Phase 3 Early Stage Clinical Trials

8 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 18 of 8 trials

Recruiting
Phase 3

Pembrolizumab vs. Observation in People With Triple-negative Breast Cancer Who Had a Pathologic Complete Response After Chemotherapy Plus Pembrolizumab

Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8Anatomic Stage IIIB Breast Cancer AJCC v8+1 more
Alliance for Clinical Trials in Oncology1,295 enrolled838 locationsNCT05812807
Recruiting
Phase 3

Early Stage Follicular LymphOma and RadioTherapy PLUS Anti-CD20 Antibody

Early Stage Follicular Lymphoma WHO Grade 1/2 or 3a
Heidelberg University100 enrolled12 locationsNCT05045664
Recruiting
Phase 3

A Study to Assess the Efficacy and Safety of Zipalertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB-IIIA NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection

Lung CancerEGFRNSCLC, Stage IB-IIIA+5 more
Taiho Oncology, Inc.360 enrolled253 locationsNCT07128199
Recruiting
Phase 2Phase 3

Continuous Positive Airway Pressure (CPAP) Assisted Radiotherapy in Breast Cancer

Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Universitaire Ziekenhuizen KU Leuven53 enrolled1 locationNCT07373782
Recruiting
Phase 3

A Study to Determine the Efficacy of a Digital Self-management Support Tool to Improve the Quality of Life During Adjuvant HOrmonal Therapy for Patients With Early Breast Cancer

Breast CancerBreast Cancer Early Stage Breast Cancer (Stage 1-3)
Gustave Roussy, Cancer Campus, Grand Paris180 enrolled1 locationNCT06781996
Recruiting
Phase 3

Shorter Chemo-Immunotherapy Without Anthracycline Drugs for Early-Stage Triple Negative Breast Cancer

Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage IIIA Breast Cancer AJCC v8+2 more
SWOG Cancer Research Network2,400 enrolled963 locationsNCT05929768
Recruiting
Phase 3

Adjuvant Trastuzumab Plus Neratinib in Hormone Receptor-Positive/Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer After Neoadjuvant Trastuzumab Plus Pertuzumab

HER2-positive Breast CancerEarly Stage Breast CancerAdjuvant Treatment After Trastuzumab+2 more
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University300 enrolled1 locationNCT05760612
Completed
Phase 3

SWOG 0230 / IBCSG 34-05

Ovarian function in premenopasual women with early stage, hormone-receptor negative breast cancer
Australia and New Zealand Breast Cancer Trials Group416 enrolled1 locationACTRN12606000075583