Cryptogenic Stroke Clinical Trials

7 recruitingLast updated: June 18, 2026

There are 7 actively recruiting cryptogenic stroke clinical trials across 12 countries. Studies span Not Applicable. Top locations include Ahaus, Germany, Bad Nauheim, Germany, Bad Neustadt an der Saale, Germany. Updated daily from ClinicalTrials.gov.


Cryptogenic Stroke Trials at a Glance

7 actively recruiting trials for cryptogenic stroke are listed on ClinicalTrialsFinder across 6 cities in 12 countries. The largest study group is Not Applicable with 6 trials, with the heaviest enrollment activity in Ahaus, Bad Nauheim, and Bad Neustadt an der Saale. Lead sponsors running cryptogenic stroke studies include Encore Medical Inc., Hospital Universitari Vall d'Hebron Research Institute, and Biotronik SE & Co. KG.

Browse cryptogenic stroke trials by phase

Treatments under study

About Cryptogenic Stroke Clinical Trials

Looking for clinical trials for Cryptogenic Stroke? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cryptogenic Stroke trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cryptogenic Stroke clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 17 of 7 trials

Recruiting
Not Applicable

Medical Treatment With or Without Transcatheter Patent Foramen Ovale Closure

Older PatientsCryptogenic StrokeMedical Treatment+2 more
Josep Rodes-Cabau714 enrolled2 locationsNCT05907694
Recruiting
Not Applicable

Early Feasibility Study (EFS) Evaluating Percutaneous Repair of the Atrial Septum With a Novel PFO Occluder: The PROTEA-PFO Study

Cryptogenic StrokePFO - Patent Foramen OvalePFO+2 more
Recross Cardio, Inc.15 enrolled5 locationsNCT07172464
Recruiting

Observation of Clinical Routine Care for Patients With BIOTRONIK Implantable Cardiac Monitors (ICMs)

Atrial FibrillationSyncopeBradycardia+2 more
Biotronik SE & Co. KG1,400 enrolled31 locationsNCT04075084
Recruiting
Not Applicable

Smartwatch and External Holter Monitoring to Detect Atrial Fibrillation in Patients With Cryptogenic Stroke

Paroxysmal Atrial FibrillationCryptogenic Stroke
Hospital Universitari Vall d'Hebron Research Institute100 enrolled1 locationNCT05565781
Recruiting
Not Applicable

Encore PFO Closure Device - The PerFOrm Trial

Cryptogenic StrokePatent foramen ovale
Encore Medical Inc.500 enrolled8 locationsNCT05537753
Recruiting
Not Applicable

Atrial Anomalies Predict Silent Atrial Fibrillation Detected by Implantable Cardiac Monitor in Cryptogenic Stroke

Cardiac Rhythm DisorderParoxysmal Atrial FibrillationLeft Atrial Dilatation+1 more
Parc de Salut Mar100 enrolled1 locationNCT06542770
Recruiting
Not Applicable

Safety and Efficacy of Cera™ Patent Foramen Ovale Occluders.

Cryptogenic StrokePatent foramen ovale
Lifetech Scientific (Shenzhen) Co., Ltd.244 enrolled14 locationsNCT05774288