Phase 1 Female Clinical Trials

22 recruitingPhase 1

What is a Phase 1 trial?

Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.

Showing 120 of 22 trials

Recruiting
Phase 1

A Study of ORN252 in Healthy Participants

Healthy Volunteers - Male and Female
Orna Therapeutics, Inc.20 enrolled1 locationNCT07439796
Recruiting
Phase 1Phase 2

ERADICATE: A Phase Ib/II Study of Elacestrant Plus Trastuzumab Deruxtecan in Patients With CDK4/6 Inhibitor and Endocrine-resistant HR+/HER2-low or HER2-ultralow Metastatic Breast Cancer

Breast CancerMetastatic Breast CancerBreast Cancer Female+2 more
Sarah Sammons, MD65 enrolled1 locationNCT07198724
Recruiting
Phase 1

A Study to Evaluate the Safety of Increasing Doses of DF5112 in Healthy Adults

HealthyHealthy ParticipantsHealthy Adult Male+2 more
Dragonfly Therapeutics48 enrolled1 locationNCT07232121
Recruiting
Phase 1

MUC1-Activated T Cells for the Treatment of Relapsed and Resistant Ovarian Cancer

Recurrent Ovarian CarcinomaRecurrent Fallopian Tube CarcinomaRecurrent Primary Peritoneal Carcinoma+13 more
Mayo Clinic12 enrolled1 locationNCT06483048
Recruiting
Phase 1

A Drug-drug Interaction Study of Vorasidenib and a Combined Oral Contraceptive in Healthy Female Participants

Healthy Adult Female Participants
Institut de Recherches Internationales Servier (I.R.I.S.)28 enrolled1 locationNCT07235774
Recruiting
Phase 1

Talazoparib and Radiation Therapy in Treating Patients With Locally Recurrent Gynecologic Cancers

Malignant Female Reproductive System NeoplasmStage IV Cervical Cancer AJCC v8Stage IVA Cervical Cancer AJCC v8+22 more
M.D. Anderson Cancer Center24 enrolled2 locationsNCT03968406
Recruiting
Phase 1

Pharmacokinetic Comparison of Vonafexor Acid and Its Lysine Salt and Evaluation of Potential Drug-Drug Interactions

Healthy Adult Male and Female Volunteers
Enyo Pharma40 enrolled1 locationNCT07251153
Recruiting
Phase 1

A Study of ORX489 in Healthy Adult Participants, Aged 18 to 60 Years

Healthy Adult Male and Female Volunteers
Centessa Pharmaceuticals (UK) Limited212 enrolled1 locationNCT07413666
Recruiting
Phase 1

Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax

Malignant Solid NeoplasmAnatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8+71 more
M.D. Anderson Cancer Center43 enrolled1 locationNCT05092373
Recruiting
Phase 1

A Comparative Bioavailability Study of Two Torasemide 10 mg Tablets Formulations in Healthy Adult Participants Under Fasting Conditions:

Healthy Adult Male and Female Volunteers
Berlin-Chemie AG Menarini Group26 enrolled1 locationNCT07201584
Recruiting
Phase 1

Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases

Malignant Neoplasm of Bone and Articular CartilageMalignant Neoplasms of Female Genital OrgansMalignant Neoplasms of Independent (Primary) Multiple Sites+7 more
M.D. Anderson Cancer Center44 enrolled1 locationNCT03093909
Recruiting
Phase 1Phase 2

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

Advanced Solid TumorsCarcinomaNeoplasms+9 more
Marengo Therapeutics, Inc.365 enrolled32 locationsNCT05592626
Recruiting
Phase 1

To Evaluate the Effect of Food on the Pharmacokinetics of Y-4 Tablets in Healthy Subjects

Healthy Male and Female Subjects
Beijing Tiantan Hospital20 enrolled1 locationNCT07013773
Recruiting
Phase 1

Validation Study of an Assistive Pulse Data Collection Device

Healthy Male and Female Subjects
The Hong Kong Polytechnic University30 enrolled1 locationNCT06974227
Recruiting
Phase 1

Pharmacokinetics of Y-4 Tablets With Pregabalin Capsules and Riluzole Tablets in Chinese Healthy Subject

Healthy Male and Female Subjects
Beijing Tiantan Hospital10 enrolled1 locationNCT06935721
Recruiting
Phase 1

Safety and Pharmacokinetics of Y-4 Tablets in Healthy Subjects

Healthy Adult Male and Female Volunteers
Beijing Tiantan Hospital36 enrolled1 locationNCT06935682
Recruiting
Phase 1Phase 2

Evaluating Mechanically Engineered Stem Cell Exosomes for Treating Endometrial Injury: A Clinical Study

Female InfertilityThin Endometrial Lining
Tang-Du Hospital90 enrolled2 locationsNCT06896747
Recruiting
Phase 1

Optimal Timing of Euploid Day 6 Blastocyst Transfer in Frozen HRT Cycles, Day 6 or Day 7 of Progesterone Administration.

InfertilityInfertility, FemaleFertility Issues
ART Fertility Clinics LLC316 enrolled2 locationsNCT05980091
Recruiting
Phase 1

Impact of OnabotulinumtoxinA (BOTOX®) on Stress

StressStress (Psychology)Stress, Psychologic+4 more
Center for Advanced Facial Plastic Surgery20 enrolled1 locationNCT06778421
Recruiting
Phase 1

Comparison of Live Birth Rate in Natural Cycle Single Euploid FET Versus Without Luteal Phase Support

Infertility, FemalePregnancy Related
ART Fertility Clinics LLC342 enrolled3 locationsNCT05969795