Phase 3 Cornea Clinical Trials

7 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 17 of 7 trials

Recruiting
Phase 3

An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCED

Persistent Corneal Epithelial Defect
Dompé Farmaceutici S.p.A150 enrolled77 locationsNCT07519902
Recruiting
Phase 3

Fungal Ulcer Treatment Augmented With Natamycin and Cyclosporine A

corneal ulcerFungal Keratitis
University of California, San Francisco150 enrolled2 locationsNCT06658002
Recruiting
Phase 3

AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

Corneal EdemaCorneal Endothelial DysfunctionFuchs Endothelial Corneal Dysfunction+1 more
Aurion Biotech120 enrolled12 locationsNCT07368959
Recruiting
Phase 3

Comparison of Epi-ON Corneal Collagen Crosslinking Performed Using an 18-Minute UVA Exposure vs. a 24-Minute UVA Exposure on Eyes With Ectatic Corneal Diseases

KeratoconusEctasia of CorneaPellucid Marginal Corneal Degeneration+1 more
Woolfson Eye Institute485 enrolled12 locationsNCT07124910
Recruiting
Phase 2Phase 3

Comparison of Standard vs. Accelerated Corneal Crosslinking

KeratoconusEctasia Corneal
Price Vision Group510 enrolled1 locationNCT03922542
Recruiting
Phase 2Phase 3

Corneal Crosslinking for Treatment of Corneal Neovascularization

Corneal Neovascularization
Price Vision Group62 enrolled1 locationNCT04787471
Recruiting
Phase 3

Effects of Topical Insulin on Corneal Epithelium Healing After Corneal Crosslinking in Patients With Keratoconus

Wound HealEye DiseasesKeratoconus+1 more
University of Campinas, Brazil36 enrolled1 locationNCT06601101