Phase 3 DM Clinical Trials

18 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 118 of 18 trials

Recruiting
Phase 3

Neoadjuvant/Adjuvant AK104 in Microsatellite Instability-high or Mismatch Repair-deficient, Resectable Colon Cancer

MSI-H/dMMR Colorectal CancerResectable Colon Cancer
Akeso386 enrolled1 locationNCT07412613
Recruiting
Phase 3

Efficacy, Safety, and Tolerability of Zeleciment Basivarsen (DYNE-101) in Participants With Myotonic Dystrophy Type 1

Myotonic DystrophyDM1Steinert Disease+2 more
Dyne Therapeutics150 enrolled4 locationsNCT07486934
Recruiting
Phase 3

CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

Diabetic Macular Edema (DME)Diabetic Macular EdemaDME
EyePoint Pharmaceuticals, Inc.240 enrolled38 locationsNCT07449923
Recruiting
Phase 3

COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME

Diabetic Macular Edema (DME)Diabetic Macular EdemaDME
EyePoint Pharmaceuticals, Inc.240 enrolled39 locationsNCT07449936
Recruiting
Phase 3

Efficacy Evaluation Study of BAT5906 and Lucentis® in Patients With Diabetic Macular Edema

Diabetic Macular Edema (DME)
Bio-Thera Solutions406 enrolled50 locationsNCT07515079
Recruiting
Phase 3

A Study to Evaluate the Effect of Obicetrapib/Ezetimibe 10 mg Fixed-Dose Combination or Obicetrapib 10 mg Daily on Top of Guideline-Recommended Lipid-Lowering Therapy in Participants With Type 2 Diabetes and/or Metabolic Syndrome

Type 2 Diabetes (T2DM)LipidemiaMetabolic Syndrome (MetS)
NewAmsterdam Pharma300 enrolled20 locationsNCT07219602
Recruiting
Phase 3

Efficacy and Safety of a Botanical Total Coumarin (TC) Cream in Treating Patients With Psoriasis Vulgaris (PLANTCOAT-III)

Psoriasis VulgarisTopical AdministrationPhase III
Psoriasis Research Institute of Guangzhou300 enrolled1 locationNCT07426120
Recruiting
Phase 2Phase 3

Effect of Interferon Gamma as a Treatment for Post-aggressive Immunosuppression in Intensive Care Units, a Randomized Bayesian Double-blind Controlled Trial Versus Placebo

Post-aggressive ImmunosuppressionAdult Patients Admitted to Intensive Care With Initial Severity (SOFA of the First 24 Hours Post-admission ≥ 6Adult Under Mechanical Ventilation, and Presenting an mHLA-DR Less Than 8,000AB/C
Assistance Publique - Hôpitaux de Paris170 enrolled2 locationsNCT06694740
Recruiting
Phase 3

A Study of BGM0504 in Participants With Type 2 Diabetes in Indonesia

Type 2 Diabetes (T2DM)
BrightGene Bio-Medical Technology Co., Ltd.477 enrolled4 locationsNCT07064486
Recruiting
Phase 3

Efficacy and Safety of Add-On Therapy With Empagliflozin in Patients With Type 2 Diabetes on a Background of Alogliptin and Metformin

Diabete Type 2T2DMDM
Celltrion171 enrolled1 locationNCT07093476
Recruiting
Phase 3

PRODIGE 90 - (FFCD 2204) Neoadjuvant Dostarlimab with Short Course Radiotherapy in a Watch-and-wait Strategy for Microsatellite Unstable or Mismatch Repair-deficient Locally Advanced Rectal Cancer Patients

Rectal Adenocarcinoma with Mismatch-repair Deficient (dMMR)/ Microsatellite Instability-high (MSI-H)
Centre Hospitalier Universitaire Dijon68 enrolled1 locationNCT06762405
Recruiting
Phase 3

A Study of BGM0504 in Participants with Type 2 Diabetes

Type 2 Diabetes Mellitus (T2DM)
BrightGene Bio-Medical Technology Co., Ltd.537 enrolled1 locationNCT06716216
Recruiting
Phase 3

A Study of BGM0504 in Poorly Controlled Type 2 Diabetes Patients Only Through Diet and Exercise

Type 2 Diabetes Mellitus (T2DM)
BrightGene Bio-Medical Technology Co., Ltd.207 enrolled1 locationNCT06716203
Recruiting
Phase 3

RCT Glargine vs NPH for Treatment of DM in Pregnancy

Type 2 Diabetes Mellitus (T2DM)Diabetes Mellitus in PregnancyGestational Diabetes Mellitus, Class A2
Loyola University160 enrolled1 locationNCT06619301
Recruiting
Phase 3

The Efficacy of Intravenous Pulse in Attaining Remission in Refractory Juvenile Idiopathic Arthritis

Refractory Juvenile Idiopathic Arthritis (Despite 2 DMARDs Still Active)
Sohag University215 enrolled1 locationNCT06463379
Recruiting
Phase 3

Impact of P53 and SIRT1 in Type 2 Diabetes

DM
Sherief Abd-Elsalam90 enrolled1 locationNCT03925714
Recruiting
Phase 3

Mifepristone ovarian function study

The effect of administering a progestogen receptor modulator with or without oestrogen on the ovarian function and quality of cervical mucus in women using the progestogen-only sub-dermal contraceptive, Implanon.
FPA Health40 enrolled1 locationACTRN12605000698673
Active
Phase 3

Randomised controlled trial of maintenance fluids in paediatric intensive care.

Children admitted to paediatric intensive care (PICU)
Women's and Children's Hospital Adelaide. Not sponsored financially.48 enrolled1 locationACTRN12605000061639