Phase 3 Control Clinical Trials
15 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–15 of 15 trials
Recruiting
Phase 3
A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout
Uncontrolled Gout
Amgen270 enrolled25 locationsNCT07388498
Recruiting
Phase 3
A Study Assessing the Effect of Dupilumab on Inducing Clinical Remission in Asthma
Asthma Control
Université de Sherbrooke150 enrolled5 locationsNCT07309614
Recruiting
Phase 3
Intensification of Blood Pressure Lowering Therapeutics Based on Diuretics Versus Usual Management for Uncontrolled Hypertension IN Patients With Moderate to Severe Chronic Kidney Disease
Chronic Kidney Disease(CKD)Uncontrolled Hypertension
University Hospital, Tours720 enrolled40 locationsNCT05732727
Recruiting
Phase 3
Pain Control Alternatives in Pediatric Patients With Distal Radius Fractures
Pain ControlDistal Radius Fracture ReductionPediatric Fractures
State University of New York at Buffalo50 enrolled1 locationNCT07120763
Recruiting
Phase 3
Efficacy and Safety of Semaglutide Injection Vs WEGOVY® in Chinese Obese Patients
Obesity Control
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.460 enrolled1 locationNCT07036172
Recruiting
Phase 2Phase 3
Perioperative Analgesia Modes in Minimally Invasive Esophagectomy
Esophageal CancerPerioperative AnalgesiaNSAIDs+2 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences102 enrolled1 locationNCT05504265
Terminated
Phase 3Phase 4
Is ketamine a useful addition for the management of acute pain in patients where opiates alone have failed to provide adequate analgesia?
Difficult to control acute pain
Bundaberg Base Hospital65 enrolled1 locationACTRN12615001151527
Completed
Phase 2Phase 3
Effects of Glucagon-Like Peptide-1 (GLP-1) administration on gastric emptying during periods of hyperglycaemia in healthy volunteers.
Glycaemic control and gastric emptying
Dr Mark Plummer15 enrolled1 locationACTRN12613001384741
Withdrawn
Phase 2Phase 3
A randomised, double-blind, double-dummy study of the effects of insulin and glucagon-like peptide-1 on glycaemia, gastric emptying, gastro-oesophageal reflux and mesenteric blood flow in the critically ill
Gastric emptyingGlycaemic controlCritical Illness
Dr Yasmine Ali Abdelhamid50 enrolled1 locationACTRN12613001383752
Completed
Phase 3Phase 4
low level laser and osteoarthritis
aim of this randomized placebo-controlled single-blind clinical trial was to evaluate the short-term efficacy of LLLT on pain alleviation and functional performance in the patients with chronic knee OA
Mohammed taher ahmed omar42 enrolled1 locationACTRN12612000615886
Completed
Phase 2Phase 3
Clinical trial of a Chinese herbal medicine for the treatment of prediabetes and mild diabetes
Mild diabetes defined as those with diabetes diagnosed within 5 yrs of enrolment in the clinical trial, diet and exercise controlled and not taking any medications.Impaired glucose tolerance defined as having a fasting blood glucose <7.8 mmol and a 2 hour post prandial blood glucose >7.8 but <11.00
Xiyuan Hospital100 enrolled1 locationACTRN12612000128897
Recruiting
Phase 2Phase 3
Evaluation of Captopril and Nifedipine in Treatment of Hypertension in Children with Post-streptoccal Acute Glomerulonephritis with Hypertension- A Randomized Control Trial
Control of Blood Pressure in Patients with Post-sterptococcal Acute Glomerulonephritis (PSAGN)Renal profiles in patients with Post-streptococcal Acute Glomerulonephritis (PSAGN)
Universiti Sains Malaysia (USM)40 enrolled1 locationACTRN12611000778987
Active
Phase 3
A study to evaluate whether increased codeine levels are seen when both codeine and ketamine are given in small doses to well volunteers.
The possibility that ketamine,an anaesthetic medication but which is also used at much lower doses, to help try and control severe chronic nerve pain, may increase the effective blood levels of opioids such as codeine or morphine that are often given in conjunction with ketamine.This study is looking at drug metabolism not pain management or anaesthesiology
Flinders University- Department of Clinical Pharmacology10 enrolled1 locationACTRN12610000283077
Recruiting
Phase 3
A large-scale trial testing the intensity of CYTOreductive therapy to prevent cardiovascular events In patients with Polycythemia Vera (PV)
To assess the benefit/risk profile of cytoreductive therapy with phlebotomy and/or hydroxyurea (HU) aimed at maintaining hematocrit (HCT) < 45% Vs. maintaining HCT in the range of 45-50% in patients with PV treated at the best of recommended therapies (e.g., low dose of aspirin when indicated and adequated control of standard cardiovascular risk factors)
Consorzio Mario Negri Sud1,000 enrolled1 locationACTRN12609000046202
Recruiting
Phase 3
Isocapnic intermittent hypoxia and endothelial dysfunction
Healthy control subjects
NHMRC10 enrolled1 locationACTRN12605000280606