Phase 3 Dependence Clinical Trials

14 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 114 of 14 trials

Recruiting
Phase 3

Early Withdrawal Exposure and Negative Affect Withdrawal (NAW) Regulation Training for Smoking Cessation

Tobacco Dependence
University of Alabama at Birmingham400 enrolled1 locationNCT03912194
Recruiting
Phase 2Phase 3

Baclofen for Improving Benzodiazepine Titration in Benzodiazepine Dependence

Benzodiazepine Dependence
Hospices Civils de Lyon93 enrolled2 locationsNCT05935553
Recruiting
Phase 3

Optimizing Tobacco Use Treatment for PLWHA

Nicotine DependenceHIV/AIDS
University of Pennsylvania340 enrolled2 locationsNCT04176172
Recruiting
Phase 3

Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity.

Nicotine Dependence
Jasper A. Smits360 enrolled1 locationNCT06053567
Terminated
Phase 3

Cessation and Relapse Prevention (CARP) Trial: Nicotine vaporisers compared to standard nicotine replacement therapy for smoking cessation among people with co-morbidities.

Tobacco smoking dependence
The University of Queensland810 enrolled1 locationACTRN12618000408280
Active
Phase 3

A non-inferiority trial of cytisine versus varenicline for smoking cessation

Tobacco use and dependence
University of New South Wales1,450 enrolled1 locationACTRN12616001654448
Terminated
Phase 3

Varenicline alone or with nicotine e-cigarettes for smoking cessation in people with mental illness and drug and/or alcohol dependence.

Drug and alcohol dependenceSmoking
The University of Auckland338 enrolled1 locationACTRN12616001355460
Recruiting
Phase 3

Creatine for Depressed Male and Female Methamphetamine Users

DepressionAnxietyMethamphetamine Dependence
Montana State University29 enrolled1 locationNCT02568878
Completed
Phase 3Phase 4

Optimising Management of acute pain in Opioid Substitution Therapy patients: A pilot laboratory randomised study

Acute pain in opioid dependence
Sydney Local Health District - Royal Prince Alfred Hospital36 enrolled1 locationACTRN12612000288820
Completed
Phase 3

Intranasal oxytocin for the treatment of alcohol dependence

Alcohol Dependence
University of Sydney35 enrolled1 locationACTRN12610001061022
Recruiting
Phase 3

Intranasal oxytocin for the treatment of cannabis and alcohol dependence

Cannabis and alcohol dependence
University of Sydney80 enrolled1 locationACTRN12610000742077
Completed
Phase 3

A randomised trial of effective and cost effectiveness of supervised versus unsupervised administration of buprenorphine-naloxone for heroin dependence

Heroin dependence
Langton Centre146 enrolledACTRN12607000285459
Not Yet Recruiting
Phase 3

Baclofen for Alcohol Dependence

Alcohol Dependence
Sydney South West Area Health Service42 enrolled1 locationACTRN12606000100594
Active
Phase 3

Assessment of Services Promoting Independence and Recovery in Elders

Frailty and Independence in Older People
Ministry of Health, New Zealand Government1,100 enrolled1 locationACTRN12605000140651