Phase 3 DED Clinical Trials

9 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 19 of 9 trials

Recruiting
Phase 3

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Endometrial CarcinomaEndometrial Clear Cell AdenocarcinomaEndometrial Dedifferentiated Carcinoma+5 more
National Cancer Institute (NCI)360 enrolled408 locationsNCT05256225
Recruiting
Phase 3

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Metastatic Dedifferentiated LiposarcomaStage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8+3 more
National Cancer Institute (NCI)365 enrolled250 locationsNCT06422806
Recruiting
Phase 2Phase 3

A Clinical Study Evaluating Licaminlimab for Dry Eye Disease

Dry Eye Disease (DED)
Oculis160 enrolled10 locationsNCT07548632
Recruiting
Phase 2Phase 3

Efficacy Testing of a Multi-Level Family Planning Intervention

Unintended pregnancyFamily Planning
Boston College1,464 enrolled1 locationNCT06923189
Recruiting
Phase 3

Phase III Clinical Trial Evaluating the Resection Efficacy of 5-Aminolevulinic Acid Hydrochloride (5-ALA HCl) Fluorescence-Guided Microsurgery Versus Conventional White Light Microsurgery in Patients With Malignant Glioma (WHO Grade 3/4)

Fluorescence-guided Resection5-aminolevulinic Acid
Lee's Pharmaceutical Limited144 enrolled2 locationsNCT06160492
Recruiting
Phase 3

Phase III Clinical Study of Lifitegrast Ophthalmic Solution for the Treatment of Dry Eye Disease

Dry Eye Disease (DED)
Lunan Better Pharmaceutical Co., LTD.820 enrolled1 locationNCT06879782
Active
Phase 2Phase 3

Clinical Investigation of the Extended Range of Vision (ERV) Intraocular Lenses (IOLs), Model XRA03 and Toric Series ZXT in Participants Requiring Bilateral Cataract Removal and Lens Replacement.

Bilateral Cataract removal and replacment of crystalline lens with an investigational extended range of vision IOL, in otherwise healthy eyes
Abbott Medical Optics Inc75 enrolled1 locationACTRN12613001189718
Terminated
Phase 3

dexamethasone and tramadol as additives to local anesthetics in ultrasound guided supraclavicular brachial plexus (SCBP) block and duration of analgesia.

analgesia after ultrasound guided nerve block
Tunisian Military Hospital60 enrolled1 locationACTRN12612000921886
Recruiting
Phase 3

A large-scale trial testing the intensity of CYTOreductive therapy to prevent cardiovascular events In patients with Polycythemia Vera (PV)

To assess the benefit/risk profile of cytoreductive therapy with phlebotomy and/or hydroxyurea (HU) aimed at maintaining hematocrit (HCT) < 45% Vs. maintaining HCT in the range of 45-50% in patients with PV treated at the best of recommended therapies (e.g., low dose of aspirin when indicated and adequated control of standard cardiovascular risk factors)
Consorzio Mario Negri Sud1,000 enrolled1 locationACTRN12609000046202