature BirthAntibiotic ProphylaxisPrematurity+3 more
Sheba Medical Center311 enrolled1 locationNCT07183462
Recruiting
Phase 4

A Randomized Trial of Lenient Versus Strict Arm Instruction Post Cardiac Device Surgery

Post-Op Complication
Ottawa Heart Institute Research Corporation6,300 enrolled1 locationNCT04915261
Recruiting
Phase 4

The Effect of Continuous Glucose Monitoring in Surgical Patients With Diabetes.

Diabetes MellitusPerioperative ComplicationDysglycemia
Christian S. Meyhoff200 enrolled3 locationsNCT06314061
Recruiting
Phase 4

Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin Graft

BurnsSkin Graft Complications
University of Kansas Medical Center62 enrolled1 locationNCT06379724
Recruiting
Phase 4

Continuous Infusion of Norepinephrine vs Phenylephrine During Spinal Anesthesia for Cesarean Section (INPEACE)

HypotensionCesarean Section Complications
Hassan II University140 enrolled2 locationsNCT06248593