Phase 4 Disorder Clinical Trials

167 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 167 trials

Recruiting
Phase 4

Temporally-Resolved Electrophysiology of Acamprosate Treatment of Alcohol Use Disorder

Alcohol Use Disorder
National Institute on Alcohol Abuse and Alcoholism (NIAAA)48 enrolled1 locationNCT06269627
Recruiting
Phase 4

Tirzepatide's Role in Postmenopausal HR+ Breast Cancer Survivors

Breast CancerObesity (Disorder)
Weill Medical College of Cornell University30 enrolled1 locationNCT07257484
Recruiting
Phase 4

Exercise and Olanzapine-samidorphan

Schizoaffective DisorderSchizophenia DisorderBipolar Disorder I or II+1 more
New York State Psychiatric Institute30 enrolled1 locationNCT06740890
Recruiting
Phase 4

Anticholinergic Deprescription in Schizophrenia

SchizophreniaSchizoaffective Disorder
Deepak K. Sarpal, M.D.105 enrolled1 locationNCT06562608
Recruiting
Phase 4

Atomoxetine and Executive Function in PTSD

Posttraumatic Stress Disorder With Attention Defic
VA Office of Research and Development160 enrolled1 locationNCT06573970
Recruiting
Phase 4

Daridorexant to Treat Insomnia in Patients With Mild Cognitive Impairment and Mild to Moderate Alzheimer Disease

SleepAlzheimer DiseaseInsomnia Disorder
University Hospital, Montpellier62 enrolled1 locationNCT05924425
Recruiting
Phase 4

A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) Inhibitor

SchizophreniaMajor Depressive DisorderBipolar Disorder+2 more
Neurocrine Biosciences50 enrolled22 locationsNCT07105111
Recruiting
Phase 4

Optimizing Evidence-based HIV Prevention Targeting People Who Inject Drugs on PrEP

Opioid-use DisorderHIV
University of Connecticut256 enrolled1 locationNCT05669534
Recruiting
Phase 4

Computational Assessment of GABA Receptor Modulation in PTSD

Stress Disorders, Post-Traumatic
VA Office of Research and Development150 enrolled1 locationNCT06852469
Recruiting
Phase 4

Biomarkers to Enhance Early Schizophrenia Treatment

Schizophenia Disorder
Northwell Health180 enrolled5 locationsNCT06969755
Recruiting
Phase 4

E-cigarette Cessation in Adults Who Co-use Cannabis

Tobacco Use DisorderNicotine Dependence
Medical University of South Carolina105 enrolled3 locationsNCT06688539
Recruiting
Phase 4

Optimized Predictive Treatment In Medications for Unipolar Major Depression (OPTIMUM-D)

Major Depressive Disorder
Nova Scotia Health Authority400 enrolled10 locationsNCT05017311
Recruiting
Phase 4

A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for Insomnia

InsomniaChronic InsomniaInsomnia Disorder+1 more
University of Pennsylvania1,200 enrolled1 locationNCT07542756
Recruiting
Phase 4

A Study of Esketamine Nasal Spray in Korean Participants With Treatment-resistant Depression

Depressive Disorder, Treatment-Resistant
Janssen Korea, Ltd., Korea47 enrolled6 locationsNCT07053345
Recruiting
Phase 4

Treatment With Aspirin After Preeclampsia: TAP Trial

Cardiovascular DiseasesHypertensionPregnancy Complications+8 more
Malamo Countouris60 enrolled1 locationNCT06281665
Recruiting
Phase 4

Integrated e-Health (Electronic Health) for HIV and Substance Use Disorders in Justice Involved Women

Opioid-use DisorderHIVeHealth
Yale University250 enrolled2 locationsNCT05547048
Recruiting
Phase 4

Bazedoxifene -Treatment for Women With Schizophrenia

SchizophreniaSchizo Affective DisorderSchizophreniform Disorders
The Alfred160 enrolled1 locationNCT04113993
Recruiting
Phase 4

Metabolic Effects of Adjunctive Lumateperone Treatment in Clozapine-Treated Patients With Schizophrenia

SchizophreniaSchizo Affective Disorder
University of Massachusetts, Worcester50 enrolled1 locationNCT06174116
Recruiting
Phase 4

Medication Treatment of ADHD in Pediatric Epilepsy

ADHD - Attention Deficit Disorder With Hyperactivity
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.25 enrolled1 locationNCT07594652
Recruiting
Phase 4

Biomarker Validation in Motor System Physiology in Attention Deficit Hyperactivity Disorder

Attention Deficit Hyperactivity Disorder Combined
Donald Gilbert, MD, MS, FAAN, FAAP214 enrolled2 locationsNCT04421248