Disease Clinical Trials

7,595 recruitingLast updated: May 13, 2026

There are 7,595 actively recruiting disease clinical trials across 140 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include New York, New York, United States, Boston, Massachusetts, United States, Houston, Texas, United States. Updated daily from ClinicalTrials.gov.


Disease Trials at a Glance

7,595 actively recruiting trials for disease are listed on ClinicalTrialsFinder across 6 cities in 140 countries. The largest study group is Not Applicable with 2,668 trials, with the heaviest enrollment activity in New York, Boston, and Houston. Lead sponsors running disease studies include Assistance Publique - Hôpitaux de Paris, Mayo Clinic, and Chinese University of Hong Kong.

Treatments under study

About Disease Clinical Trials

Looking for clinical trials for Disease? There are currently 4 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 7,595 trials

Recruiting

Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance

Aneurysm ThoracicVascular DiseaseDissection+5 more
W.L.Gore & Associates1,500 enrolled34 locationsNCT06658730
Recruiting

A Prospecitve Multicenter, Observational Registry Study

Chronic Kidney Disease
AstraZeneca3,000 enrolled1 locationNCT07481526
Recruiting

Study for Assessing the Prevalence of Airflow Limitation in Outpatients With History of Smoking Attending Cardiology Clinics

Respiratory (Chronic Obstructive Pulmonary Disease)
AstraZeneca1,000 enrolled2 locationsNCT07315958
Recruiting
Phase 1Phase 2

A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell Disease

Sickle Cell Disease
Novartis Pharmaceuticals161 enrolled3 locationsNCT06546670
Recruiting

Deciphering the Genetic Architecture of Autoimmune Diseases

Autoimmune Diseases
National Human Genome Research Institute (NHGRI)300 enrolled2 locationsNCT06948110
Recruiting
Phase 2

Safety of Anumigilimab (CSL324) in Adults With Sickle Cell Disease (SCD)

Sickle Cell Disease
CSL Behring63 enrolled5 locationsNCT07224360
Recruiting
Phase 3

Assessing the Impact of Muvalaplin on Major Cardiovascular Events in Adults With Elevated Lipoprotein(a)

Atherosclerotic Cardiovascular Disease (ASCVD)Elevated Lp(a)
Eli Lilly and Company10,450 enrolled754 locationsNCT07157774
Recruiting
Phase 3

A Study to Investigate the Efficacy, Safety and Tolerability of Votoplam in Participants With Huntington's Disease

Huntington Disease
Novartis Pharmaceuticals770 enrolled10 locationsNCT07326709
Recruiting

Non-interventional Study on Guideline Directed Medical Therapy for Patients With Heart Failure (HF) in Germany

Heart FailureHeart DiseaseCardiovascular Disease+1 more
AstraZeneca438 enrolled6 locationsNCT06675552
Recruiting
Phase 2

Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

Alzheimer DiseaseAgitation
Celgene120 enrolled53 locationsNCT06808984
Recruiting

Prenatal Maternal Mental Health and Neurodevelopment in Congenital Heart Disease

Hypoplastic Left Heart SyndromeCongenital Heart DiseaseCyanotic congenital heart disease+1 more
Institut National de la Santé Et de la Recherche Médicale, France174 enrolled5 locationsNCT06711666
Recruiting
Phase 3

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

Crohn's DiseaseObesity or Overweight
Eli Lilly and Company290 enrolled187 locationsNCT06937099
Recruiting
Phase 3

Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)

Psychosis Associated With Alzheimer's Disease
Karuna Therapeutics, Inc., a Bristol Myers Squibb company800 enrolled421 locationsNCT05980949
Recruiting
Phase 1

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

HealthyMild Cognitive ImpairmentAlzheimer s Disease
National Institute of Mental Health (NIMH)90 enrolled1 locationNCT07169630
Recruiting

Screening for Social Determinants of Health (SDOH) and Cognitive Function in Individuals With History of Stroke

StrokeBrain DiseaseVascular Diseases+1 more
National Institute of Neurological Disorders and Stroke (NINDS)450 enrolled1 locationNCT06615973
Recruiting

Prospective Evaluation of the Carbon Footprint and Clinical Utility of IBUS Compared to Colonoscopy and Enterography in UC and CD

Ulcerative Colitis (UC)Crohns Disease
Asian Institute of Gastroenterology, India200 enrolled2 locationsNCT07431983
Recruiting
Phase 2

A Study of ONO-2020 in Patients With Agitation Associated With Alzheimer's Disease Dementia

Agitation Associated With Alzheimer's Disease Dementia
Ono Pharmaceutical Co., Ltd.90 enrolled38 locationsNCT06803823
Recruiting
Phase 2

Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

Autoimmune DiseaseProteinuriaGlomerular Disease+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)30 enrolled2 locationsNCT00977977
Recruiting

Fontan Associated Liver Disease and the Evaluation of Biomarkers for Disease Severity Assessment

Congenital Heart Disease
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)100 enrolled1 locationNCT05213598
Recruiting

Evaluation of Adults With Endocrine and Metabolic-Related Conditions

Endocrine Diseases
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)1,250 enrolled1 locationNCT02830308