Phase 1 Dysplasia Clinical Trials
14 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–14 of 14 trials
Recruiting
Phase 1
Autologous T Cells Transduced With Retroviral Vectors Expressing TCRs for Participant-specific Neoantigens in Patients With Hematologic Malignancies
Leukemia, Lymphocytic, AcuteBlood CancerMyeloid Leukemia, Acute+8 more
National Cancer Institute (NCI)86 enrolled1 locationNCT06904066
Recruiting
Phase 1
Inhaled Ciclesonide Study in Preterm Infants
Bronchopulmonary Dysplasia
Venkatesh Sampath30 enrolled1 locationNCT06589245
Recruiting
Phase 1Phase 2
PK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary Dysplasia
Critical IllnessBronchopulmonary Dysplasia (BPD)Premature Births
Duke University28 enrolled4 locationsNCT07101640
Recruiting
Phase 1Phase 2
Topical Imiquimod Treatment of Oral Dysplasia
Oral Dysplasia
University of Southern California20 enrolled1 locationNCT07210775
Recruiting
Phase 1
Fenretinide Mucoadhesive Patch: Evaluation of Oral Cancer Prevention Efficacy in Adults With Premalignant Oral Lesions.
Oral LeukoplakiaOral Dysplasia
Ohio State University25 enrolled1 locationNCT07149220
Recruiting
Phase 1Phase 2
Astroscape: A Study of Radiprodil on Safety, Tolerability, Pharmacokinetics, and Effect on Seizures and Behavioral Symptoms in Patients With TSC or FCD Type II
Tuberous Sclerosis ComplexFocal Cortical Dysplasia
GRIN Therapeutics, Inc.30 enrolled20 locationsNCT06392009
Recruiting
Phase 1
Study of VEGF-A Targeting NIR-II Fluorescence Endoscopy in the Gastrointestinal Tract
DysplasiaGastrointestinal CarcinomaGastrointestinal Polyp
Institute of Automation, Chinese Academy of Sciences30 enrolled1 locationNCT06430372
Recruiting
Phase 1Phase 2
Safety and Efficacy of Umbilical Cord-derived Mesenchymal Stem Cell(MSC) Transplantation in the Treatment of Bronchopulmonary Dysplasia(BPD) in Premature Infants
BPD - Bronchopulmonary Dysplasia
The Children's Hospital of Zhejiang University School of Medicine10 enrolled1 locationNCT06788470
Recruiting
Phase 1Phase 2
Safety and Efficacy of MSC-EVs in the Prevention of BPD in Extremely Preterm Infants
Bronchopulmonary Dysplasia
EXO Biologics S.A.265 enrolled8 locationsNCT06279741
Recruiting
Phase 1Phase 2
Different Levels of BiPAP
Bronchopulmonary Dysplasia
King's College Hospital NHS Trust21 enrolled1 locationNCT06421519
Recruiting
Phase 1
Mesenchymal Stem Cells for Prevention of Bronchopulmonary Dysplasia in Infants
Bronchopulmonary Dysplasia
Meridigen Biotech Co., Ltd.9 enrolled1 locationNCT03631420
Completed
Phase 1
Randomized, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability and Pharmacokinetics of KER-047 Administered to Healthy Male Volunteers and Postmenopausal Female Volunteers
Fibrodysplasia ossificans progressiva
Keros Therapeutics, Australia Pty Ltd141 enrolled1 locationACTRN12619000319178
Completed
Phase 1
A Trial Evaluating Safety, Tolerability and Pharmacokinetics of Subcutaneous Single Doses of ACP-015 in Healthy Adult Male Subjects.
AchondroplasiaThanatophoric DysplasiaSkeletal Dysplasia in Children+4 more
Ascendis Pharma Growth Disorders A/S60 enrolled1 locationACTRN12618001157268
Recruiting
Phase 1
Human Amnion Epithelial Cells for Prevention of Bronchopulmonary Dysplasia in Preterm Infants: A Safety Study
Bronchopulmonary DysplasiaExtremely preterm birth
Monash Health24 enrolled2 locationsACTRN12618000920291