Cushing Syndrome Clinical Trials

16 recruiting

Cushing Syndrome Trials at a Glance

17 actively recruiting trials for cushing syndrome are listed on ClinicalTrialsFinder across 6 cities in 13 countries. The largest study group is Not Applicable with 3 trials, with the heaviest enrollment activity in Bethesda, Ann Arbor, and Basking Ridge. Lead sponsors running cushing syndrome studies include Crinetics Pharmaceuticals Inc., Hospital Italiano de Buenos Aires, and Central Hospital, Nancy, France.

Browse cushing syndrome trials by phase

Treatments under study

About Cushing Syndrome Clinical Trials

Looking for clinical trials for Cushing Syndrome? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Cushing Syndrome trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Cushing Syndrome clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 117 of 17 trials

Recruiting
Phase 2

Desmopressin Stimulation Test Performance in ACTH-Dependent Cushing Syndrome

Cushing Syndrome
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)140 enrolled1 locationNCT06635629
Recruiting
Phase 2

Pharmacokinetic (PK), Pharmacodynamic (PD) and Tolerability of Osilodrostat in Pediatric Patients With Cushing's Syndrome

Cushing Syndrome
RECORDATI GROUP12 enrolled15 locationsNCT03708900
Recruiting

Institutional Registry of Rare Diseases

ParagangliomaPheochromocytomaAmyloidosis+23 more
Hospital Italiano de Buenos Aires380 enrolled1 locationNCT06573723
Recruiting

Collecting Information About Treatment Results for Patients With Cushing's Syndrome

Cushing SyndromeCushing DiseaseCushing's Disease
Memorial Sloan Kettering Cancer Center300 enrolled7 locationsNCT03364803
Recruiting

Establishment and Clinical Application of Reference Intervals of Salivary Cortisol

Cushing SyndromeAdrenal InsufficiencyHealthy Adult
Shanghai 6th People's Hospital220 enrolled1 locationNCT07168122
Recruiting

Recovery From Cushing Syndrome and Mild Autonomous Cortisol Secretion (MACS)

Cushing Syndrome
Mayo Clinic700 enrolled1 locationNCT04543253
Recruiting

Adrenal Tumors - Pathogenesis and Therapy

PheochromocytomaAdrenocortical CarcinomaCushing Syndrome+2 more
University of Wuerzburg500 enrolled1 locationNCT00669266
Recruiting

A Block-and-Replace Therapy With Osilodrostat and Concomitant Glucocorticoid Replacement

Adrenal InsufficiencyHypercortisolismEndogenous Cushing Syndrome
University of Michigan12 enrolled1 locationNCT06430528
Recruiting

Modified Desmopressin (mDesmo) Using Cold-Kit for PET/CT

Cushing Syndrome
Post Graduate Institute of Medical Education and Research, Chandigarh100 enrolled1 locationNCT06962202
Recruiting
Phase 1Phase 2

A Study to Evaluate the Safety and PK of CRN04894 for the Treatment of Cushing's Syndrome

Cushing SyndromeCushing DiseaseEctopic ACTH Syndrome
Crinetics Pharmaceuticals Inc.18 enrolled1 locationNCT05804669
Recruiting

Cushing's Syndrome Before and After Treatment (CORRECT)

Cushing Syndrome
University of Aarhus20 enrolled1 locationNCT05521529
Recruiting
Phase 4

Effect of Metyrapone on Cardiovascular Risk Factors in Patients With Adrenal Incidentalomas and Cushing's Syndrome

Cushing SyndromeAdrenal Incidentalomas
IRCCS Azienda Ospedaliero-Universitaria di Bologna50 enrolled3 locationsNCT06801249
Recruiting
Not Applicable

NAC- NAFLD and Cushing

Cushing SyndromeFatty Liver Disease
University Hospital, Angers100 enrolled6 locationsNCT05881005
Recruiting
Not Applicable

A Single Center Randomized Controlled Study on the Promotion of Rapid Recovery

Cushing SyndromePrimary AldosteronismNonfunctional Adrenal Cortex Adenoma
Zhe Meng200 enrolled1 locationNCT06250699
Recruiting
Not Applicable

Evaluation of the Severity of Hepatic Fibrosis by Magnetic Resonance Elastography in the Diagnosis of Endogenous Hypercorticism

Metabolic SyndromeCushing Syndrome
Central Hospital, Nancy, France21 enrolled1 locationNCT05911620
Recruiting

Surgical Treatment of Adrenal Diseases- Laparoscopic vs. Robotic-assisted Adrenalectomy

PheochromocytomaAdrenocortical CarcinomaCushing Syndrome+10 more
University Hospital Olomouc100 enrolled1 locationNCT06050057
Recruiting

China Adrenal Disease Registry

PheochromocytomaCongenital Adrenal HyperplasiaCushing Syndrome+5 more
Shanghai Jiao Tong University School of Medicine2,000 enrolled1 locationNCT04890444