Phase 1 CTS Clinical Trials
63 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 63 trials
Recruiting
Phase 1
An Early-stage Clinical Trial to Evaluate the Safety, Absorption, and Disposition of YR001 Ointment Following Topical Application on the Skin of Healthy Chinese Subjects
Health Adult Subjects
Hangzhou Yirui Pharmaceutical Technology Co., Ltd18 enrolled1 locationNCT07673458
Recruiting
Phase 1
A Study to Evaluate Safety, Tolerability and Pharmacokinetics of Orally Administered TIX100 in Healthy Subjects
Obesity, OverweightHealth Adult Subjects
TIXiMED, Inc.18 enrolled1 locationNCT07675590
Recruiting
Phase 1
A Phase 1, Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ISM8969
Healthy Subjects (HS)Obese Adult Participants at Risk of Cardiovascular Disease
InSilico Medicine Hong Kong Limited100 enrolled1 locationNCT07581431
Recruiting
Phase 1
A Single Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of SYH2061
Healthy Subjects
CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.40 enrolled1 locationNCT07241910
Recruiting
Phase 1
Monitoring Patients With Repetitive Head Impact With Gamma-glutamylcysteine Supplementation
Repetitive head impacts
Pravat Mandal30 enrolled1 locationNCT07050173
Recruiting
Phase 1
Bioequivalence (BE) Study Between YHP2511 and YHP2511A in Healthy Volunteers
Healthy Subjects
Yuhan Corporation60 enrolled1 locationNCT07470125
Recruiting
Phase 1
Behavioral Pharmacology of Orally Administered THC and D-limonene
THCSubjective Drug EffectsD-limonene
Johns Hopkins University65 enrolled1 locationNCT06378957
Recruiting
Phase 1
Samarium Optimized for Long-lasting Analgesia in Cancerous End-stage Bone Pain
Bone PainMetastatic Bone TumorBone Metastases in Subjects With Advanced Cancer
Telix Pharmaceuticals (Innovations) Pty Limited33 enrolled6 locationsNCT07197645
Recruiting
Phase 1
A Study to Evaluate the Safety, Tolerability, PK/PD of HEC-007 Injection in Healthy and Overweight/Obese Subjects
Healthy Subjects
Sunshine Lake Pharma Co., Ltd.126 enrolled1 locationNCT07102251
Recruiting
Phase 1
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single- and Multiple-Ascending Doses and Food Effect of BGB-45035 in Healthy Participants and in Adults With Autoimmune Dermatological Diseases
healthy adult participantsHealthy ParticipantsHealthy Volunteers+4 more
BeiGene211 enrolled13 locationsNCT06342713
Recruiting
Phase 1
A Study of JPH034 in Healthy Adult Participants
Health Adult Subjects
J-Pharma Co., Ltd.40 enrolled1 locationNCT07534657
Recruiting
Phase 1Phase 2
Immune Tolerance Induction After Liver Transplantation
Liver TransplantationEnd Stage Liver DiseaseImmune Tolerance+6 more
University of California, Los Angeles12 enrolled1 locationNCT07269041
Recruiting
Phase 1
Investigation of Psychedelic Effects in Psychoactive Substances
Psychedelic Effects in Healthy Volunteers
Johns Hopkins University50 enrolled1 locationNCT06772753
Recruiting
Phase 1
A Phase 1 Study of GTX-B001 in Healthy Subjects and Patients With Chronic Inducible Urticaria
Healthy SubjectsChronic Inducible UrticariaCold Urticaria+1 more
Granular Therapeutics Limited72 enrolled2 locationsNCT07181369
Recruiting
Phase 1
A Study to Investigate HLA-G Targeted Exosome (SOB100) in Healthy Subjects
Targeted TherapyExosomeHealthy Subjects
Shine-On Biomedical Co., Ltd.15 enrolled1 locationNCT07219940
Recruiting
Phase 1
Clinical Study to Evaluate the Effects of Oral Delta-9-tetrahydrocannabinol (Δ9-THC) With and Without Alcohol on Perception and Driving Performance in Healthy Adults
Driving performanceCannabis, Drug Effects
Food and Drug Administration (FDA)48 enrolled2 locationsNCT07176208
Recruiting
Phase 1
A Drug-Drug Interaction Study of HDM1002 and Metformin, Empagliflozin, Midazolam, Valsartan, and Warfarin
Healthy SubjectsOverweight Subject
Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.111 enrolled1 locationNCT07331389
Recruiting
Phase 1
A Real-World Study of Fecal Transplants for Cancer Therapy Side Effects
Antineoplastic AgentsGastrointestinal NeoplasmsFecal Microbiota Transplantation (FMT)+1 more
Second Affiliated Hospital, School of Medicine, Zhejiang University90 enrolled1 locationNCT07319364
Recruiting
Phase 1
A Mass Balance Study of [14C] MT1013 in Hemodialysis Subjects With Secondary Hyperparathyroidism
Hemodialysis Subjects With Secondary Hyperparathyroidism
Shaanxi Micot Pharmaceutical Technology Co., Ltd.6 enrolled1 locationNCT07284043
Recruiting
Phase 1
Phase 1 Study of Intravaginal KB15A
Healthy Subjects
ZabBio Inc.24 enrolled1 locationNCT07222020