Phase 2 Disorder Clinical Trials

564 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 564 trials

Recruiting
Phase 2

Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas

LymphomaEpstein-Barr Virus InfectionsLymphoproliferative Disorder+1 more
National Cancer Institute (NCI)40 enrolled1 locationNCT03258567
Recruiting
Phase 2

GLP-1R Agonist Treatment for Opioid Use Disorder

Opioid-use DisorderSubstance-Related DisordersOpioid+4 more
Milton S. Hershey Medical Center200 enrolled4 locationsNCT06548490
Recruiting
Phase 2

A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)

ObesityBody WeightOverweight+5 more
Pfizer872 enrolled65 locationsNCT07575932
Recruiting
Phase 2

A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety

DepressionAnxietyMajor Depressive Disorder
Ohio State University40 enrolled1 locationNCT06820723
Recruiting
Phase 2

Semaglutide Therapy for Alcohol Reduction (STAR)

Alcohol Use DisorderAddiction
National Institute on Drug Abuse (NIDA)80 enrolled1 locationNCT06015893
Recruiting
Phase 2

An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)

REM Sleep Behavior Disorder
Yale University108 enrolled20 locationsNCT06996652
Recruiting
Phase 2

A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder

Major Depressive Disorder
Syndeio Biosciences, Inc164 enrolled32 locationsNCT07115329
Recruiting
Phase 2

Tirzepatide in MetALD

Alcohol Use DisorderMetabolic Alcohol-associated Liver Disease
National Institute on Alcohol Abuse and Alcoholism (NIAAA)120 enrolled1 locationNCT07046819
Recruiting
Phase 2

Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety

Anxiety DisordersPsychiatric Disorders
National Institute of Mental Health (NIMH)150 enrolled1 locationNCT06595953
Recruiting
Phase 2

Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History

Mild Cognitive ImpairmentAmnestic Mild Cognitive ImpairmentAmnestic Mild Cognitive Disorder+2 more
University of Texas Southwestern Medical Center75 enrolled1 locationNCT05446584
Recruiting
Phase 2

Allogeneic Hematopoietic Cell Transplantation for Peripheral T Cell Lymphoma

Lymphoproliferative DisordersImmune System DiseasesPeripheral T-cell Lymphomas
National Cancer Institute (NCI)330 enrolled2 locationsNCT03922724
Recruiting
Phase 2

Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders

Major Depressive DisorderAnxiety Disorders
National Institute of Mental Health (NIMH)3,500 enrolled2 locationsNCT00018057
Recruiting
Phase 2

A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)

Bipolar Disorder
Eli Lilly and Company400 enrolled87 locationsNCT07286175
Recruiting
Phase 1Phase 2

Study to Assess Safety of HDP-101 in Patients With Relapsed Refractory Multiple Myeloma

Multiple MyelomaPlasma Cell Disorder
Heidelberg Pharma AG78 enrolled24 locationsNCT04879043
Recruiting
Phase 2

Outpatient Buprenorphine Induction With Psilocybin for Opioid Use Disorder

Opioid-use Disorder
Johns Hopkins University90 enrolled1 locationNCT06067737
Recruiting
Phase 2

Gabapentin for Restoring GABA/Glutamate Homeostasis in Co-occurring Bipolar and Cannabis Use Disorders

Cannabis UseBipolar DisorderSchizoaffective Disorder, Bipolar Type+5 more
Medical University of South Carolina68 enrolled1 locationNCT05064319
Recruiting
Phase 2

Evaluation of Tirzepatide as an Adjunct to Buprenorphine for the Treatment of Opioid Use Disorder

Opioid-use DisorderOpioid Use Disorder, ModerateOpioid Use Disorder, Severe
T. John Winhusen, PhD310 enrolled9 locationsNCT06651177
Recruiting
Phase 2

A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression

Major Depressive Disorder (MDD)
Draig Therapeutics Ltd118 enrolled11 locationsNCT07610473
Recruiting
Phase 1Phase 2

Prospective Clinical Study on Human Umbilical Cord Mesenchymal Stem Cell-Derived Exosomes for the Treatment of Childhood Autism

Autism Spectrum Disorder (ASD)Prospective Study
Dongfang People's Hospital60 enrolled1 locationNCT07243561
Recruiting
Phase 2

Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness

Depression, AnxietySchizophreniaPsychiatric Disorder+5 more
Brigham and Women's Hospital180 enrolled2 locationsNCT06376734