RecruitingPhase 1Phase 2NCT07404111

A Study of VV-14305 for the Treatment of Thyroid Eye Disease

An Adaptive Phase 1/2 MulticenteR Study Evaluating the Safety, Tolerability, Pharmacokinetics and EfficaCy of VV-14305 Delivered Via PeribuLbAr Injection in Patients With Moderate to Severe Thyroid Eye Disease (the RECLAIM Study)


Sponsor

Kriya Therapeutics, Inc.

Enrollment

135 participants

Start Date

May 1, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this study is to evaluate the safety, tolerability, and efficacy of KRIYA-586 (VV-14305) in treating thyroid eye disease (TED).


Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Sham (No Treatment) and VV-14305 for people with thyroid eye disease (ted). The study is currently recruiting participants at 5 locations. People eligible for this study include aged 18 Years to 80 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

GENETICVV-14305

VV-14305 will be administered via peribulbar injection.

OTHERSham (No Treatment)

Sham solution such as Saline


Locations(5)

Kriya Clinical Trial Site

Livonia, Michigan, United States

Kriya Clinical Trial Site

Las Vegas, Nevada, United States

Kriya Clinical Trial Site

Erie, Pennsylvania, United States

Kriya Clinical Trial Site

Auckland, New Zealand

Kriya Clinical Trial Site

Wellington, New Zealand

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

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NCT07404111


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