Phase 4 Disease Clinical Trials
357 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 357 trials
Recruiting
Phase 4
A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation
Chronic Obstructive Pulmonary DiseaseHyperinflation
AstraZeneca56 enrolled7 locationsNCT07073950
Recruiting
Phase 4
Comparison of Dual Antiplatelet Therapy De-escalation by Dose Reduction Versus Switching in Patients Undergoing PCI: The Switching Antiplatelet-8 (SWAP-8) Study
Coronary Artery Disease
University of Florida78 enrolled1 locationNCT06821191
Recruiting
Phase 4
A Study to Evaluate the Efficacy of Guselkumab in Chinese Participants With Crohn's Disease (CD)
Crohn Disease
Xian-Janssen Pharmaceutical Ltd.78 enrolled5 locationsNCT07310095
Recruiting
Phase 4
The Treatment of Liver Injury After Liver Resection With Polyene Phosphatidylcholine
Hepatocellular Carcinoma (HCC)Liver Diseases
Anhui Provincial Hospital96 enrolled1 locationNCT07150624
Recruiting
Phase 4
Polygenic Risk-based Detection of Subclinical Coronary Atherosclerosis and Intervention With Statin and Colchicine
Coronary Artery Disease
Massachusetts General Hospital200 enrolled1 locationNCT05850091
Recruiting
Phase 4
Induction of Cross-protective Antibodies for Serogroup 33 by Pneumococcal Conjugate Vaccines
VaccinePneumococcal disease
University of Alabama at Birmingham70 enrolled1 locationNCT07135453
Recruiting
Phase 4
Aβ Dynamics in LLMD
Alzheimer DiseaseMajor Depressive Disorder
NYU Langone Health60 enrolled2 locationsNCT05004987
Recruiting
Phase 4
Letermovir Prophylaxis Duration Guided by CMV-Specific T-cell Monitoring After Allo-HSCT.
Graft vs Host DiseaseHematopoietic Stem Cell TransplantationCytomegalovirus Infections+1 more
WeiShi120 enrolled1 locationNCT07569653
Recruiting
Phase 4
The Bridging Antiplatelet Therapy With Cangrelor 2 Study
Coronary Arterial Disease (CAD)
University of Florida50 enrolled1 locationNCT07225842
Recruiting
Phase 4
The Effects of 3% Trehalose Ophthalmic Solution on Corneal Epithelial Barrier Function
Dry Eye Disease (DED)
Southern California College of Optometry at Marshall B. Ketchum University30 enrolled1 locationNCT06655441
Recruiting
Phase 4
Dapagliflozin on Renal Morphology and Renal Perfusion in Patients One Year After Kidney Transplantation
Chronic Kidney Diseases
University of Erlangen-Nürnberg Medical School48 enrolled1 locationNCT06560801
Recruiting
Phase 4
Comparison of Vedolizumab Treatment to Adalimumab Dose Intensification in Crohn's Disease Patients With Loss of Response or Biomarker Activity to Adalimumab on First Line With Therapeutic Drug Concentration.
Crohn's Disease
Centre Hospitalier Universitaire de Saint Etienne220 enrolled12 locationsNCT06180382
Recruiting
Phase 4
Antibiotics as Adjuncts to Periodontal Therapy:Pharmacokinetic Considerations and Dosing Strategies
AntibioticsPeriodontal DiseasesPharmacokinetics
University of Geneva, Switzerland45 enrolled1 locationNCT04669717
Recruiting
Phase 4
Recombinant Herpes Zoster Vaccine for Prevention of Cardiovascular Events and Dementia
DementiaCardiovascular Disease
Tor Biering-Sørensen162,000 enrolled2 locationsNCT07485283
Recruiting
Phase 4
Study to Evaluate the Impact of a Targeted Lipid Optimization Program on LDL-C Control in At-risk Adult Patients With Dyslipidemia
Atherosclerotic Cardiovascular Disease
Novartis Pharmaceuticals326 enrolled1 locationNCT07034690
Recruiting
Phase 4
Prevention of Postoperative Endoscopic Recurrence With Endoscopy-driven Versus Systematic Biological Therapy
Crohn Disease
Universitaire Ziekenhuizen KU Leuven292 enrolled28 locationsNCT05169593
Recruiting
Phase 4
Interleukin-23 Monoclonal Antibody for Inflammatory Bowel Disease: Efficacy and Safety
Crohn's disease and Ulcerative Colitis
Sixth Affiliated Hospital, Sun Yat-sen University200 enrolled1 locationNCT07216014
Recruiting
Phase 4
Continuous vs Intermittent Ketorolac for Pain Control in Peds CV Surgery
Congenital Heart Disease in Children
Phoenix Children's Hospital166 enrolled1 locationNCT04040452
Recruiting
Phase 4
Daridorexant to Treat Insomnia in Patients With Mild Cognitive Impairment and Mild to Moderate Alzheimer Disease
SleepAlzheimer DiseaseInsomnia Disorder
University Hospital, Montpellier62 enrolled1 locationNCT05924425
Recruiting
Phase 4
A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.
Chronic Obstructive Pulmonary Disease
Sanofi218 enrolled58 locationsNCT07053423