RecruitingPhase 3NCT07753603

Study to Assess Linsitinib in Participants With Moderate to Severe Active Thyroid Eye Disease (TED)

A Phase 3, Randomized, Double-mask, Placebo-controlled Study With Open-label Extension to Evaluate the Efficacy and Safety of Linsitinib in Participants With Moderate to Severe Active Thyroid Eye Disease (TED)


Sponsor

Sling Therapeutics, Inc.

Enrollment

130 participants

Start Date

Aug 4, 2026

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to evaluate the efficacy, safety, and tolerability of linsitinib in participants with moderate to severe Thyroid Eye Disease (TED).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Placebo and a drug called linsitinib for people with graves orbitopathy and thyroid eye disease (ted). The study is currently recruiting participants at 1 location. People eligible for this study include aged 18 Years and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGlinsitinib

150 mg linsitinib is taken twice daily by mouth for 24 weeks

DRUGPlacebo

0 mg placebo taken twice daily by mouth for 24 weeks


Locations(1)

Advancing Research International

Las Vegas, Nevada, United States

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NCT07753603


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