Consciousness Clinical Trials

64 recruitingLast updated: July 26, 2026

There are 64 actively recruiting consciousness clinical trials across 11 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4, Early Phase 1. Top locations include Boston, Massachusetts, United States, Guangzhou, Guangdong, China, Shanghai, Shanghai Municipality, China. Updated daily from ClinicalTrials.gov.


Consciousness Trials at a Glance

64 actively recruiting trials for consciousness are listed on ClinicalTrialsFinder across 6 cities in 11 countries. The largest study group is Not Applicable with 30 trials, with the heaviest enrollment activity in Boston, Guangzhou, and Shanghai. Lead sponsors running consciousness studies include Beijing Tiantan Hospital, Massachusetts General Hospital, and University of Liege.

Browse consciousness trials by phase

Treatments under study

About Consciousness Clinical Trials

Looking for clinical trials for Consciousness? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Consciousness trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Consciousness clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 64 trials

Recruiting
Not Applicable

Vagus Nerve Stimulation in Patients in Comatose State

Traumatic Brain InjurySevere Traumatic Brain InjuryDisorders of Consciousness Due to Severe Brain Injury+1 more
Sima Mofakham10 enrolled1 locationNCT07719595
Recruiting

Spontaneous Eye Blinking in Disorders of Consciousness

Disorders of Consciousness
Fondazione Don Carlo Gnocchi ETS70 enrolled8 locationsNCT06323031
Recruiting

China Research for Severe Spontaneous Intracerebral Hemorrhage(CRISIH)

Emergency surgeryComplicationsDisorders of Consciousness+2 more
Beijing Tiantan Hospital2,000 enrolled1 locationNCT05975398
Recruiting
Not Applicable

Assessment of Safety and Feasibility of FUS Next Generation Dome Helmet (NGDH) to Perform Neuromodulation in Patients With Disorders of Consciousness

Disorders of ConsciousnessDisorders of Consciousness Due to Severe Brain Injury
Sunnybrook Health Sciences Centre10 enrolled1 locationNCT07694258
Recruiting

Cerebral Autoregulation, Brain Perfusion, and Neurocognitive Outcomes After Traumatic Brain Injury

TBITBI (Traumatic Brain Injury)Brain Injury Traumatic Severe+2 more
University of Texas Southwestern Medical Center130 enrolled3 locationsNCT06480838
Recruiting
Not Applicable

Combined Whole-brain Structural and Functional MRI for the Prediction of Neurological Recovery After Cardiac Arrest

comaNeurologic DisorderDisorder of Consciousness+1 more
University Hospital, Toulouse263 enrolled1 locationNCT06617377
Recruiting
Early Phase 1

REstoring CONsciousness With NEurostimulation of the Central Thalamus: The RECONNECT Study

Disorders of Consciousness
Samuel Snider, MD2 enrolled1 locationNCT07228286
Recruiting
Not Applicable

Paired Vagus Nerve Stimulation in Mobilization of Patients With Prolonged Disorders of Consciousness

Brain InjuryConsciousness DisordersAltered Level of Consciousness
Icahn School of Medicine at Mount Sinai15 enrolled1 locationNCT06930716
Recruiting
Not Applicable

Promoting Recovery After Brain Injury Using Focused Ultrasound

Consciousness DisordersDisorders of Consciousness Due to Severe Brain Injury
Massachusetts General Hospital36 enrolled2 locationsNCT07277309
Recruiting

fNIRS for Disorders of Consciousness

comaBrain InjuryDisorders of Consciousness+4 more
University of California, Los Angeles55 enrolled1 locationNCT07485361
Recruiting

Recovery Trajectory for Coma and Disorders of Consciousness

Traumatic Brain InjuriescomaDisorders of Consciousness+5 more
University of California, San Francisco2,000 enrolled1 locationNCT07614074
Recruiting

Neurorehabilitation in Patients With Disorders of Consciousness: Multidimensional Ambispective Study on the Impact of Single and Combined Approaches

Disorder of Consciousness
IRCCS Centro Neurolesi Bonino Pulejo140 enrolled1 locationNCT07385508
Recruiting
Not Applicable

Ultrasound Stimulation for Patients in a Disorder of Consciousness

Consciousness DisordersDisorders of Consciousness Due to Severe Brain Injury
University of California, Los Angeles60 enrolled4 locationsNCT06939348
Recruiting
Phase 4

Efficacy and Safety of Cerebrolysin on Prolonged Disorders of Consciousness

Disorder of ConsciousnessHemorrhagic Stroke
Konkuk University Medical Center12 enrolled1 locationNCT04427241
Recruiting
Not Applicable

Effectiveness of tTIs for Improving Consciousness in Patients With DoC

Disorders of ConsciousnessMinimally Conscious StateVegetative State
Zhujiang Hospital136 enrolled1 locationNCT07539740
Recruiting
Not Applicable

Investigation of Mnesic Capacities in Patients With a Disorder of Consciousness

Disorders of Consciousness
Assistance Publique - Hôpitaux de Paris175 enrolled2 locationsNCT06959212
Recruiting
Not Applicable

Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Patients With Disorders of Consciousness

Disorders of Consciousness
Zhujiang Hospital20 enrolled1 locationNCT07284732
Recruiting

Correlating EEG Dynamics With Consciousness Alteration Under Anesthesia

Altered State of ConsciousnessGeneral Anesthetics
Huazhong University of Science and Technology250 enrolled1 locationNCT07410702
Recruiting

Assessment of Consciousness With CRS-R and SECONDs

Disorders of Consciousness Due to Severe Brain InjuryMinimally Conscious StateUnresponsive Wakefulness Syndrome
BDH-Klinik Hessisch Oldendorf110 enrolled1 locationNCT07456020
Recruiting
Not Applicable

Window On the Brain

Disorders of Consciousness
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta100 enrolled4 locationsNCT06693492