Dysfunction Clinical Trials in Boston, Massachusetts

16 recruitingBoston, Massachusetts

Showing 116 of 16 trials

Recruiting
Phase 2Phase 3

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

Heart FailureLeft Ventricular Systolic Dysfunction
Merck Sharp & Dohme LLC342 enrolled105 locationsNCT05714085
Recruiting
Phase 3

A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

Left Ventricular Systolic DysfunctionHeart Failure (Pediatric)
Bayer111 enrolled133 locationsNCT07188805
Recruiting
Not Applicable

A Novel Digital Application (SHIFT) to Improve Outcomes for Hematopoietic Stem Cell Transplant Survivors

Sexual DysfunctionStem Cell Transplant ComplicationsBone Marrow Transplant Complications
Massachusetts General Hospital300 enrolled3 locationsNCT06541002
Recruiting
Not Applicable

COMPASSION S3 - Evaluation of the SAPIEN 3 Transcatheter Heart Valve in Patients With Pulmonary Valve Dysfunction

Complex Congenital Heart DefectDysfunctional RVOT ConduitPulmonary Valve Insufficiency+1 more
Edwards Lifesciences108 enrolled25 locationsNCT02744677
Recruiting
Not Applicable

SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study

Chronic Kidney DiseasesArteriovenous FistulaVascular Access Complication+7 more
VenoStent600 enrolled28 locationsNCT06001827
Recruiting
Early Phase 1

The Kidney's Response to Exercise in Heat, and the Impact of Vitamin B3 on This Response

Heat StrainHealthy Volunteer StudyKidney Dysfunction
Beth Israel Deaconess Medical Center28 enrolled2 locationsNCT06983730
Recruiting
Not Applicable

Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia

Mobility LimitationDementiaAlzheimer Disease+2 more
Hebrew SeniorLife144 enrolled1 locationNCT05661084
Recruiting
Phase 4

Gastrointestinal Dysmotility on Aspiration Risk

Esophageal Motility DisordersGastric Motor Dysfunction
Boston Children's Hospital120 enrolled1 locationNCT05455359
Recruiting
Not Applicable

Effect of Endoscopic Sleeve Gastroplasty in Patients With Obesity and MASH: A Randomized Controlled Trial

Insulin Sensitivity/ResistanceObesityInsulin Resistance+14 more
Pichamol Jirapinyo, MD, MPH132 enrolled2 locationsNCT06138821
Recruiting

The Impact of Renal Transplant on Coronary Microvascular Function Among Patients With Advanced Chronic Kidney Disease

Kidney TransplantChronic Kidney DiseaseInflammation+1 more
Brigham and Women's Hospital80 enrolled1 locationNCT07222683
Recruiting

CEReBral AutorEgulation in Non-cardiac SuRgery and Relationship to Postoperative DeliriUm State

Perioperative/Postoperative ComplicationsPostoperative DeliriumPostoperative Cognitive Dysfunction+1 more
Beth Israel Deaconess Medical Center100 enrolled1 locationNCT06133842
Recruiting
Phase 2

Improving Coronary Vascular Health in Women

Metabolic DiseaseHIV-1-infectionCoronary Microvascular Dysfunction
Massachusetts General Hospital80 enrolled1 locationNCT06843902
Recruiting
Not Applicable

Treatment of Pulmonary Arterial Hypertension Using the Aria CV Pulmonary Hypertension System

Pulmonary HypertensionPulmonary Arterial HypertensionRight Heart Dysfunction
Aria CV, Inc30 enrolled12 locationsNCT04555161
Recruiting

A Retrospective and Prospective Natural History of Genetic Vasculopathies

Multisystemic Smooth Muscle Dysfunction SyndromeACTA2
Massachusetts General Hospital50 enrolled1 locationNCT06552052
Recruiting

Impella RP Flex with Smart Assist

Right Ventricular (RV) Dysfunction
Abiomed Inc.200 enrolled31 locationsNCT06637644
Recruiting

Identification of Genomic Predictors of Adverse Events After Cardiac Surgery

Heart FailureAtrial FibrillationGenetic Predisposition to Disease+2 more
Brigham and Women's Hospital4,000 enrolled3 locationsNCT01258231