Phase 1 Depression - Major Depressive Disorder Clinical Trials

7 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 1–7 of 7 trials

Recruiting

Phase 1Phase 2

Personalized Ultrasonic Brain Stimulation for Depression (R61)

Depression - Major Depressive DisorderMajor Depressive EpisodeTreatment-Resistant Major Depressive Disorder

Brian Mickey30 enrolled1 locationNCT06902298

Recruiting

Phase 1Phase 2

Modulating Spinal Interoceptive Pathways to Evaluate Their Role and Therapeutic Potential in MDD Symptomatic Domains

Depression - Major Depressive Disorder

University of Cincinnati67 enrolled1 locationNCT06795451

Recruiting

Phase 1Phase 2

Psilocybin to Treat Depression in Spinal Cord Injury

Depression - Major Depressive DisorderSpinal Cord InjuryVeteran

James J. Peters Veterans Affairs Medical Center30 enrolled1 locationNCT07251491

Recruiting

Phase 1

Elucidating the Relevance of the Psychedelic Experience to Psilocybin's Anti-Anhedonic Effects

Depression - Major Depressive DisorderAnhedonia

Medical University of Vienna85 enrolled1 locationNCT07490353

Recruiting

Phase 1

Open-Label Psilocybin Study in Transdiagnostic Population

AnxietyDepression - Major Depressive DisorderPTSD+5 more

Yale University50 enrolled1 locationNCT06442423

Recruiting

Phase 1

Use of a Generative AI (Gen-AI) Chatbot for Anxiety and Depression Among Persons With Cannabis Use

Depression, AnxietyAnxietyDepression - Major Depressive Disorder+1 more

Trustees of Dartmouth College15 enrolled1 locationNCT06920238

Recruiting

Phase 1Phase 2

Effects of Low-intensity Transcranial Magnetic Stimulation on Major Depressive Disorder, and on 5-hydroxyindoleacetic Acid and Brain-derived Neurotrophic Factor Levels

Depression - Major Depressive DisorderTranscranial Magnetic StimulationPlacebo

Universidad de Guanajuato40 enrolled1 locationNCT06667180