DED Clinical Trials

103 recruitingLast updated: May 13, 2026

There are 103 actively recruiting ded clinical trials across 42 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 4, Phase 1, Early Phase 1. Top locations include Houston, Texas, United States, Cairo, Egypt, Durham, North Carolina, United States. Updated daily from ClinicalTrials.gov.


DED Trials at a Glance

103 actively recruiting trials for ded are listed on ClinicalTrialsFinder across 6 cities in 42 countries. The largest study group is Not Applicable with 52 trials, with the heaviest enrollment activity in Houston, Cairo, and Durham. Lead sponsors running ded studies include National Cancer Institute (NCI), Cairo University, and Al-Azhar University.

Treatments under study

About DED Clinical Trials

Looking for clinical trials for DED? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new DED trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about DED clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 103 trials

Recruiting
Phase 3

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Endometrial CarcinomaEndometrial Clear Cell AdenocarcinomaEndometrial Dedifferentiated Carcinoma+5 more
National Cancer Institute (NCI)360 enrolled408 locationsNCT05256225
Recruiting
Phase 3

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Metastatic Dedifferentiated LiposarcomaStage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8+3 more
National Cancer Institute (NCI)365 enrolled250 locationsNCT06422806
Recruiting
Not Applicable

Evaluation of Changing the Scripts Intervention in Nigeria

Unintended Pregnancy Prevention
University of California, San Diego4,000 enrolled3 locationsNCT07527364
Recruiting
Not Applicable

Upper Punctal Plug Occlusion in Previous Lower Punctal Occlusion.

DEDAqueous-deficient Dry Eye Disease
Universidad Autonoma de Nuevo Leon36 enrolled1 locationNCT07571330
Recruiting
Not Applicable

Evaluation of Zygomatic Implant Placement Accuracy Using Fully Metallic vs Resin-based Static Surgical Guides in Severely Atrophic Maxilla

Dental ImplantZygomatic ImplantsAtrophic Edentulous Maxilla+2 more
Future University in Egypt4 enrolled1 locationNCT07551024
Recruiting
Phase 2Phase 3

A Clinical Study Evaluating Licaminlimab for Dry Eye Disease

Dry Eye Disease (DED)
Oculis160 enrolled10 locationsNCT07548632
Recruiting
Phase 4

The Effects of 3% Trehalose Ophthalmic Solution on Corneal Epithelial Barrier Function

Dry Eye Disease (DED)
Southern California College of Optometry at Marshall B. Ketchum University30 enrolled1 locationNCT06655441
Recruiting
Not Applicable

THE EFFECT OF GUİDED IMAGERY ON PREMENSTRUAL SYNDROME

NursingPremenstrual SyndromeGuided Imagery
Baskent University48 enrolled1 locationNCT07202650
Recruiting

Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in Endometrial Cancers

Malignant Uterine NeoplasmEndometrial Clear Cell AdenocarcinomaEndometrial Dedifferentiated Carcinoma+3 more
M.D. Anderson Cancer Center1,000 enrolled1 locationNCT05049538
Recruiting

A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score

extubation failureRespiratory FailureWeaning Invasive Mechanical Ventilation+5 more
Medipol University470 enrolled7 locationsNCT07098611
Recruiting
Not Applicable

The Effect of 0.1% Topical Ciclosporin A for 12-weeks on the Eye Surface Immune Cells in Dry Eyes

Dry Eye Disease (DED)
The University of New South Wales60 enrolled1 locationNCT06898853
Recruiting
Phase 2

Visugromab, Nivolumab and Lenvatinib Compared to Double Placebo and Lenvatinib in Unresectable or Metastatic Hepatocellular Carcinoma Post Anti-PD-(L)1 Failure

Unresectable or Metastatic Hepatocellular CarcinomaChild-Pugh A Hepatocellular CarcinomaFailure of First-Line Treatment That Included an Approved Anti PD-(L)1 Compound
CatalYm GmbH104 enrolled2 locationsNCT07219459
Recruiting
Not Applicable

Routine Probe Compression After Transrectal Prostate Biopsy(RPCAB) to Reduce Bleeding and Infectious Complications : A Randomized Controlled Trial

Prostate BiopsyTRANSRECTAL ULTRASOUND-GUIDED PROSTATE BIOPSYPost Biopsy Bleeding
Veterans Health Service Medical Center, Seoul, Korea324 enrolled1 locationNCT07550985
Recruiting
Phase 2

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Recurrent Endometrial CarcinomaEndometrial AdenocarcinomaEndometrial Clear Cell Adenocarcinoma+6 more
National Cancer Institute (NCI)81 enrolled137 locationsNCT05112601
Recruiting
Phase 1Phase 2

STC-15 as a Part of Combination Therapy With Toripalimab in Selected Advanced Cancers and as Monotherapy in Participants With Selected Sarcomas

SarcomaSolid TumorLeiomyosarcoma+1 more
STORM Therapeutics LTD107 enrolled6 locationsNCT06975293
Recruiting
Not Applicable

Endoscopic Ultrasound-Guided Radiofrequency Ablation for Pancreatic Cystic Neoplasms and Pancreatic Neuroendocrine Tumors

Endoscopic Ultrasound-Guided Radiofrequency AblationPancreatic Neuroendocrine Tumors (pNET)Pancreatic Cystic Neoplasms
Institute for Clinical and Experimental Medicine50 enrolled1 locationNCT07536087
Recruiting
Phase 1

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

Metastatic SarcomaMetastatic LeiomyosarcomaUnresectable Leiomyosarcoma+9 more
National Cancer Institute (NCI)30 enrolled16 locationsNCT05711615
Recruiting
Phase 1Phase 2

Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma

Metastatic Soft Tissue SarcomaMetastatic LeiomyosarcomaAdvanced Soft Tissue Sarcoma+5 more
National Cancer Institute (NCI)74 enrolled1 locationNCT06498648
Recruiting
Not Applicable

Assessment Of Guided Bone Regeneration Using Xenograft Mixed With Allogenic Bone Graft Versus Xenograft Mixed With Autogenous Graft For Augmentation Of Maxillary Alveolar Ridges

Guided Bone Regeneration
Cairo University32 enrolled1 locationNCT07367464
Recruiting

Digital Planning and Clinical Assessment of the Treated Atrophic Posterior Maxilla With a Sinus Lift Procedure: a Cross-sectional Study.

Peri-implant healthAlveolar Bone AtrophyProsthetic Complication+5 more
Saint-Joseph University100 enrolled1 locationNCT07526337