RecruitingPhase 4NCT04811014

Young Houston Emergency Opioid Engagement System

Houston Emergency Engagement System for Youths and Adolescents


Sponsor

The University of Texas Health Science Center, Houston

Enrollment

250 participants

Start Date

Apr 19, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The Houston Emergency Response Opioid Engagement System for Youths and Adolescents (Young HEROES) is a community-based research program integrating assertive outreach, medication for opioid use disorder (MOUD), behavioral counseling, and peer recovery support. The objective is to compare differences in engagement and retention in treatment for individuals with opioid use disorder. The investigators also intend to understand the prevalence of opioid overdoses and OUD among youth in Houston.


Eligibility

Min Age: 13 YearsMax Age: 17 Years

Inclusion Criteria6

  • In otherwise good health based on physician assessment and medical history
  • Drug screen positive for opioids
  • Patients express a willingness to stop opioid use
  • Meet Diagnostic and Statistical Manual of Mental Disorders - Text Revision (DSM-IV-TR) criteria for opioid dependence
  • Patients must be able to speak English
  • Be agreeable to and capable of signing the informed consent and assent (parent or guardian must consent, minor must assent)

Exclusion Criteria6

  • Non-English-speaking patients
  • Have a known sensitivity to buprenorphine or naloxone
  • Be physiologically dependent on alcohol, benzodiazepines, or other drugs of abuse that require immediate medical attention. Other substance use diagnoses are not exclusionary.
  • Have a medical condition that would, in the opinion of the study physician, make participation medically hazardous, including unstable cardiovascular disease, neurological deficits, trauma, acute hepatitis, stroke, and liver or renal disease)
  • Be acutely psychotic, severely depressed, and in need of inpatient treatment, or is an immediate suicide risk
  • Be a nursing or pregnant female

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Interventions

DRUGBuprenorphine, Naloxone Drug Combination

8mg of buprenorphine/2mg of naloxone to initiate MOUD treatment and bridge, if necessary, until referral to MOUD clinic can be made for ongoing treatment

BEHAVIORALIndividual Counseling

One-on-one counseling with a licensed chemical dependency counselor

BEHAVIORALPeer Recovery Support Services

24/7 support from our team of certified peer recovery support specialists to assist with emotional support and case management

BEHAVIORALSupport Group

Referrals to youth-focused support groups and eventual creation of in-house youth-focused support groups

BEHAVIORALReferral to Medication Management

Study staff will refer patients to long-term MOUD providers in the community

BEHAVIORALAssertive Outreach

The investigators will conduct weekly outreach to youths who experienced an opioid overdose and attempt to initiate treatment. Outreach is completed by a paramedic and peer coach.


Locations(1)

The University of Texas Health Science Center at Houston

Houston, Texas, United States

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NCT04811014


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