Phase 2 Disorder Clinical Trials
528 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 528 trials
Recruiting
Phase 2
Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Bipolar I Disorder
Bipolar 1 Disorder
Rapport Therapeutics Inc.250 enrolled22 locationsNCT07046494
Recruiting
Phase 2
Semaglutide Therapy for Alcohol Reduction (STAR)
Alcohol Use DisorderAddiction
National Institute on Drug Abuse (NIDA)80 enrolled1 locationNCT06015893
Recruiting
Phase 2
Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders
Major Depressive DisorderAnxiety Disorders
National Institute of Mental Health (NIMH)3,500 enrolled2 locationsNCT00018057
Recruiting
Phase 2
A Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive Disorder
Depressive Disorder, Major
Janssen Research & Development, LLC100 enrolled44 locationsNCT06785012
Recruiting
Phase 2
Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.
Bipolar I Disorder
LB Pharmaceuticals Inc.320 enrolled26 locationsNCT07494305
Recruiting
Phase 2
ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant Response
Major Depressive Disorder (MDD)Depressive Disorder, Treatment-Resistant
ACADIA Pharmaceuticals Inc.153 enrolled16 locationsNCT07284667
Recruiting
Phase 2
Correcting Circadian Rhythms to Breakthrough in Bipolar Disorder
Bipolar DisorderDelayed sleep-wake phase disorder
Leslie Swanson50 enrolled1 locationNCT06226025
Recruiting
Phase 2
Melatonin Versus Placebo for Bipolar Disorder
Bipolar Affective Disorder
Lars Vedel Kessing200 enrolled1 locationNCT07472075
Recruiting
Phase 2
Guanfacine for Alcohol Use Disorder (AUD)
Alcohol Use Disorder
Indiana University200 enrolled2 locationsNCT06629259
Recruiting
Phase 2
Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas
LymphomaEpstein-Barr Virus InfectionsLymphoproliferative Disorder+1 more
National Cancer Institute (NCI)40 enrolled1 locationNCT03258567
Recruiting
Phase 1Phase 2
Intestinal Microbiota Transplant in Alcohol-Associated Liver Disease
CirrhosisAlcohol Use DisorderLiver Disease; Alcohol-Related
Virginia Commonwealth University80 enrolled2 locationsNCT05548452
Recruiting
Phase 2
Probiotic Treatment for Depression and Associated Mood Disorders in Parkinson's Disease
DepressionParkinson DiseasePARKINSON DISEASE (Disorder)
University of British Columbia60 enrolled1 locationNCT05568498
Recruiting
Phase 2
Pathways Relating Amnestic MCI to a Mild Traumatic Brain Injury History
Mild Cognitive ImpairmentAmnestic Mild Cognitive ImpairmentAmnestic Mild Cognitive Disorder+2 more
University of Texas Southwestern Medical Center75 enrolled1 locationNCT05446584
Recruiting
Phase 2
Lemborexant for the Treatment of Residual Insomnia in Major Depressive Disorder (MDD)
Major Depressive Disorder (MDD)Insomnia Comorbid to Psychiatric Disorder
Unity Health Toronto30 enrolled1 locationNCT06843187
Recruiting
Phase 2
The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects
Depressive DisorderPost Traumatic Stress DisorderSuicidal Ideation+2 more
Yale University30 enrolled1 locationNCT05786066
Recruiting
Phase 2
Sex Differences in Neurobehavioral Response to THC
Cannabis Use Disorder
Medical University of South Carolina40 enrolled1 locationNCT07225777
Recruiting
Phase 2
Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD)
Immune DysregulationPrimary Immune Regulatory DisorderChronic Granulomatous Disease+12 more
Paul Szabolcs25 enrolled1 locationNCT07284641
Recruiting
Phase 2
Psilocybin Therapy for Psychological Distress in Palliative Patients
COPD, Chronic Obstructive Pulmonary DiseaseMajor Depressive Disorder (MDD)ALS (Amyotrophic Lateral Sclerosis)+2 more
University Medical Center Groningen108 enrolled4 locationsNCT06782724
Recruiting
Phase 2
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
Adjustment Disorder
Reunion Neuroscience Inc100 enrolled28 locationsNCT07002034
Recruiting
Phase 2
Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety
Anxiety DisordersPsychiatric Disorders
National Institute of Mental Health (NIMH)150 enrolled1 locationNCT06595953