Phase 1 Diarrhea Clinical Trials
6 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–6 of 6 trials
Recruiting
Phase 1
KAN-004 for Immune-Related Diarrhea or Colitis
ColitisDiarrhea Caused by Antitumor Drugs
Centre hospitalier de l'Université de Montréal (CHUM)21 enrolled1 locationNCT07196410
Recruiting
Phase 1
Fecal Microbiota Transplantation in Treating Immune-Checkpoint Inhibitor Induced-Diarrhea or Colitis in Genitourinary Cancer Patients
Breast CancerOvarian CancerCervical Cancer+6 more
M.D. Anderson Cancer Center40 enrolled1 locationNCT04038619
Recruiting
Phase 1
A Study of SER-155 to Treat Diarrhea in People on Immunotherapy
DiarrheaEnterocolitis
Memorial Sloan Kettering Cancer Center15 enrolled7 locationsNCT06801067
Recruiting
Phase 1
First in Human Dose Escalation Study Evaluating the Safety and Immunogenicity of IVT's Shigella-04 Vaccine in Healthy Young Adults
DiarrheaShigella
Inventprise Inc.60 enrolled1 locationNCT07205926
Recruiting
Phase 1
Efficacy of Repeated Transcranial Magnetic Stimulation Combined With a Live Probiotic Tablet (Combined Bifidobacterium, Lactobacillus, Enterococcus and Bacillus Cereus Tablets, Live) in Diarrhea-Predominant Irritable Bowel Syndrome (IBS-D)
Intestinal FloraIrritable Bowel SyndromeProbiotic+3 more
The First Affiliated Hospital of Soochow University400 enrolled1 locationNCT06960369
Completed
Phase 1
A three-part, double-blind, placebo-controlled, Phase I/Ib study of the safety, tolerability and pharmacokinetics of single and multiple ascending doses of IMU-856 in healthy volunteers and patients with Celiac disease
Diarrhea-predominant irritable bowel syndrome
Immunic Australia Pty Ltd120 enrolled8 locationsACTRN12620000901909