Phase 2 Down Syndrome Clinical Trials
8 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–8 of 8 trials
Recruiting
Phase 2
AEF0217 in Participants With Down Syndrome
Down Syndrome (Trisomy 21)
Aelis Farma188 enrolled10 locationsNCT07334912
Recruiting
Phase 1Phase 2
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaMyelodysplastic Syndrome+5 more
PedAL BCU, LLC960 enrolled182 locationsNCT04726241
Recruiting
Phase 2
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
Recurrent B Acute Lymphoblastic LeukemiaDown Syndrome
National Cancer Institute (NCI)461 enrolled215 locationsNCT04546399
Recruiting
Phase 2
Down Syndrome Obstructive Sleep Apnea
Obstructive Sleep ApneaDown Syndrome
Brigham and Women's Hospital230 enrolled7 locationsNCT06043440
Recruiting
Phase 2
Medications for Obstructive Sleep Apnea to Improve Cognition in Children With Down Syndrome
Obstructive Sleep ApneaDown Syndrome
University of Arizona36 enrolled1 locationNCT05933603
Recruiting
Phase 2
Efficacy of Bumetanide to Improve Cognitive Functions in Down Syndrome
Down Syndrome
Stefano Vicari64 enrolled1 locationNCT06465823
Recruiting
Phase 2Phase 3
GnRH Therapy on Cognition in Down Syndrome
Cognitive DeclineAlzheimer Disease, Early OnsetDown Syndrome+1 more
Nelly Pitteloud56 enrolled1 locationNCT04390646
Recruiting
Phase 2
ASIA Down Syndrome Acute Lymphoblastic Leukemia 2016
Acute Lymphoblastic LeukemiaChildhood CancerDown Syndrome
National Hospital Organization Nagoya Medical Center60 enrolled10 locationsNCT03286634