Phase 1 Eye disease Clinical Trials
10 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–10 of 10 trials
Recruiting
Phase 1Phase 2
A Study of AMG 732 in Healthy Participants and Participants With Thyroid Eye Disease
Thyroid Eye Disease
Amgen88 enrolled30 locationsNCT06401044
Recruiting
Phase 1
A Study of GenSci098 in Subjects With Active Thyroid Eye Disease
SafetyTolerabilityGenSci098+1 more
Changchun GeneScience Pharmaceutical Co., Ltd.76 enrolled1 locationNCT06569758
Recruiting
Phase 1Phase 2
A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001
Retinal DegenerationRetinal DiseaseRetinal Dystrophies+2 more
PYC Therapeutics16 enrolled6 locationsNCT06852963
Recruiting
Phase 1
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for NAION
Retinitis PigmentosaMacular DegenerationDiabetic Retinopathy+3 more
The Foundation for Orthopaedics and Regenerative Medicine20 enrolled2 locationsNCT05147701
Recruiting
Phase 1
MAD of IVT VP-001 in PRPF31 Mutation-Associated Retinal Dystrophy Subjects (Wallaby)
Retinal DegenerationRetinal DiseaseEye Diseases+2 more
PYC Therapeutics12 enrolled5 locationsNCT06455826
Completed
Phase 1
ILYX-002 Pharmacokinetics in Healthy Volunteers
Dry-Eye Disease
Iolyx Australia Pty Ltd16 enrolled1 locationACTRN12624001355561
Recruiting
Phase 1Phase 2
Safety & Efficacy of Eyecyte-RPE™ in Patients With Geographic Atrophy Secondary to Dry Age-related Macular Degeneration.
Geographic AtrophyAge-Related Macular DegenerationMacular Degeneration+2 more
Eyestem Research Pvt. Ltd.54 enrolled3 locationsNCT06394232
Completed
Phase 1
Dosing Study of the V501 Product - Protocol 503: An Efficacy Study comparing two Doses of the V501 Product in Patients with certain Anterior Segment Eye Diseases
Anterior segment eye disease
ForSight VISION5, Inc50 enrolled1 locationACTRN12612000960853
Completed
Phase 1
Pilot Study of the V501 Product - Protocol 502: A pilot study of the ForSight Ocular System on Safety and Efficacy in Anterior Segment Eye Disease in Latvia
Anterior segment eye disease
ForSight VISION5, Inc30 enrolled1 locationACTRN12612000365864
Active
Phase 1
Pilot Study of the V501 Product - Protocol 501: A pilot study of the ForSight Ocular System on Safety and Efficacy in Anterior Segment Eye Disease in Australia
Anterior segment eye disease
ForSight VISION5, Inc30 enrolled1 locationACTRN12612000362897