Phase 1 Diabetic Macular Edema Clinical Trials
11 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–11 of 11 trials
Recruiting
Phase 1
A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of RO7823653 in Participants With Diabetic Macular Edema (DME)
Diabetic Macular Edema
Genentech, Inc.93 enrolled8 locationsNCT07425522
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7446603 Administered Alone or in Combination With Aflibercept or Faricimab in Participants With Diabetic Macular Edema
Diabetic Macular Edema
Genentech, Inc.546 enrolled78 locationsNCT06850922
Recruiting
Phase 1Phase 2
Kamuvudine-9 (K9) in Diabetic Macular Edema
Diabetic Macular Edema
Dr. Bryan Strelow10 enrolled1 locationNCT07458061
Recruiting
Phase 1
A Study of Avoralstat In Participants With Diabetic Macular Edema
Diabetic Macular Edema (DME)
BioCryst Pharmaceuticals9 enrolled8 locationsNCT07228559
Recruiting
Phase 1
MS-553 in Diabetic Retinopathy Patients With Central Involved Macular Edema
Diabetic RetinopathyDiabetic Macular EdemaMacular Edema+2 more
Shenzhen MingSight Relin Pharmaceuticals Co., Ltd.45 enrolled3 locationsNCT04187443
Recruiting
Phase 1
Evaluation of K9 in Subjects With Diabetic Macular Edema (DME)
Diabetic Macular Edema
Michelle Abou-Jaoude5 enrolled1 locationNCT06781255
Recruiting
Phase 1Phase 2
EC-104 Intravitreal Implant for the Treatment of Diabetic Macular Edema
Diabetic Macular Edema
Eclipse Life Sciences, Inc.75 enrolled1 locationNCT06536491
Recruiting
Phase 1
A Study Intravitreal THN391 in Diabetic Macular Oedema Secondary to Non-Proliferative Diabetic Retinopathy.
Diabetic RetinopathyDiabetic Macular Edema
Therini Bio Pty Ltd21 enrolled2 locationsNCT06701721
Recruiting
Phase 1Phase 2
Gene Therapy for DME
Diabetic Macular Edema
Frontera Therapeutics78 enrolled1 locationNCT06492876
Recruiting
Phase 1
A Clinical Study Evaluating the Safety, Tolerability and Initial Efficacy of SKG0106 Intravitreal Injection in Diabetic Macular Edema (DME) Patients
Diabetic Macular Edema
Wang Min18 enrolled2 locationsNCT06237777
Recruiting
Phase 1
Gene Therapy for Diabetic Macular Edema
Diabetic Macular Edema
Frontera Therapeutics18 enrolled1 locationNCT05916391