Phase 3 Eye disease Clinical Trials

12 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 112 of 12 trials

Recruiting
Phase 2Phase 3

A Clinical Study Evaluating Licaminlimab for Dry Eye Disease

Dry Eye Disease (DED)
Oculis160 enrolled10 locationsNCT07548632
Recruiting
Phase 3

Open-Label Extension Study of MHB018A in Subjects With Thyroid Eye Disease

Thyroid Eye Disease (TED)
Minghui Pharmaceutical (Hangzhou) Ltd258 enrolled1 locationNCT07262476
Recruiting
Phase 3

MHB018A Treatment in Patients With Chronic Thyroid Eye Disease

Thyroid Eye Disease (TED)
Minghui Pharmaceutical (Hangzhou) Ltd150 enrolled1 locationNCT07257185
Recruiting
Phase 3

Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

Sensation DisordersLeber Congenital AmaurosisRetinal Disease+7 more
Laboratoires Thea32 enrolled14 locationsNCT06891443
Recruiting
Phase 3

A Clinical Study to Evaluate the Effect and Side Effect of a New Artificial Tear Formulation (ABBV-444) Compared to Refresh Optive Unit Dose in Adult Participants With Dry Eye Disease

Dry-Eye Disease
AbbVie250 enrolled20 locationsNCT07284381
Recruiting
Phase 3

Vitrectomy, Subretinal Tissue Plasminogen Activator (TPA) and Intravitreal Gas for Submacular Haemorrhage Secondary to Exudative (Wet) Age-related Macular Degeneration (TIGER).

Eye DiseasesMacular Degeneration, WetSub-Macular Hemorrhage
King's College Hospital NHS Trust210 enrolled36 locationsNCT04663750
Recruiting
Phase 3

A Study to Assess the Efficacy and Safety of ZL-1109 in Chinese Participants With Active Thyroid Eye Disease

Thyroid Eye Disease (TED)
Zai Lab (Shanghai) Co., Ltd.99 enrolled27 locationsNCT07211776
Recruiting
Phase 3

A Clinical Study to Evaluate the Efficacy and Safety of IBI311 in Subjects With Inactive Thyroid Eye Disease

Thyroid Eye Disease
Innovent Biologics (Suzhou) Co. Ltd.111 enrolled1 locationNCT07113262
Recruiting
Phase 3

Phase III Clinical Study of Lifitegrast Ophthalmic Solution for the Treatment of Dry Eye Disease

Dry Eye Disease (DED)
Lunan Better Pharmaceutical Co., LTD.820 enrolled1 locationNCT06879782
Recruiting
Phase 2Phase 3

Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED)

Thyroid DiseasesEndocrine System DiseasesThyroid Eye Disease+9 more
Sling Therapeutics, Inc.75 enrolled2 locationsNCT06112340
Recruiting
Phase 3

Effects of Topical Insulin on Corneal Epithelium Healing After Corneal Crosslinking in Patients With Keratoconus

Wound HealEye DiseasesKeratoconus+1 more
University of Campinas, Brazil36 enrolled1 locationNCT06601101
Active
Phase 3

The Fenofibrate And Microvascular Events in Type 1 diabetes Eye: A randomised trial to evaluate the efficacy on retinopathy and safety of fenofibrate in adults with type 1 diabete. A multicentre double-blind placebo-controlled study in Australia and internationally

Eye disease (retinopathy) in type 1 diabetes mellitusDiabetic nephropathy in type 1 diabetes mellitus
NHMRC Clinical Trials Centre, University of Sydney450 enrolled23 locationsACTRN12611000249954