Disease Clinical Trials

4 recruiting

Frequently Asked Questions

Common questions about Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 6,685 trials

Recruiting
Phase 1

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

HealthyMild Cognitive ImpairmentAlzheimer s Disease
National Institute of Mental Health (NIMH)90 enrolled1 locationNCT07169630
Recruiting
Phase 3

A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

Alzheimers Disease
Hoffmann-La Roche800 enrolled134 locationsNCT07169578
Recruiting
Not Applicable

Effectiveness of TeleVR App in Cognitive Decline and MCI Patients

Cognitive DysfunctionAlzheimer DiseaseParkinson Disease+2 more
IRCCS Centro Neurolesi Bonino Pulejo480 enrolled1 locationNCT06793735
Recruiting

Genetic Analysis of Uncommon Disease Presentations in Non-US Populations

Rare DiseasesUndiagnosed Diseases
National Human Genome Research Institute (NHGRI)400 enrolled1 locationNCT06595940
Recruiting

Deciphering the Genetic Architecture of Autoimmune Diseases

Autoimmune Diseases
National Human Genome Research Institute (NHGRI)300 enrolled2 locationsNCT06948110
Recruiting

Frequency of Selected Single Nucleotide Polymorphisms in Huntington Disease Gene Expansion Carriers

Huntington Disease
Hoffmann-La Roche600 enrolled45 locationsNCT06667414
Recruiting

Ultra-Low Field (ULF) Point-of-Care (POC) MRI System for Brain Morphology and Pathology

Nervous System Diseases (C10 Unique ID D009422)
National Institute of Neurological Disorders and Stroke (NINDS)200 enrolled1 locationNCT06203626
Recruiting

Registry for the Improvement of Postoperative OutcomeS in Cardiac and Thoracic surgEry

DeathPostoperative ComplicationsHeart Diseases+1 more
CMC Ambroise Paré8,000 enrolled1 locationNCT03209674
Recruiting

Study of Endocrine-Related Conditions and Physiology

Endocrine Disease
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1,000 enrolled1 locationNCT03867448
Recruiting

A Comprehensive Clinical, Microbiological and Immunological Assessment of Patients With Suspected Post Treatment Lyme Disease Syndrome and Selected Control Populations

Lyme Disease
National Institute of Allergy and Infectious Diseases (NIAID)700 enrolled1 locationNCT00001539
Recruiting
Phase 2

A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)

Early Alzheimer's Disease
Merck Sharp & Dohme LLC340 enrolled71 locationsNCT07033494
Recruiting

Non-interventional Study on Guideline Directed Medical Therapy for Patients With Heart Failure (HF) in Germany

Heart FailureHeart DiseaseCardiovascular Disease+1 more
AstraZeneca438 enrolled6 locationsNCT06675552
Recruiting
Phase 2

A Phase IIb Study to Evaluate the Effect of Dapagliflozin in Combination With Baxdrostat Compared With Baxdrostat on Albuminuria in Participants With Chronic Kidney Disease and High Blood Pressure.

Chronic Kidney Disease and Hypertension
AstraZeneca218 enrolled71 locationsNCT07222917
Recruiting

An Investigation of Pituitary Tumors and Related Hypothalmic Disorders

ProlactinomaCushing DiseasePanhypopituitarism+1 more
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)2,000 enrolled1 locationNCT00001595
Recruiting

Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke

StrokeBrain DiseaseVascular Diseases+1 more
National Institute of Neurological Disorders and Stroke (NINDS)450 enrolled1 locationNCT06615973
Recruiting
Phase 2

Baricitinib in the Treatment of Kohlmeier-Degos Disease in Patients With Neurological Involvement

Kohlmeier-Degos DiseaseMalignant Atrophic PapulosisDegos Disease+1 more
National Heart, Lung, and Blood Institute (NHLBI)12 enrolled1 locationNCT06923072
Recruiting
Not Applicable

Confirming the Effects of Acupuncture Treatments to Relieve Symptoms of Gulf War Illness

Wounds and InjuriesOccupational DiseasesGulf War Syndrome+3 more
University of Utah200 enrolled10 locationsNCT06716411
Recruiting
Phase 2

Phase 2 Study of SAT-3247 in Pediatric Ambulatory Patients

Duchenne Muscular DystrophyDMDNeuromuscular Diseases+2 more
Satellos Bioscience, Inc.51 enrolled19 locationsNCT07287189
Recruiting
Phase 2

Tirzepatide in MetALD

Alcohol Use DisorderMetabolic Alcohol-associated Liver Disease
National Institute on Alcohol Abuse and Alcoholism (NIAAA)120 enrolled1 locationNCT07046819
Recruiting
Not Applicable

Effects of Real vs. Soundless Acoustic Stimulation During Deep Sleep on Brain Activity, Memory, and Blood Biomarkers in Older Adults (60-85) With Mild Memory Impairment

Cognitive DeclineAlzheimer DiseaseMild Cognitive Impairment (MCI)+2 more
University of Bern60 enrolled1 locationNCT06669546