Phase 2 DIGEST Clinical Trials
19 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–19 of 19 trials
Recruiting
Phase 2
Comparing Retreatment of 177Lu-DOTATATE PRRT Versus the Usual Treatment in Patients With Metastatic Unresectable Gastroenteropancreatic Neuroendocrine Tumors, NET RETREAT Trial
Unresectable Digestive System Neuroendocrine Tumor G1Unresectable Digestive System Neuroendocrine Tumor G2Metastatic Digestive System Neuroendocrine Tumor G1+1 more
National Cancer Institute (NCI)100 enrolled36 locationsNCT05773274
Recruiting
Phase 2
Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia
Diabetes MellitusIndigestion
Mayo Clinic150 enrolled1 locationNCT03865290
Recruiting
Phase 2
Dose Individualization of Chemotherapy in Patients With Gastrointestinal Cancers Lacking a Specific Liver Enzyme
Colorectal, CancerDigestive Cancer
UNICANCER400 enrolled41 locationsNCT06475352
Recruiting
Phase 1Phase 2
A Study of BL-M07D1 in Patients With a Variety of Solid Tumors Including Locally Advanced or Metastatic HER2-positive/Low-expressing Urinary and Gastrointestinal Tumors
Her2-positive/Low-expression Urinary and Digestive Tract Tumors
Sichuan Baili Pharmaceutical Co., Ltd.42 enrolled1 locationNCT06031584
Recruiting
Phase 2
Temozolomide and Survivin Long Peptide Vaccine (SurVaxM) for the Treatment of Patients With Progressing Metastatic Neuroendocrine Carcinomas
Malignant Solid NeoplasmLung Neuroendocrine NeoplasmDigestive System Neuroendocrine Neoplasm+1 more
Roswell Park Cancer Institute60 enrolled1 locationNCT06202066
Recruiting
Phase 2
Fucoidan for Preventing Chemotherapy-Related Fatigue in Patients With Gastrointestinal or Gynecological Cancer
Malignant Female Reproductive System NeoplasmMalignant Digestive System Neoplasm
Mayo Clinic34 enrolled1 locationNCT06855524
Recruiting
Phase 2
Refractory Advanced diGestive Neuroendocrine Carcinomas Treated With tARlatamab
Advanced Neuroendocrine Carcinomas of The Digestive SystemAdvanced Neuroendocrine Carcinomas Unknown Primary Origin
Grupo Espanol de Tumores Neuroendocrinos87 enrolled19 locationsNCT07061080
Recruiting
Phase 2
A Study of AAV2-hAQP1 Gene Therapy in Participants With Radiation-Induced Late Xerostomia
Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands
MeiraGTx, LLC276 enrolled33 locationsNCT05926765
Recruiting
Phase 2
Alii Supplement Study
Energymood swingsDigestive Health+3 more
Texas Christian University68 enrolled1 locationNCT07271316
Recruiting
Phase 2
2 Versus 6 Hour Oxaliplatin Infusions in Patients With Gastrointestinal Cancers
Malignant Digestive System Neoplasm
Emory University60 enrolled3 locationsNCT03800693
Recruiting
Phase 2
A LM-302 Combination With Other Anti-Tumor Therapies Phase ll Study
Malignant Neoplasms of Digestive Organs
LaNova Medicines Zhejiang Co., Ltd.276 enrolled1 locationNCT05934331
Recruiting
Phase 2
Efficacy of Neoadjuvant Chemotherapy in Terms of DFS in Patients With Localized Digestive Neuroendocrine Carcinomas
Digestive CancerNeuroendocrine Carcinoma
GERCOR - Multidisciplinary Oncology Cooperative Group78 enrolled14 locationsNCT04268121
Recruiting
Phase 2
68Ga-PSMA PET Imaging of Upper Metastatic Gastric Cancers to Determine Eligibility to Endoradiotherapy
Upper Digestive Tract Cancer
Centre de recherche du Centre hospitalier universitaire de Sherbrooke20 enrolled1 locationNCT05214820
Recruiting
Phase 1Phase 2
To Evaluate KC1036 in the Patients with Advanced Digestive System Tumors
Digestive System Tumors
Beijing Konruns Pharmaceutical Co., Ltd.133 enrolled13 locationsNCT05260385
Recruiting
Phase 2
XELOX Combined With Anlotinib and Penpulimab vs XELOX as Adjuvant Therapy in ctDNA Positive Gastric and Esophagogastric Junction Adenocarcinoma
Gastric CancerGastroesophageal-junction CancerCarcinoma+4 more
The First Affiliated Hospital with Nanjing Medical University80 enrolled1 locationNCT05494060
Recruiting
Phase 2
KN046 Plus Regorafenib or Apatinib in MSI-H Digestive System Cancers Resistant to PD-1/PD-L1 Blockade
Digestive System Cancers
Peking University Cancer Hospital & Institute39 enrolled1 locationNCT06099821
Recruiting
Phase 2
Camrelizumab Combined With Chemoradiotherapy in Advanced Esophageal Cancer.
Esophageal NeoplasmsDigestive System NeoplasmsEsophageal Diseases
Fujian Cancer Hospital75 enrolled1 locationNCT05624099
Recruiting
Phase 2
Anlotinib Hydrochloride Capsules Combined With TQB2450 Injection in Esophageal Squamous Cell Carcinoma Patients
Esophageal Squamous Cell CarcinomaEsophageal NeoplasmsNeoplasms by Site+8 more
Jiangxi Provincial Cancer Hospital30 enrolled1 locationNCT05252078
Completed
Phase 2
A practice based trial of a combination of nutritional interventions: probiotics, glutamine and fish oils in patients experiencing psychological distress.
Mild digestive discomfort
Southern Cross University10 enrolled1 locationACTRN12620000928910