Cushing Disease Clinical Trials

8 recruiting

Cushing Disease Trials at a Glance

8 actively recruiting trials for cushing disease are listed on ClinicalTrialsFinder across 6 cities in 2 countries. The largest study group is Phase 2 with 3 trials, with the heaviest enrollment activity in Bethesda, Los Angeles, and Commack. Lead sponsors running cushing disease studies include Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Crinetics Pharmaceuticals Inc., and Cedars-Sinai Medical Center.

Browse cushing disease trials by phase

Treatments under study

About Cushing Disease Clinical Trials

Looking for clinical trials for Cushing Disease? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cushing Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cushing Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 18 of 8 trials

Recruiting

An Investigation of Pituitary Tumors and Related Hypothalmic Disorders

ProlactinomaCushing DiseasePanhypopituitarism+1 more
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)2,000 enrolled1 locationNCT00001595
Recruiting

Long-Term Follow-Up of Survivors of Pediatric Cushing Disease

Cushing Disease
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)600 enrolled1 locationNCT03831958
Recruiting

Evaluation of Positron Emission Tomography (PET) With [18F]FET for the Detection of ACTH-Secreting Corticotroph Pituitary Neuroendocrine Tumors.

Cushing DiseaseACTH-producing Pituitary Tumour
Hospices Civils de Lyon20 enrolled1 locationNCT07463625
Recruiting

Evaluation of Intraoperative Contrast Enhanced Ultrasound for the Identification of Pituitary Adenoma in Cushing's Disease Compared to Other Pituitary Tumors

Pituitary AdenomaCushing Disease
Mayo Clinic110 enrolled1 locationNCT07335315
Recruiting

Collecting Information About Treatment Results for Patients With Cushing's Syndrome

Cushing SyndromeCushing DiseaseCushing's Disease
Memorial Sloan Kettering Cancer Center300 enrolled7 locationsNCT03364803
Recruiting
Phase 2

Multicenter Study of Seliciclib (R-roscovitine) for Cushing Disease

Cushing Disease
Cedars-Sinai Medical Center13 enrolled1 locationNCT03774446
Recruiting
Phase 2

Fimepinostat, Combination HDAC and Pi3-kinase Inhibitor Tumor-Directed Therapy for Cushing Disease

Cushing Disease
University of California, Los Angeles20 enrolled1 locationNCT05971758
Recruiting
Phase 1Phase 2

A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome

Cushing SyndromeCushing DiseaseEctopic ACTH Syndrome
Crinetics Pharmaceuticals Inc.18 enrolled1 locationNCT05804669