Phase 2 Ewing Sarcoma Clinical Trials
14 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–14 of 14 trials
Recruiting
Phase 1Phase 2
Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma
Recurrent Malignant Solid NeoplasmRefractory Malignant Solid NeoplasmRecurrent Solid Tumor+19 more
St. Jude Children's Research Hospital90 enrolled10 locationsNCT04901702
Recruiting
Phase 1Phase 2
Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas
OsteosarcomaEwing SarcomaNeuroblastoma+4 more
Milton S. Hershey Medical Center289 enrolled10 locationsNCT06465199
Recruiting
Phase 1Phase 2
Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors
OsteosarcomaEwing SarcomaNeuroblastoma+2 more
Milton S. Hershey Medical Center104 enrolled21 locationsNCT06541262
Recruiting
Phase 1Phase 2
Lurbinectedin in FET-Fused Tumors
Ewing SarcomaPediatric CancerDesmoplastic Small Round Cell Tumor+1 more
Children's Hospital of Philadelphia63 enrolled6 locationsNCT05918640
Recruiting
Phase 1Phase 2
Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors
OsteosarcomaEwing SarcomaNeuroblastoma+10 more
University of Florida27 enrolled1 locationNCT06625190
Recruiting
Phase 1Phase 2
Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
Ovarian CarcinomaColorectal CarcinomaMelanoma+19 more
Children's Oncology Group147 enrolled21 locationsNCT04851119
Recruiting
Phase 1Phase 2
Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma
Ewing SarcomaRefractory Ewing SarcomaRelapsed Ewing Sarcoma
Jazz Pharmaceuticals60 enrolled15 locationsNCT05734066
Recruiting
Phase 2
Phase II Study of Irinotecan Liposome (II) Combined With Temozolomide and Fluzoparib in Recurrent or Metastatic Ewing Sarcoma
Ewing Sarcoma
Sun Yat-sen University29 enrolled1 locationNCT06827717
Recruiting
Phase 2
To Evaluate the Efficacy and Safety of Naxitamab in Patients With Refractory Ewing's Sarcoma (Butterfly)
Ewing Sarcoma
Anna Raciborska24 enrolled2 locationsNCT05968768
Recruiting
Phase 1Phase 2
Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision)
Ewing SarcomaRhabdomyosarcomaSynovial Sarcoma
University Hospital Tuebingen30 enrolled4 locationsNCT06094101
Recruiting
Phase 2
A Prospective, Randomized, Controlled Clinical Study on the Prevention of Chemotherapy Related Myelosuppression in Patients with Ewing's Sarcoma Using Trilaciclib
Ewing SarcomaMyelosuppression
Fudan University22 enrolled1 locationNCT06699472
Recruiting
Phase 2
A Study of KC1036 in Adolescents With Advanced Ewing Sarcoma
Ewing Sarcoma
Beijing Konruns Pharmaceutical Co., Ltd.30 enrolled1 locationNCT06564272
Recruiting
Phase 2
Metformin as Maintenance Therapy in Patients With Bone Sarcoma and High Risk of Relapse
OsteosarcomaEwing Sarcoma
Istituto Ortopedico Rizzoli67 enrolled1 locationNCT04758000
Recruiting
Phase 2Phase 3
rEECur: Chemotherapy for the treatment of recurrent and primary refractory Ewing sarcoma
Ewing Sarcoma
University of Birmingham600 enrolled28 locationsACTRN12618001825246