RecruitingNot ApplicableNCT05565781

Smartwatch and External Holter Monitoring to Detect Atrial Fibrillation in Patients With Cryptogenic Stroke

Impact of Non-invasive Remote Monitoring Via Wearable Technologies for Detection of Atrial Fibrillation in Patients With Cryptogenic Stroke


Sponsor

Hospital Universitari Vall d'Hebron Research Institute

Enrollment

100 participants

Start Date

Mar 28, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Stroke recurrence largely depends on the detection of the cause and the control of vascular risk factors, with occult atrial fibrillation (AF) being one of the most important. Prolonged ambulatory cardiac monitoring is recommended for detecting occult AF. Currently, there are non-invasive monitoring devices such as the textile Holter that have proven to be useful for monitoring for up to 30 days but not longer. Another alternative is smartwatches, although they must be validated for use in the elderly population who have had a stroke.


Eligibility

Min Age: 55 Years

Inclusion Criteria4

  • Age greater to or equal to 55 years
  • Patients with diagnosis of cryptogenic stroke after a basic study that included neuroimaging, extra/intracranial vascular evaluation, 24-hour monitoring, and echocardiogram
  • Patients with acute cortical infarction with the presence of intracranial occlusion (preferably)
  • Modified Rankin Scale (mRS) lower to 4

Exclusion Criteria6

  • Diagnosis of lacunar infarction or transient ischemic attack (TIA)
  • Diagnosis of stroke of known source: atherothrombotic due to moderate or severe symptomatic extra/intracranial stenosis, major cardioembolic cause (atrial fibrillation, anterior or apical ventricular akinesis, causal PFO, post-AMI, flutter or mitral stenosis), unusual cause (thrombophilia, arterial dissection symptomatic, toxic)
  • Use of pacemakers
  • Circumstances that may preclude the clinical follow-up or reduce the possibilities of obtaining data to achieve the objectives of the study and/or limit contact with the investigator (for example, transfer to a social health center)
  • Unwillingness to the use of cardiac monitoring wearable devices
  • Not understanding study procedures

Interventions

DEVICEECG smartwatch

Testing ECG smartwatch to detect AF or potential signs of AF

DEVICEInsertable Cardiac Monitor (ICM)

Gold-standard cardiac monitor for comparison of testing device (ECG smartwatch)

DEVICEExternal ECG Monitoring

Regular cardiac monitor for diagnosis of AF


Locations(1)

Hospital Universitari Vall d'Hebron

Barcelona, Catalonia, Spain

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NCT05565781


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