Phase 2 Estrogen Receptor-positive Breast Cancer Clinical Trials

8 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 18 of 8 trials

Recruiting
Phase 2

PhII Randomized CAPecitabine + ELAcestrant vs. Capecitabine Alone in ER+ Breast Cancer (CAPELA)

Breast CancerMetastatic Breast CancerBreast Neoplasms+6 more
Kristina A. Fanucci297 enrolled1 locationNCT07222215
Recruiting
Phase 2

Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies

Breast CancerTriple-Negative Breast CancerMetastatic Breast Cancer+2 more
UNC Lineberger Comprehensive Cancer Center700 enrolled2 locationsNCT07340541
Recruiting
Phase 2

Adaptive Therapy With Capecitabine for Treatment of Metastatic ER Positive, HER2 Negative Breast Cancer

Metastatic Breast CancerAnatomic Stage IV Breast Cancer AJCC v8Estrogen Receptor-positive Breast Cancer+1 more
Mayo Clinic35 enrolled1 locationNCT06525766
Recruiting
Phase 2

(Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer

Breast NeoplasmsHER2-negative Breast CancerInvasive Breast Cancer+1 more
Atossa Therapeutics, Inc.87 enrolled15 locationsNCT05607004
Recruiting
Phase 2

Elacestrant vs Elacestrant Plus a CDK4/6 Inhibitor in Patients With ERpositive/HER2-negative Advanced or Metastatic Breast Cancer

Metastatic Breast CancerEstrogen Receptor-positive Breast CancerHER2/Neu-Negative Breast Cancer+1 more
Northwestern University174 enrolled1 locationNCT06062498
Recruiting
Phase 2

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Breast CancerBreast Cancer MetastaticBreast Cancer Female+3 more
Dana-Farber Cancer Institute72 enrolled1 locationNCT06439693
Recruiting
Phase 2

Ketorolac and Pregabalin Effects on breaSt Cancer (KePreSt)

Estrogen Receptor-positive Breast CancerEarly Stage Breast Cancer
Jules Bordet Institute112 enrolled1 locationNCT06150898
Recruiting
Phase 2

Correlation of Clinical Response to Pathologic Response in Patients With Early Breast Cancer

Breast CancerTriple-Negative Breast CancerBreast Cancer Female+8 more
Baylor Breast Care Center185 enrolled2 locationsNCT05020860