Phase 2 Female Clinical Trials

33 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 33 trials

Recruiting
Phase 2

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

Anatomic Stage III Breast Cancer AJCC v8Anatomic Stage IV Breast Cancer AJCC v8Malignant Female Reproductive System Neoplasm+12 more
National Cancer Institute (NCI)2,900 enrolled479 locationsNCT05564377
Recruiting
Phase 2

Testing the Use of Neratinib or the Combination of Neratinib and Palbociclib Targeted Treatment for HER2+ Solid Tumors (A ComboMATCH Treatment Trial)

Malignant Solid NeoplasmMalignant Female Reproductive System NeoplasmRecurrent Malignant Solid Neoplasm+1 more
National Cancer Institute (NCI)70 enrolled185 locationsNCT06126276
Recruiting
Phase 2Phase 3

Uterine Transplant in Absolute Uterine Infertility (AUIF)

Female Infertility
Brigham and Women's Hospital10 enrolled1 locationNCT02741102
Recruiting
Phase 2

Vaginal DHEA to Improve Vaginal Health After Radiation for Women With Gynecologic, Anal or Rectal Cancer

Anal CarcinomaCervical CarcinomaVaginal Carcinoma+3 more
Ohio State University Comprehensive Cancer Center25 enrolled1 locationNCT07407647
Recruiting
Phase 1Phase 2

ERADICATE: A Phase Ib/II Study of Elacestrant Plus Trastuzumab Deruxtecan in Patients With CDK4/6 Inhibitor and Endocrine-resistant HR+/HER2-low or HER2-ultralow Metastatic Breast Cancer

Breast CancerMetastatic Breast CancerBreast Cancer Female+2 more
Sarah Sammons, MD65 enrolled1 locationNCT07198724
Recruiting
Phase 2

Microbiome and Association With Implant Infections

Breast CancerBreast Cancer FemaleGenetic Predisposition to Disease
University of California, San Francisco200 enrolled1 locationNCT05020574
Recruiting
Phase 2

Fucoidan for Preventing Chemotherapy-Related Fatigue in Patients With Gastrointestinal or Gynecological Cancer

Malignant Female Reproductive System NeoplasmMalignant Digestive System Neoplasm
Mayo Clinic34 enrolled1 locationNCT06855524
Recruiting
Phase 2Phase 3

Benefit of GnRH Agonist Before Frozen Embryo Transfer in Patients With Endometriosis and/or Adenomyosis

EndometriosisInfertility, FemaleAdenomyosis
Hopital Foch180 enrolled1 locationNCT04356664
Recruiting
Phase 2

Dostarlimab, Cisplatin and Etoposide in Combination With Radiotherapy in Sandwich Sequence for Small Cell Neuroendocrine Cervical Carcinoma

Female
Chang Gung Memorial Hospital45 enrolled1 locationNCT07336147
Recruiting
Phase 2

IIT2023-09-Chung-UpfrontTAD: Upfront TAD/SNB in Patients With Breast Cancer With Nodal Metastases

Breast CancerFemale Breast CancerMastectomy; Lymphedema+3 more
Alice Chung45 enrolled3 locationsNCT06092892
Recruiting
Phase 2

Omission of Local Therapies in Women Patients With HER2-positive or Triple-negative Breast Cancer

Breast Neoplasm Malignant Female
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano152 enrolled1 locationNCT06938724
Recruiting
Phase 2

Stage II-IIIa Urothelial Cancer Randomizing Pre-operative Nivolumab With or Without Relatlimab

NeoplasmsNeoplasms by SiteUrinary Bladder Neoplasm+8 more
The Netherlands Cancer Institute90 enrolled9 locationsNCT06237920
Recruiting
Phase 2

Neoadjuvant Chemotherapy Plus Cadonilimab for Locally Advanced Cervical Cancer

Locally Advanced Cervical CancerFemale, Age ≥ 18 Years OldNo Previous Systemic Treatment for the Current Disease, Including Surgery, Antitumor Radiochemotherapy/Immunotherapy+6 more
The First Affiliated Hospital of Zhengzhou University29 enrolled1 locationNCT07104149
Recruiting
Phase 2

DATO-BASE: DATOpotamab-deruxtecan for Breast Cancer Brain metAstaSEs

Breast CancerBreast Cancer FemaleHER2-negative Breast Cancer+2 more
Sarah Sammons, MD58 enrolled3 locationsNCT06176261
Recruiting
Phase 2

The Breast Cancer Survivors and Partners Online Research Together (SUPORT) Project

Breast Cancer FemalePsychological Distress
University of Arizona452 enrolled1 locationNCT05676255
Recruiting
Phase 2

Phase II Trial of Disulfiram With Copper in Metastatic Breast Cancer

Metastatic Breast CancerBreast Neoplasm Female
The Institute of Molecular and Translational Medicine, Czech Republic150 enrolled1 locationNCT03323346
Recruiting
Phase 1Phase 2

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

Advanced Solid TumorsCarcinomaNeoplasms+9 more
Marengo Therapeutics, Inc.365 enrolled32 locationsNCT05592626
Recruiting
Phase 2

The SAPPHO Study: Sequential Therapy With Curative Intent in de Novo HER2+ Metastatic Breast Cancer

Breast CancerBreast Cancer MetastaticBreast Cancer Female+3 more
Dana-Farber Cancer Institute72 enrolled1 locationNCT06439693
Recruiting
Phase 2

Convergent Mechanisms Underlying Reprometabolic Syndrome in Women

ObesityInfertility, Female
University of Colorado, Denver20 enrolled2 locationsNCT06686537
Recruiting
Phase 1Phase 2

Evaluating Mechanically Engineered Stem Cell Exosomes for Treating Endometrial Injury: A Clinical Study

Female InfertilityThin Endometrial Lining
Tang-Du Hospital90 enrolled2 locationsNCT06896747