Phase 3 Disorder Clinical Trials
208 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 208 trials
Recruiting
Phase 3
Studying Solriamfetol Modulation of TAAR-1, Dopamine, and Norepinephrine in Shift Work Disorder (SUSTAIN)
Shift-work DisorderExcessive Sleepiness
Axsome Therapeutics, Inc.520 enrolled49 locationsNCT06568367
Recruiting
Phase 3
Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol
Major Depressive Disorder With Excessive Daytime Sleepiness Symptoms
Axsome Therapeutics, Inc.508 enrolled40 locationsNCT07484217
Recruiting
Phase 3
A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)
Bipolar Disorder Type I With Mania
Bristol-Myers Squibb450 enrolled174 locationsNCT06929273
Recruiting
Phase 3
Cognitive Strategies in Early Psychosis 2
Major Depressive Disorder with Psychotic featuresCognitionPsychosis+6 more
University of Minnesota24 enrolled1 locationNCT07263022
Recruiting
Phase 3
Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder (ASD) in Pediatric Patients
Irritability Associated With Autism Spectrum Disorder
Intra-Cellular Therapies, Inc.160 enrolled40 locationsNCT06706674
Recruiting
Phase 3
Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
Major Depressive Disorder
Intra-Cellular Therapies, Inc.470 enrolled69 locationsNCT05850689
Recruiting
Phase 3
A Study to Evaluate the Maintenance Effect of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Major Depressive Disorder
Neurocrine Biosciences550 enrolled60 locationsNCT07196501
Recruiting
Phase 3
Multicenter Study of Lumateperone for the Treatment of Irritability Associated With Autism Spectrum Disorder in Pediatric Patients
Irritability Associated With Autism Spectrum Disorder
Intra-Cellular Therapies, Inc.160 enrolled35 locationsNCT06690398
Recruiting
Phase 3
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Major Depressive Disorder
Neurocrine Biosciences850 enrolled106 locationsNCT06966401
Recruiting
Phase 3
A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder
Alcohol Use Disorder
Eli Lilly and Company1,100 enrolled120 locationsNCT07219966
Recruiting
Phase 3
A Study of Brenipatide in Participants With Alcohol Use Disorder
Alcohol Use Disorder
Eli Lilly and Company1,100 enrolled117 locationsNCT07219953
Recruiting
Phase 3
Emergency Department-Initiated Medications for Alcohol Use Disorder
Alcohol Use Disorder
Yale University240 enrolled1 locationNCT05827159
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)
Bipolar Disorder Type I With Mania or Mania With Mixed Features
Bristol-Myers Squibb274 enrolled85 locationsNCT06951711
Recruiting
Phase 3
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Depressive Disorder, Major
Eli Lilly and Company1,000 enrolled180 locationsNCT07412756
Recruiting
Phase 3
The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive Disorder
Major Depressive Disorder
Sharmin Ghaznavi20 enrolled1 locationNCT06247839
Recruiting
Phase 3
Beeline: A Phase 3 Study in GRIN-related Neurodevelopmental Disorder
GRIN-related Neurodevelopmental Disorder
GRIN Therapeutics, Inc.100 enrolled34 locationsNCT07224581
Recruiting
Phase 3
Effect of Psilocybin and Structured Integrated Reframing Therapy on Gut-Brain Axis Biomarkers and Depression in Major Depressive Disorder
Post Traumatic Stress Disorder (PTSD)Major Depressive Disorder
Khyber Medical University Peshawar60 enrolled3 locationsNCT07703722
Recruiting
Phase 3
Intestinal Levodopa + Entacapone Therapy (Lecigon®) to Counteract Dopaminergic Desensitization and Neuropsychiatric Complications in Parkinson's Disease
PARKINSON DISEASE (Disorder)
University Hospital Tuebingen150 enrolled7 locationsNCT07151378
Recruiting
Phase 3
A Study To Evaluate Pharmacokinetics, Efficacy, Safety, Tolerability, And Pharmacodynamics Of Satralizumab In Pediatric Patients With Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorder (NMOSD)
Neuromyelitis Optica Spectrum DisorderNMOSD
Hoffmann-La Roche8 enrolled13 locationsNCT05199688
Recruiting
Phase 2Phase 3
Autologous Platelet Rich Plasma (PRP) Intra Ovarian Infusion in Perimenopausal Women
Infertility, FemaleMenstrual Cycle AbnormalPerimenopausal Disorder
Genesis Athens Clinic100 enrolled1 locationNCT03951194