Consciousness Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about Consciousness clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 50 trials

Recruiting
Not Applicable

Effect of Transcutaneous Auricular Vagus Nerve Stimulation on Patients With Disorders of Consciousness

Disorders of Consciousness
Zhujiang Hospital20 enrolled1 locationNCT07284732
Recruiting

Correlating EEG Dynamics With Consciousness Alteration Under Anesthesia

Altered State of ConsciousnessGeneral Anesthetics
Huazhong University of Science and Technology250 enrolled1 locationNCT07410702
Recruiting

Assessment of Consciousness With CRS-R and SECONDs

Disorders of Consciousness Due to Severe Brain InjuryMinimally Conscious StateUnresponsive Wakefulness Syndrome
BDH-Klinik Hessisch Oldendorf110 enrolled1 locationNCT07456020
Recruiting
Not Applicable

Promoting Recovery After Brain Injury Using Focused Ultrasound

Consciousness DisordersDisorders of Consciousness Due to Severe Brain Injury
Massachusetts General Hospital36 enrolled2 locationsNCT07277309
Recruiting
Not Applicable

Window On the Brain

Disorders of Consciousness
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta100 enrolled4 locationsNCT06693492
Recruiting
Not Applicable

REcovery From DEXmedetomidine-induced Unconsciousness

AnesthesiaHealthyConsciousness, Level Altered
Massachusetts General Hospital12 enrolled1 locationNCT06003127
Recruiting

Micro-expressions in Patients With Prolonged Disorders of Consciousness

Consciousness Disorders
First Affiliated Hospital of Zhejiang University200 enrolled1 locationNCT06088628
Recruiting

Micro-movements in Patients With Prolonged Disorders of Consciousness

Consciousness Disorders
First Affiliated Hospital of Zhejiang University179 enrolled1 locationNCT06406413
Recruiting
Not Applicable

Study on the Effectiveness and Safety of Temporal Interference Stimulation in Treating Patients With Severe Consciousness Disorders

Disorder of ConsciousnessTemporal Interference Stimulation
Huashan Hospital20 enrolled2 locationsNCT06896279
Recruiting
Not Applicable

Robotic vs. Traditional Verticalization in Patients With Severe Acquired Brain Injury: a Randomized Controlled Trial

Disorder of ConsciousnessAcquired Brain Injury
Anna Estraneo118 enrolled6 locationsNCT06469983
Recruiting
Early Phase 1

REstoring CONsciousness With NEurostimulation of the Central Thalamus: The RECONNECT Study

Disorders of Consciousness
Samuel Snider, MD2 enrolled1 locationNCT07228286
Recruiting
Not Applicable

Ultrasound Stimulation for Patients in a Disorder of Consciousness

Consciousness DisordersDisorders of Consciousness Due to Severe Brain Injury
University of California, Los Angeles60 enrolled4 locationsNCT06939348
Recruiting

Diagnosis Value of Interoceptive EEG Indicators by Rectal Stimulation in DoC

Disorders of Consciousness
YiLin Zhao45 enrolled2 locationsNCT07208942
Recruiting

Spontaneous Eye Blinking in Disorders of Consciousness

Disorders of Consciousness
Fondazione Don Carlo Gnocchi Onlus70 enrolled8 locationsNCT06323031
Recruiting

Screening Emotions in Adolescents at the Hospital for mTBI

Brain InjuriesBrain Injury Traumatic MildHead Injury Trauma+4 more
University of California, Davis2,592 enrolled6 locationsNCT06370520
Recruiting
Not Applicable

Effectiveness of Music Therapy on Level of Consciousness

Traumatic Brain InjuryNeurologic DisorderDisorder of Consciousness
BDH-Klinik Hessisch Oldendorf66 enrolled1 locationNCT04442971
Recruiting

Prognostic Factors to Regain Consciousness

Traumatic Brain InjuryStrokeNeurologic Disorder+1 more
BDH-Klinik Hessisch Oldendorf130 enrolled1 locationNCT04445649
Recruiting
Not Applicable

Paired Vagus Nerve Stimulation in Mobilization of Patients With Prolonged Disorders of Consciousness

Brain InjuryConsciousness DisordersAltered Level of Consciousness
Icahn School of Medicine at Mount Sinai15 enrolled1 locationNCT06930716
Recruiting

An Ethical Approach to Detecting Covert Consciousness

Disorder of Consciousness
Massachusetts General Hospital70 enrolled1 locationNCT05010265
Recruiting

Emotional and Neutral Sounds for Neurophysiological Prognostic Assessment of Critically Ill Patients With a Disorder of Consciousness

Disorder of Consciousness
Assistance Publique - Hôpitaux de Paris114 enrolled2 locationsNCT05740735