Disorder of Consciousness Clinical Trials

17 recruiting

Disorder of Consciousness Trials at a Glance

17 actively recruiting trials for disorder of consciousness are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 10 trials, with the heaviest enrollment activity in Shanghai, Hessisch Oldendorf, and Guangzhou. Lead sponsors running disorder of consciousness studies include Huashan Hospital, BDH-Klinik Hessisch Oldendorf, and University of Liege.

Browse disorder of consciousness trials by phase

Treatments under study

About Disorder of Consciousness Clinical Trials

Looking for clinical trials for Disorder of Consciousness? There are currently 17 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Disorder of Consciousness trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Disorder of Consciousness clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 117 of 17 trials

Recruiting
Not Applicable

Study on the Effectiveness and Safety of Temporal Interference Stimulation in Treating Patients With Severe Consciousness Disorders

Disorder of ConsciousnessTemporal Interference Stimulation
Huashan Hospital20 enrolled2 locationsNCT06896279
Recruiting
Not Applicable

Robotic vs. Traditional Verticalization in Patients With Severe Acquired Brain Injury: a Randomized Controlled Trial

Disorder of ConsciousnessAcquired Brain Injury
Anna Estraneo118 enrolled6 locationsNCT06469983
Recruiting

Prognostic Factors to Regain Consciousness

Traumatic Brain InjuryStrokeNeurologic Disorder+1 more
BDH-Klinik Hessisch Oldendorf130 enrolled1 locationNCT04445649
Recruiting
Not Applicable

Effectiveness of Music Therapy on Level of Consciousness

Traumatic Brain InjuryNeurologic DisorderDisorder of Consciousness
BDH-Klinik Hessisch Oldendorf66 enrolled1 locationNCT04442971
Recruiting

An Ethical Approach to Detecting Covert Consciousness

Disorder of Consciousness
Massachusetts General Hospital70 enrolled1 locationNCT05010265
Recruiting

Emotional and Neutral Sounds for Neurophysiological Prognostic Assessment of Critically Ill Patients With a Disorder of Consciousness

Disorder of Consciousness
Assistance Publique - Hôpitaux de Paris114 enrolled2 locationsNCT05740735
Recruiting
Not Applicable

Music Intervention and Transcranial Electrical Stimulation for Neurological Diseases

StrokeDisorder of Consciousness
Istituti Clinici Scientifici Maugeri SpA90 enrolled1 locationNCT05706831
Recruiting

Evaluation of the MuSICCA for Measuring Awareness

Disorder of Consciousness
The Children's Trust, United Kingdom80 enrolled3 locationsNCT04050995
Recruiting
Phase 2Phase 3

Apomorphine in Severe Brain-injured Patients

Disorder of Consciousness
University of Liege48 enrolled4 locationsNCT05213169
Recruiting
Not Applicable

Efficacy and Safety of Spinal Cord Stimulation in Patients With Spinal Cord Stimulation

Disorder of ConsciousnessSpinal Cord Stimulation
Huashan Hospital50 enrolled3 locationsNCT06515132
Recruiting

Improving the Diagnostic Accuracy of Children with DoC (IDeAl DesiRE)

Disorder of ConsciousnessAcquired Brain Injury
IRCCS Eugenio Medea113 enrolled1 locationNCT06635291
Recruiting
Not Applicable

Awareness Detection and Communication in Disorders of Consciousness

StrokeDisorder of ConsciousnessMotor Neuron Disease+2 more
University of Ulster30 enrolled18 locationsNCT03827187
Recruiting
Not Applicable

Electro-acupuncture to Treat Disorder of Consciousness

ElectroacupunctureDisorder of Consciousness
The Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine50 enrolled1 locationNCT06268236
Recruiting
Not Applicable

Effects of Individualized rTMS in DOC Patients

Disorder of ConsciousnessTranscranial Magnetic Stimulation
Qiuyou Xie30 enrolled1 locationNCT05187000
Recruiting
Not Applicable

Effects of rTMS With Different Stimulation Spots in Patients With Disorders of Consciousness

Disorder of Consciousness
Zhujiang Hospital84 enrolled1 locationNCT06527573
Recruiting
Not Applicable

HD-tDCS Combined With Circadian Rhythm Reconstruction and Micro Expression Changes on Consciousness Recovery in Patients With Chronic Disturbance of Consciousness

Disorder of Consciousness
First Affiliated Hospital of Zhejiang University90 enrolled1 locationNCT05285124
Recruiting
Phase 2Phase 3

Ketamine to Treat Patients With Post-comatose Disorders of Consciousness

Disorder of Consciousness
University of Liege30 enrolled1 locationNCT05343507