Phase 4 Disorder Clinical Trials

161 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 161 trials

Recruiting
Phase 4

A Study of Esketamine Nasal Spray in Korean Participants With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant
Janssen Korea, Ltd., Korea47 enrolled6 locationsNCT07053345
Recruiting
Phase 4

CLOZAPINE Response in Biotype-1

SchizophreniaSchizoaffective DisorderBipolar 1 Disorder
University of Texas Southwestern Medical Center524 enrolled5 locationsNCT04580134
Recruiting
Phase 4

Efficacy and Safety of Cerebrolysin on Prolonged Disorders of Consciousness

Disorder of ConsciousnessHemorrhagic Stroke
Konkuk University Medical Center12 enrolled1 locationNCT04427241
Recruiting
Phase 4

A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

SchizophreniaMajor Depressive DisorderBipolar Disorder+2 more
Neurocrine Biosciences50 enrolled21 locationsNCT07105111
Recruiting
Phase 4

Allopregnanolone and Dynamic GABA-A Receptor Plasticity in Selective Serotonin Reuptake Inhibitor Responsive Premenstrual Dysphoric Disorder

Premenstrual Dysphoric Disorder (PMDD)
Johns Hopkins University288 enrolled2 locationsNCT06704594
Recruiting
Phase 4

Mismatch vs. Standard Intervention During Memory Reconsolidation Blockade With Propranolol: Effect on Psychophysiological Reactivity During Traumatic Imagery

Stress Disorders, Post-Traumatic
Massachusetts General Hospital80 enrolled1 locationNCT05853627
Recruiting
Phase 4

Aβ Dynamics in LLMD

Alzheimer DiseaseMajor Depressive Disorder
NYU Langone Health60 enrolled2 locationsNCT05004987
Recruiting
Phase 4

Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment.

Opioid-use Disorder
Yale University600 enrolled6 locationsNCT06323824
Recruiting
Phase 4

Symptom-Inhibited Naloxone Induction (SINI) for Buprenorphine Initiation: A Feasibility Trial

Opioid-use Disorder
Pouya Azar12 enrolled2 locationsNCT07439549
Recruiting
Phase 4

Clozapine for the Prevention of Violence in Schizophrenia: a Randomized Clinical Trial

SchizophreniaSchizoaffective Disorder
New York State Psychiatric Institute280 enrolled7 locationsNCT05208190
Recruiting
Phase 4

Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL

PreeclampsiaHypertensive Disorders of PregnancyGestational Hypertension
Ohio State University10,742 enrolled16 locationsNCT06468202
Recruiting
Phase 4

Beta-Adrenergic Modulation of Drug Cue Reactivity

Tobacco Use DisorderNicotine DependenceCigarette Smoking
University of Oklahoma80 enrolled1 locationNCT05587361
Recruiting
Phase 4

Establishing Multimodal Brain Biomarkers for Treatment Selection in Depression

Major Depressive DisorderChronic Major Depression, Recurrent
University of Texas at Austin50 enrolled1 locationNCT05892744
Recruiting
Phase 4

An Open-Label Treatment With Randomization Observation, Investigator-Initiated Study, on the Duration and Efficacy of Jornay PM (Methylphenidate Hydrochloride Extended-Release Capsules) on Adult ADHD Symptoms and Executive Function and Emotional Regulation Throughout the Day Into Early Evening

Attention Deficit Hyperactivity Disorder
NYU Langone Health30 enrolled1 locationNCT06577779
Recruiting
Phase 4

Fluid Challenge and Plasma Volume, During Surgery

Colorectal, CancerGynecologic CancerUrologic Cancer+2 more
Joachim Zdolsek60 enrolled1 locationNCT05726136
Recruiting
Phase 4

Skin Preparation for Elective Foot and Ankle Surgery

Microbial ColonizationFoot and Ankle Disorders
University of Missouri-Columbia100 enrolled1 locationNCT05401292
Recruiting
Phase 4

Biomarkers to Enhance Early Schizophrenia Treatment

Schizophenia Disorder
Northwell Health180 enrolled2 locationsNCT06969755
Recruiting
Phase 4

Daridorexant to Treat Insomnia in Patients With Mild Cognitive Impairment and Mild to Moderate Alzheimer Disease

SleepAlzheimer DiseaseInsomnia Disorder
University Hospital, Montpellier62 enrolled1 locationNCT05924425
Recruiting
Phase 4

SWIFT - SWIss Factor XIII Trial in PPH

Postpartum ComplicationCoagulation DisorderPostpartum Hemorrhage+2 more
Christian Haslinger988 enrolled9 locationsNCT06481995
Recruiting
Phase 4

Taper Or Abrupt Steroid Stop: TOASSTtrial

AutoimmuneInflammatory Disorder
University Hospital, Basel, Switzerland530 enrolled16 locationsNCT03153527