Phase 3 Congenital Clinical Trials
18 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–18 of 18 trials
Recruiting
Phase 3
A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia
Congenital Adrenal HyperplasiaClassic Congenital Adrenal Hyperplasia
Crinetics Pharmaceuticals Inc.150 enrolled26 locationsNCT07144163
Recruiting
Phase 2Phase 3
A Study in Pediatric Participants With Congenital Adrenal Hyperplasia (Balance-CAH)
Congenital Adrenal HyperplasiaClassic Congenital Adrenal Hyperplasia
Crinetics Pharmaceuticals Inc.153 enrolled32 locationsNCT07159841
Recruiting
Phase 3
A Study to Assess How Effective and Safe NVD003 is for Treating Patients With Congenital Pseudarthrosis of the Tibia.
Congenital Pseudarthrosis of Tibia
Novadip Biosciences12 enrolled7 locationsNCT07112443
Recruiting
Phase 3
Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)
Sensation DisordersLeber Congenital AmaurosisBlindness+3 more
Laboratoires Thea32 enrolled14 locationsNCT06891443
Recruiting
Phase 3
18F-DOPA II - PET Imaging Optimization
Neuroendocrine TumorsBrain TumorNeuroblastoma+3 more
University of Alberta800 enrolled1 locationNCT04706910
Recruiting
Phase 3
Spinal Morphine or Intravenous Lidocaine in Robot-assisted Upper Urologic Surgery
Ureter CancerRenal CancerOther Specified Disorders of Kidney and Ureter+5 more
Hans Bahlmann220 enrolled3 locationsNCT06349668
Recruiting
Phase 3
Recombinant Single-chain Factor VIII (rVIII-SingleChain) in Chinese Participants With Hemophilia A Previously Treated With FVIII Products
Congenital Hemophilia A
CSL Behring60 enrolled20 locationsNCT06738485
Recruiting
Phase 3
A Study to Learn About the Safety and Efficacy of the Drug Oleogel-S10 in Japanese Patients With Epidermolysis Bullosa
Skin DiseasesEpidermolysis BullosaConnective Tissue Disease+7 more
Chiesi Farmaceutici S.p.A.6 enrolled6 locationsNCT06917690
Recruiting
Phase 3
Efficacy of Atenativ in Patients With Congenital Antithrombin Deficiency Undergoing Surgery or Delivery
Congenital Antithrombin Deficiency
Octapharma38 enrolled30 locationsNCT04918173
Not Yet Recruiting
Phase 3
Evaluating cefixime for the prevention of congenital syphilis: a single-dose pharmacokinetic study (Study 1 of 3)
Congenital Syphilis
World Health Organization64 enrolled1 locationACTRN12625001180404
Recruiting
Phase 3
Effect of Sacubitril-Valsartan on Cardiac Structure and Function
Congenital Heart Disease
Mayo Clinic45 enrolled1 locationNCT06693674
Recruiting
Phase 3
Safety and Efficacy of FETO in CDH Phase III
Pulmonary HypertensionCongenital Diaphragmatic HerniaPulmonary Hypoplasia
Children's Hospital Medical Center, Cincinnati75 enrolled1 locationNCT07187206
Recruiting
Phase 3
NO During CPB in Neonates to Reduce Risk of AKI
SurgeryAKICHD - Congenital Heart Disease
Children's Hospital Medical Center, Cincinnati40 enrolled1 locationNCT04216927
Recruiting
Phase 2Phase 3
Human Penile Allotransplantation
Wounds and InjuriesAmputationAmputation, Traumatic+6 more
Johns Hopkins University60 enrolled1 locationNCT02395497
Recruiting
Phase 2Phase 3
Fetal Cerebrovascular Autoregulation in Congenital Heart Disease and Association With Neonatal Neurobehavior
HypoxiaNeurodevelopmental DisordersCongenital Heart Disease in Children+1 more
University of Utah150 enrolled5 locationsNCT05767385
Recruiting
Phase 2Phase 3
Safety and Efficacy of Tideglusib in Congenital or Childhood Onset Myotonic Dystrophy
Congenital Myotonic Dystrophy
AMO Pharma Limited76 enrolled14 locationsNCT05004129
Recruiting
Phase 3
Cerebrum and Cardiac Protection With Allopurinol in Neonates With Critical Congenital Heart Disease Requiring Cardiac Surgery With Cardiopulmonary Bypass
Congenital Heart Disease in ChildrenNeuroprotection
dr. M.J.N.L. Benders236 enrolled4 locationsNCT04217421
Completed
Phase 2Phase 3
Upper limb - Baby Early Action-observation Training: Randomised trial of the effect of infant action observation training on the early development of hand reaching and grasping in healthy infants and in infants with early brain injury.
Venous infarctionAsymmetric brain lesionsCongenital hemiplegia+1 more
Professor Roslyn Boyd72 enrolled1 locationACTRN12611000991910