Syncope Clinical Trials

38 recruitingLast updated: June 18, 2026

There are 38 actively recruiting syncope clinical trials across 19 countries. Studies span Not Applicable, Phase 2, Phase 3. Top locations include Calgary, Alberta, Canada, Burnaby, British Columbia, Canada, Amsterdam, Netherlands. Updated daily from ClinicalTrials.gov.


Syncope Trials at a Glance

38 actively recruiting trials for syncope are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Not Applicable with 18 trials, with the heaviest enrollment activity in Calgary, Burnaby, and Amsterdam. Lead sponsors running syncope studies include University of Calgary, Centre of Postgraduate Medical Education, and Simon Fraser University.

Browse syncope trials by phase

Treatments under study

About Syncope Clinical Trials

Looking for clinical trials for Syncope? There are currently 26 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Syncope trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Syncope clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 38 trials

Recruiting

Fainting Detection And Early Warning In Syncope Evaluation Study (ARISE)

Orthostatic HypotensionReflex Syncope
Boston Scientific Corporation40 enrolled1 locationNCT07502599
Recruiting

AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

Heart FailureCardiotoxicityMyocardial Infarction+12 more
Peerbridge Health, Inc2,000 enrolled8 locationsNCT06699056
Recruiting
Not Applicable

Assessment of Stroke Volume and Cardiac Output in Response to Varying Heart Rates

Vasovagal Syncope
University of Calgary25 enrolled1 locationNCT03446326
Recruiting
Not Applicable

Postural Sway and Counterpressure Maneuvers for Pediatric Syncope

Postural Orthostatic tachycardia SyndromeOrthostatic intoleranceSyncope, Vasovagal
Simon Fraser University30 enrolled1 locationNCT05633693
Recruiting
Not Applicable

The Effect of Water Carbonation on Orthostatic Tolerance

Orthostatic HypotensionSyncopeVasovagal Syncope
Simon Fraser University25 enrolled1 locationNCT05621460
Recruiting
Not Applicable

Paediatric Syncope in the Emergency Department

Postural Orthostatic tachycardia SyndromeOrthostatic intoleranceSyncope, Vasovagal
Dr. Victoria Claydon300 enrolled1 locationNCT05555771
Recruiting
Not Applicable

Assesment of the Clinical Benefit of Provocation on Tilt-table in SYNCope Patients, TiltSYNC-trial

Vasovagal Syncope (VVS)
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)238 enrolled1 locationNCT07459478
Recruiting

In Hospital 24 Hour Observation of Syncope Patients

Syncope
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)640 enrolled1 locationNCT06472375
Recruiting

Do QT-Prolonging Drugs Cause Major Adverse Cardiac Events in Hospitalized Adults?

Ventricular arrhythmiasMedication SafetyTorsades de Pointes+3 more
St. Joseph's Healthcare Hamilton990,000 enrolled2 locationsNCT07374263
Recruiting
Not Applicable

REmote Cardiac MOnitoring of At-risk SYNCope Patients After Emergency Department Discharge -RCT

Syncope
Ottawa Hospital Research Institute580 enrolled1 locationNCT05066347
Recruiting

Observation of Clinical Routine Care for Patients With BIOTRONIK Implantable Cardiac Monitors (ICMs)

Atrial FibrillationSyncopeBradycardia+2 more
Biotronik SE & Co. KG1,400 enrolled31 locationsNCT04075084
Recruiting
Not Applicable

Cardioneuroablation for Reflex Syncope and Exercise Capacity

Syncope, Vasovagal
Centre of Postgraduate Medical Education100 enrolled1 locationNCT06440291
Recruiting
Not Applicable

Cardioneuroablation: Fragmented Atrial Potentials, Intracardiac Echocardiography and Computed Tomography

Syncope, Vasovagal
Centre of Postgraduate Medical Education100 enrolled1 locationNCT06472102
Recruiting

Cardioneuroablation for Recurrent Vasovagal Syncope and Bradyarrhythmias: The CNA-FWRD Registry

AV Block-2Nd Degree-Type 1Sinus PauseVasovagal Syncope
Rush University Medical Center300 enrolled1 locationNCT06166277
Recruiting

Genetic Markers of Cardiovascular Disease in Epilepsy

CardiomyopathiesEpilepsySeizures+2 more
Mayo Clinic600 enrolled1 locationNCT02824822
Recruiting

AVEIR™ Leadless Pacemaker (LP) United Kingdom (UK) Registry

SyncopeBradycardiaAtrio-Ventricular Block
Royal Brompton & Harefield NHS Foundation Trust300 enrolled2 locationsNCT06854484
Recruiting

National Registry of Cardioneuroablation in Recurrent Reflex Syncope

BradycardiaSyncope, VasovagalHeart Arrest
University Hospital, Bordeaux50 enrolled14 locationsNCT06159764
Recruiting
Not Applicable

Impact of Blood Phobia on Fainting Susceptibility

Syncope, VasovagalBlood, Injection, Injury Type Phobia
Simon Fraser University20 enrolled1 locationNCT06336031
Recruiting
Not Applicable

Cardioneuroablation and Ventricular Proarrhythmia

Syncope, Vasovagal
Centre of Postgraduate Medical Education50 enrolled1 locationNCT06458140
Recruiting
Not Applicable

Efficacy of a Right-sided Ablation of the Anterior Ganglionated Plexus for Neurally Mediated Syncope

SyncopeSyncope, Neurogenic
Imelda Hospital, Bonheiden110 enrolled3 locationsNCT04755101