Disease Clinical Trials

8,173 recruitingLast updated: July 25, 2026

There are 8,173 actively recruiting disease clinical trials across 143 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include New York, New York, United States, Boston, Massachusetts, United States, Houston, Texas, United States. Updated daily from ClinicalTrials.gov.


Disease Trials at a Glance

8,173 actively recruiting trials for disease are listed on ClinicalTrialsFinder across 6 cities in 143 countries. The largest study group is Not Applicable with 2,889 trials, with the heaviest enrollment activity in New York, Boston, and Houston. Lead sponsors running disease studies include Assistance Publique - Hôpitaux de Paris, Mayo Clinic, and Chinese University of Hong Kong.

Treatments under study

About Disease Clinical Trials

Looking for clinical trials for Disease? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 8,173 trials

Recruiting
Phase 1

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

HealthyMild Cognitive ImpairmentAlzheimer s Disease
National Institute of Mental Health (NIMH)90 enrolled1 locationNCT07169630
Recruiting
Not Applicable

Safety and Effectiveness of the Orsiro Mission 48-mm Sirolimus Eluting Coronary Stent System in Subjects With Coronary Artery Lesions

Coronary Artery Disease
Teleflex150 enrolled23 locationsNCT06779630
Recruiting
Not Applicable

Turtle-Assisted Animal Interaction on Dental Anxiety and Physiological Parameters in Children

Dental AnxietyPediatric DiseaseAnimal-Human Bonding
Igdir University50 enrolled1 locationNCT07439289
Recruiting
Phase 2

Motixafortide for MRD Sensitization in AML

Measurable Residual DiseaseAcute Myeloid Leukemia
Washington University School of Medicine10 enrolled1 locationNCT07392970
Recruiting

Real-life Registry in Patients With Coronary Artery Disease Treated With the SELUTION Sirolimus-eluting Balloon. Selution Iberia Registry

Cardiovascular Diseases
Fundación EPIC960 enrolled11 locationsNCT07256249
Recruiting
Phase 2Phase 3

ACP-204 in Adults With Alzheimer's Disease Psychosis

Alzheimer's Disease Psychosis
ACADIA Pharmaceuticals Inc.1,074 enrolled148 locationsNCT06159673
Recruiting
Phase 3

A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease

Degenerative Disc Disease
DiscGenics, Inc.162 enrolled19 locationsNCT07254806
Recruiting
Not Applicable

Effectiveness of DITM Versus IMT in COPD Patients

COPD, Chronic Obstructive Pulmonary Disease
Sir Run Run Shaw Hospital410 enrolled9 locationsNCT06958666
Recruiting

Longitudinal Studies of Patient With FPDMM

Rare DiseasesInherited Hematological DiseasesFPDMM
National Human Genome Research Institute (NHGRI)1,000 enrolled1 locationNCT03854318
Recruiting

Deciphering the Genetic Architecture of Autoimmune Diseases

Autoimmune Diseases
National Human Genome Research Institute (NHGRI)300 enrolled2 locationsNCT06948110
Recruiting
Not Applicable

Transdiagnostic Intervention to Reduce Internalized Health-Related Stigma

CancerObesityChronic Pain+3 more
University of Florida195 enrolled1 locationNCT05561595
Recruiting
Phase 3

Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT Imaging

allogeneic stem cell transplantationCardiovascular DiseasesAcute Lung Injury+3 more
National Heart, Lung, and Blood Institute (NHLBI)210 enrolled1 locationNCT07613099
Recruiting

Natural History of Trisomy 8-Associated Autoinflammatory Disease (TRIAD) and Related Disorders

Trisomy 8 MosaicismTrisomy 8 Associated Autoinflammatory DiseaseMucosal Ulcerations
National Institute of Allergy and Infectious Diseases (NIAID)750 enrolled1 locationNCT07683104
Recruiting
Not Applicable

Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes

DementiaDiabetesHypoglycemia+1 more
Indiana University62 enrolled1 locationNCT05643144
Recruiting
Phase 2

Autologous Stem Cell Transplant for Crohn's Disease

Crohn Disease
Aaron Etra50 enrolled1 locationNCT03219359
Recruiting
Phase 2

Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

Autoimmune DiseaseProteinuriaGlomerular Disease+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)30 enrolled2 locationsNCT00977977
Recruiting

Natural History Study of CADASIL

Arterial StiffnessCardiovascular DiseaseGermline Mutation in the NOTCH 3 Gene+2 more
National Heart, Lung, and Blood Institute (NHLBI)155 enrolled1 locationNCT05072483
Recruiting

Study on the Incidence of Malignant Neoplasms in Patients With Parkinson's Disease and Heterozygous Mutation of the GBA Gene

Idiopathic Parkinson's Disease (PD)
Azienda USL Reggio Emilia - IRCCS3,000 enrolled4 locationsNCT06814431
Recruiting
Phase 4

A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation

Chronic Obstructive Pulmonary DiseaseHyperinflation
AstraZeneca56 enrolled7 locationsNCT07073950
Recruiting

Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke

StrokeBrain DiseaseVascular Diseases+1 more
National Institute of Neurological Disorders and Stroke (NINDS)450 enrolled1 locationNCT06615973