Phase 2 Extensive-stage Small-cell Lung Cancer Clinical Trials

13 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 113 of 13 trials

Recruiting
Phase 2

Chemo-Immunotherapy Followed by Durvalumab and Ceralasertib in Treatment Naïve Patients With Extensive Stage Small Cell Lung Cancer

Extensive-stage Small-cell Lung Cancer
Muhammad Furqan30 enrolled5 locationsNCT04699838
Recruiting
Phase 2

Maintenance Lurbinectedin in Combination With Serplulimab for Patients With ES-SCLC

Extensive-stage Small-cell Lung Cancer
Guangzhou Institute of Respiratory Disease30 enrolled1 locationNCT06497530
Recruiting
Phase 1Phase 2

Safety and Tolerability of LDRT+Sugemalimab+Chemotherapy+Olaparib for First-Line Treatment of SLFN-11 Positive ES-SCLC

Lung CancerExtensive-stage Small-cell Lung Cancer
Sichuan University45 enrolled1 locationNCT06217757
Recruiting
Phase 2

MOnaliZumab in Combination With durvAlumab (MEDI4736) for tRreatmenT of Small Cell Lung Cancer

SCLCSmall Cell Lung CancerLimited Stage Small Cell Lung Cancer+1 more
Hirva Mamdani84 enrolled4 locationsNCT05903092
Recruiting
Phase 2

Tislelizumab Combined With Chemotherapy and Thoracic Radiotherapy in ES-SCLC

Extensive-stage Small-cell Lung Cancer
Second Hospital of Shanxi Medical University40 enrolled6 locationsNCT06536868
Recruiting
Phase 2

Durvalumab and Ablative Radiation in Small Cell Lung Cancer (DARES)

Lung CancerSmall Cell Lung CancerExtensive-stage Small-cell Lung Cancer
University of Chicago49 enrolled2 locationsNCT05068232
Recruiting
Phase 1Phase 2

A Study of I-DXd in Combination With Atezolizumab With or Without Carboplatin as First-Line Induction or Maintenance in Subjects With Extensive Stage-Small Cell Lung Cancer (IDeate-Lung03)

Extensive-stage Small-cell Lung Cancer
Daiichi Sankyo123 enrolled58 locationsNCT06362252
Recruiting
Phase 2

Study of Bevacizumab in Combination With Chemoimmunotherapy and Atezolizumab in Patients With Extensive Stage Small Cell Lung Cancer and Liver Metastases

Liver MetastasesExtensive-stage Small-cell Lung Cancer
Kamya Sankar39 enrolled3 locationsNCT05588388
Recruiting
Phase 2

A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Extensive-stage Small Cell Lung Cancer

Extensive-stage Small-cell Lung Cancer
Sichuan Baili Pharmaceutical Co., Ltd.66 enrolled1 locationNCT06437509
Recruiting
Phase 2

First-line Treatment for ES-SCLC with Chemotherapy Combined with PD-1/PD-L1 Inhibitor Sequential Thoracic Radiotherapy

Extensive-stage Small-cell Lung Cancer
Henan Cancer Hospital47 enrolled1 locationNCT06586697
Recruiting
Phase 1Phase 2

Radiotherapy to All Residual Lesions After Chemoimmunotherapy

Extensive-stage Small-cell Lung Cancer
Anhui Provincial Hospital150 enrolled1 locationNCT06479473
Recruiting
Phase 2

Study of Low-Dose Radiotherapy Concurrent Chemotherapy With Serplulimab for Patients With ES-SCLC

Extensive-stage Small-cell Lung Cancer
Sichuan University61 enrolled8 locationsNCT05765825
Recruiting
Phase 2

Durvalumab With Consolidative Radiochemotherapy and Ablative Stereotactic Radiotherapy in Oligometastatic ES-SCLC

Extensive-stage Small-cell Lung Cancer
Universität des Saarlandes43 enrolled5 locationsNCT06223711