Phase 4 Disease Clinical Trials
378 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 378 trials
Recruiting
Phase 4
A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation
Chronic Obstructive Pulmonary DiseaseHyperinflation
AstraZeneca56 enrolled7 locationsNCT07073950
Recruiting
Phase 4
A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting
Crohn's DiseaseUlcerative Colitis
Takeda400 enrolled101 locationsNCT06581328
Recruiting
Phase 4
Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels
Chronic Obstructive Pulmonary Disease
Maria Joyera Rodríguez135 enrolled6 locationsNCT06334575
Recruiting
Phase 4
A Study of Zunveyl on Safety, Tolerability, Neuropsychiatric Symptoms, and Caregiver Distress in Alzheimer's Disease (RESOLVE)
Alzheimer Disease
Alpha Cognition, Inc150 enrolled5 locationsNCT07633470
Recruiting
Phase 4
Characterization of the Serotonin 2A Receptor Selective PET Tracer [18F]MH.MZ in Patients With Neurodegenerative Diseases
Parkinson DiseaseNeurodegenerative DiseasesParkinson Disease Psychosis
Vanderbilt University Medical Center75 enrolled1 locationNCT05357612
Recruiting
Phase 4
Open-label Single-arm Study to Assess the Efficacy of Mirikizumab in Patients With Inflammatory Strictures Due to CD
Crohn Disease
Alimentiv Inc.60 enrolled5 locationsNCT06997965
Recruiting
Phase 4
Vascular Trial Associated Registry Pilot
Peripheral Arterial Disease
Corewell Health West350 enrolled2 locationsNCT07076082
Recruiting
Phase 4
This a Clinical Trial to Evaluate the Efficacy of I-PRF, Povidone-Iodine and Laser as Adjuncts to Non-surgical Periodontal Treatment in Smokers and Non-Smokers Periodontitis Patients
PeriodontitisPeriodontal DiseaseSmokers+1 more
Military Hospital of Tunis50 enrolled1 locationNCT07707063
Recruiting
Phase 4
Induction of Cross-protective Antibodies for Serogroup 33 by Pneumococcal Conjugate Vaccines
VaccinePneumococcal disease
University of Alabama at Birmingham70 enrolled1 locationNCT07135453
Recruiting
Phase 4
Vitamin D2 vs Vitamin D2 Plus Calcitriol in Cholestatic Children With Vitamin D Deficiency
Cholestatic Liver DiseaseChildrenVitamin D Deficiency+1 more
Chulalongkorn University54 enrolled1 locationNCT07670611
Recruiting
Phase 4
A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease
Crohn's Disease
Takeda100 enrolled53 locationsNCT06045754
Recruiting
Phase 4
GLUCOSE-MGH: Genetic Links Understood Through Challenge With Oral Semaglutide Exposure at MGH
Genetic PredispositionType 2 DiabetesMetabolic Diseases
Massachusetts General Hospital125 enrolled1 locationNCT06003153
Recruiting
Phase 4
Single Dose Intravenous Antibiotics for Complicated Urinary Tract Infections in Children
Complicated urinary tract infectionInfectionPediatric Infectious Disease
Murdoch Childrens Research Institute452 enrolled7 locationsNCT04876131
Recruiting
Phase 4
Stopping PPI Therapy in Inactive IBD
Crohn's DiseaseUlcerative Colitis (UC)
University of Nottingham80 enrolled1 locationNCT07691138
Recruiting
Phase 4
Long-term Anticoagulation With Oral Factor Xa Inhibitor Versus Vitamin K Antagonist After Mechanical Aortic Valve Replacement
ThromboembolismAORTIC VALVE DISEASES
Joon Bum Kim1,300 enrolled16 locationsNCT04258488
Recruiting
Phase 4
A Study to Evaluate the Efficacy of Guselkumab in Chinese Participants With Crohn's Disease (CD)
Crohn Disease
Xian-Janssen Pharmaceutical Ltd.78 enrolled5 locationsNCT07310095
Recruiting
Phase 4
Rivaroxaban for Children Aged Over 2 Years With Giant Coronary Artery Aneurysms After Kawasaki Disease
Kawasaki DiseaseCoronary Artery Aneurysm
Children's Hospital of Fudan University100 enrolled1 locationNCT05643651
Recruiting
Phase 4
Evaluation System for Lecanemab Efficacy Using Gold Electrode ECL to Monitor Alzheimer's Biomarkers
Alzheimer Disease
The Fourth Affiliated Hospital of Zhejiang University School of Medicine100 enrolled1 locationNCT07688460
Recruiting
Phase 4
ASpirin Use and stAtin Strategy for Primary Prevention in Severe Coronary Calcium Score on Computed Tomography
Cardiovascular Diseases
Jung-min Ahn5,000 enrolled32 locationsNCT06676280
Recruiting
Phase 4
Optimal Care With Guselkumab in Crohn's Disease / OPTIM Study A Prospective Open Label Interventional, Multicenter Study
Crohn Disease (CD)Intensification
Groupe d'Etude Therapeutique des Affections Inflammatoires Digestives210 enrolled1 locationNCT07616687