Phase 3 Ejection Fraction Clinical Trials
12 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–12 of 12 trials
Recruiting
Phase 3
Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
ObesityHeart Failure With Preserved Ejection FractionHeart Failure With Mildly Reduced Ejection Fraction
Amgen5,056 enrolled603 locationsNCT07037459
Recruiting
Phase 3
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
Heart FailureHeart Failure With Reduced Ejection Fraction
Cytokinetics1,800 enrolled185 locationsNCT06736574
Recruiting
Phase 3
Selenium Intervention Registry Randomized Trial in Heart Failure
Cognitive functioningHeart FailureHeart Failure and Reduced Ejection Fraction+4 more
Skane University Hospital4,326 enrolled11 locationsNCT07543562
Recruiting
Phase 2Phase 3
Withdrawal of Treatment for Heart Failure Patients With Recovery From Tachycardia-induced Cardiomyopathy
Heart Failure With Reduced Ejection FractionHeart Rhythm Disorder
Herlev and Gentofte Hospital348 enrolled1 locationNCT06128980
Recruiting
Phase 2Phase 3
Tailored Exercise Training Study Among Adults With HFpEF
Diabetic CardiomyopathiesHFpEF - Heart Failure With Preserved Ejection Fraction
University of Texas Southwestern Medical Center120 enrolled1 locationNCT07223242
Recruiting
Phase 2Phase 3
A Randomised, Controlled Trial of a Low-energy Diet for Improving Functional Status in Heart Failure With PRESERVED Ejection Fraction Preserved Ejection Fraction
Diabetes Mellitus, Type 2Heart Failure With Preserved Ejection FractionHeart Failure, Diastolic+2 more
University of Leicester63 enrolled3 locationsNCT05887271
Recruiting
Phase 3
The Effect of Sacubitril/valsartan Versus Ramipril on Left Ventricular Function and Remodeling in Patients with Ischemic Heart Failure with Mid-range Ejection Fraction
Heart Failure with Moderately Reduced Ejection Fraction
John Paul II Hospital, Krakow666 enrolled1 locationNCT05508035
Recruiting
Phase 3
Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction
Heart Failure With Preserved Ejection Fraction
Uppsala University2,000 enrolled78 locationsNCT02901184
Recruiting
Phase 3
A Trial to Evaluate the Safety and Efficacy of Pulmonary Artery Denervation for the Treatment of Pulmonary Hypertension Associated With Left Heart Failure
Heart FailureCardiovascular DiseasesHypertension+5 more
Pulnovo Medical (Wuxi) Co., Ltd.264 enrolled1 locationNCT05824923
Recruiting
Phase 2Phase 3
Effect of Weight Loss on Physical and Cardiac Performance in People With Obesity and Heart Failure
ObesityWeight LossHeart Failure With Reduced Ejection Fraction+1 more
Jens D Hove, MD,PHD100 enrolled1 locationNCT06423599
Recruiting
Phase 3
S086 Tablets for Chronic Heart Failure With Reduced Ejection Fraction
Chronic Heart Failure With Reduced Ejection Fraction
Shenzhen People's Hospital5 enrolled1 locationNCT05553886
Completed
Phase 3Phase 4
Use of exercise and medical therapies to improve cardiac function among patients with exertional shortness of breath due to lung congestion
Diastolic dysfunction, heart failure with preserved ejection fraction (HFpEF)
University of Queensland150 enrolled1 locationACTRN12610001087044