Phase 2 Crohn Disease Clinical Trials

20 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 20 trials

Recruiting
Phase 2Phase 3

A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

Crohn Disease
Janssen Research & Development, LLC1,092 enrolled324 locationsNCT07196722
Recruiting
Phase 2

Impact Of The Gut Microbiota On Host Cells Energy Metabolism in Health And In Inflammatory Bowel Disease

Crohn DiseaseUlcerative Colitis (UC)IBD
Assistance Publique - Hôpitaux de Paris45 enrolled1 locationNCT07300553
Recruiting
Phase 1Phase 2

Stem Cell Transplantation in Crohn's Disease

Crohn Disease
Cedars-Sinai Medical Center15 enrolled1 locationNCT04224558
Recruiting
Phase 2

HB-adMSCs for the Treatment of Crohn's Disease

Crohn Disease (CD)
Hope Biosciences Research Foundation46 enrolled1 locationNCT07077746
Recruiting
Phase 2

Standardized Microbiota Transplant Therapy in Crohn's Disease

Crohn Disease
University of Minnesota120 enrolled1 locationNCT06631586
Recruiting
Phase 2

Comparison of Quality of Life During a Flare of Crohn's Disease Treated With Prednisolone or aCDED With PEN in Adult Patients

Crohn DiseaseNutrition AssessmentDiet Therapy
University Hospital Tuebingen52 enrolled1 locationNCT06953791
Recruiting
Phase 1Phase 2

Low Dose IL-2 for the Treatment of Crohn's Disease

Crohn Disease
Boston Children's Hospital30 enrolled3 locationsNCT04263831
Recruiting
Phase 1Phase 2

Dose Escalation of Allogeneic Adipose Derived Stroma/Stem Cells for the Treatment of Crohn's Fistula

Crohn Disease
University Hospital, Toulouse9 enrolled1 locationNCT06636032
Recruiting
Phase 2

Safety and Efficacy of Capsule FMT in Treatment-naïve Patients With Newly Diagnosed Chronic Inflammatory Diseases

Rheumatoid ArthritisAnkylosing SpondylitisCrohn Disease+2 more
Odense University Hospital200 enrolled1 locationNCT04924270
Recruiting
Phase 2

Autologous Stem Cell Transplant for Crohn's Disease

Crohn Disease
Aaron Etra50 enrolled1 locationNCT03219359
Recruiting
Phase 2

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

Moderately to Severely Active Crohn Disease
Abivax S.A.212 enrolled149 locationsNCT06456593
Recruiting
Phase 2

Target Engagement of EXL01 in the Prevention of Post-operative Recurrence of Crohn's Disease

Crohn Disease (CD)
Madeleine Bezault80 enrolled12 locationsNCT06925061
Recruiting
Phase 1Phase 2

Pilot and Feasibility Study of 2'-FL as a Dietary Supplement in IBD Patients Receiving Stable Maintenance Anti-TNF Therapy

Inflammatory Bowel DiseasesCrohn DiseaseUlcerative Colitis
Children's Hospital Medical Center, Cincinnati116 enrolled3 locationsNCT03847467
Recruiting
Phase 2

Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease

Crohn Disease (CD)
Washington University School of Medicine60 enrolled3 locationsNCT06976853
Recruiting
Phase 1Phase 2

Fluorescence Imaging of Risankizumab-800CW in Inflammatory Bowel Disease

Ulcerative Colitis (UC)Crohn Disease (CD)
University Medical Center Groningen18 enrolled1 locationNCT06606808
Recruiting
Phase 1Phase 2

Microbial Restoration in Inflammatory Bowel Diseases

Inflammatory Bowel DiseasesCrohn DiseaseMicrobiome+1 more
St Vincent's Hospital Melbourne120 enrolled1 locationNCT04970446
Recruiting
Phase 2Phase 3

Precise Infliximab Exposure and Pharmacodynamic Control

Crohn Disease
Children's Hospital Medical Center, Cincinnati180 enrolled11 locationsNCT05660746
Recruiting
Phase 2

Evaluation of Local Co-administration of Autologous ADIpose Derived Stromal Vascular Fraction With Microfat for Refractory Perianal CROHN's Fistulas.

Crohn Disease
Assistance Publique Hopitaux De Marseille84 enrolled1 locationNCT04010526
Recruiting
Phase 2

FAPi-PET Imaging of in Vivo Fibrosis in Inflammatory Bowel Disease Patients

IBD (Inflammatory Bowel Disease)Ulcerative Colitis (UC)Crohn Disease (CD)
Dalia Lartey20 enrolled1 locationNCT06604260
Recruiting
Phase 1Phase 2

Fluorescence Imaging of Adalimumab-680LT in Inflammatory Bowel Disease

Crohn DiseaseUlcerative Colitis
University Medical Center Groningen21 enrolled1 locationNCT06117423