Phase 1 Extensive-stage Small-cell Lung Cancer Clinical Trials

7 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 17 of 7 trials

Recruiting
Phase 1

A Study of Valemetostat in Combination With Atezolizumab in People With Lung Cancer

Extensive-stage Small-cell Lung Cancer
Memorial Sloan Kettering Cancer Center24 enrolled7 locationsNCT06807632
Recruiting
Phase 1

Subcutaneous Tarlatamab in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-308)

Extensive-stage Small-cell Lung Cancer
Amgen220 enrolled31 locationsNCT06598306
Recruiting
Phase 1

A Study of Tarlatamab in Combination With AB248 in Participants With Extensive Stage Small Cell Lung Cancer (DeLLphi-311)

Extensive-stage Small-cell Lung Cancer
Amgen380 enrolled19 locationsNCT07037758
Recruiting
Phase 1Phase 2

Safety and Tolerability of LDRT+Sugemalimab+Chemotherapy+Olaparib for First-Line Treatment of SLFN-11 Positive ES-SCLC

Lung CancerExtensive-stage Small-cell Lung Cancer
Sichuan University45 enrolled1 locationNCT06217757
Recruiting
Phase 1

A PHASE I STUDY OF ALPS12 IN PATIENTS WITH EXTENSIVE STAGE SMALL CELL LUNG CANCER

Extensive-stage Small-cell Lung Cancer
Chugai Pharmaceutical122 enrolled6 locationsNCT07107490
Recruiting
Phase 1Phase 2

A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

Extensive-stage Small-cell Lung Cancer
Daiichi Sankyo123 enrolled58 locationsNCT06362252
Recruiting
Phase 1Phase 2

Radiotherapy to All Residual Lesions After Chemoimmunotherapy

Extensive-stage Small-cell Lung Cancer
Anhui Provincial Hospital150 enrolled1 locationNCT06479473