Fibrillation Clinical Trials

1 recruitingLast updated: May 5, 2026

There are 518 actively recruiting fibrillation clinical trials across 68 countries. Studies span Not Applicable, Phase 4, Phase 3, Phase 2, Phase 1, Early Phase 1. Top locations include New York, New York, United States, Beijing, Beijing Municipality, China, Ottawa, Ontario, Canada. Updated daily from ClinicalTrials.gov.


Fibrillation Trials at a Glance

518 actively recruiting trials for fibrillation are listed on ClinicalTrialsFinder across 6 cities in 68 countries. The largest study group is Not Applicable with 254 trials, with the heaviest enrollment activity in New York, Beijing, and Ottawa. Lead sponsors running fibrillation studies include Beijing Anzhen Hospital, Boston Scientific Corporation, and Ottawa Heart Institute Research Corporation.

Browse fibrillation trials by phase

Treatments under study

About Fibrillation Clinical Trials

Looking for clinical trials for Fibrillation? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Fibrillation trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Fibrillation clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 518 trials

Recruiting
Not Applicable

PVI Alone vs PVI and Linear Ablation for Persistent Atrial Fibrillation (PROMPT AF II)

Persistent Atrial Fibrillation
Boston Scientific Corporation640 enrolled1 locationNCT07106970
Recruiting
Not Applicable

Applause Study I - Append System Early Feasibility Study

Non Valvular Atrial Fibrillation
Append Medical Ltd.15 enrolled1 locationNCT07278869
Recruiting
Not Applicable

Feasibility Study of the FARAFLEX Mapping and PFA System

Atrial FibrillationPersistent Atrial FibrillationParoxysmal AF
Boston Scientific Corporation250 enrolled4 locationsNCT06510556
Recruiting
Not Applicable

Pill-in-the-POCKET Oral Anticoagulation Strategy After AF Catheter Ablation

Atrial Fibrillation
Seoul National University Hospital400 enrolled1 locationNCT06216769
Recruiting
Not Applicable

Cryoballoon/Radiofrequency/Pulsed Field Ablation of Atrial Fibrillation Versus Medical Treatment for Heart

Atrial Fibrillation (AF)
University College, London1,200 enrolled24 locationsNCT06505798
Recruiting
Not Applicable

Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation Therapy

Atrial FibrillationIschemic Stroke
Insel Gruppe AG, University Hospital Bern482 enrolled28 locationsNCT05976685
Recruiting
Not Applicable

Optimizing Quality of Life by Improved Patient Expectation Following Atrial Fibrillation Catheter Ablation

Atrial Fibrillation
Evangelical Hospital Düsseldorf60 enrolled2 locationsNCT05557526
Recruiting

REGistry of Long-term AnTithrombotic TherApy-2

Atrial Fibrillation
National Medical Research Center for Cardiology, Ministry of Health of Russian Federation2,000 enrolled1 locationNCT04347187
Recruiting
Phase 1Phase 2

Anthocyanin-Rich Table Grape Powder for Prophylaxis of Post-Operative Atrial Fibrillation

Post-operative Atrial Fibrillation (POAF)
University of Michigan70 enrolled1 locationNCT05991700
Recruiting
Not Applicable

Randomized Controlled Trial- Ablation Strategy for Paroxysmal Atrial Fibrillation - Trigger and Substrate Guided Wide Area Radiofrequency Ablation Compared to Pulsed Field Ablation Pulmonary Vein Isolation

Atrial FibrillationCatheter AblationRadiofrequency Catheter Ablation
Ottawa Heart Institute Research Corporation556 enrolled2 locationsNCT04823299
Recruiting
Phase 3

Stroke and Systemic Embolism Prevention in Adult Participants With Atrial Fibrillation for Whom Oral Anticoagulation is Unsuitable

Atrial Fibrillation (AF)
Regeneron Pharmaceuticals2,628 enrolled5 locationsNCT07430956
Recruiting
Not Applicable

SCAR Burden of Left Atrium Guided cathEter Ablation sTrategy for Persistent Atrial Fibrillation

Atrial Fibrillation
Seoul National University Hospital204 enrolled1 locationNCT05794386
Recruiting
Not Applicable

Left Bundle Branch Area Pacing (LBBAP) PMCF Study

Heart FailureCardiac DiseaseAtrial Fibrillation (AF)+4 more
Abbott Medical Devices200 enrolled13 locationsNCT07217392
Recruiting
Phase 2

Safety in Adult Participants With Atrial Fibrillation Who Are Treated With Anticoagulation

Atrial Fibrillation (AF)
Regeneron Pharmaceuticals1,200 enrolled42 locationsNCT07175428
Recruiting
Not Applicable

To Compare and Evaluate the Efficacy and Safety Between TS-RF System and BRK Transseptal Needles Used for Transseptal Puncture for Left Atrial Access.

Atrial FibrillationArrhythmias, CardiacHeart Diseases
Starmed70 enrolled1 locationNCT06358391
Recruiting

PROSPective Evaluation of Outcome After CatheTer Ablation in Atrial Fibrillation

Atrial Fibrillation
University Hospital, Lille750 enrolled1 locationNCT05009797
Recruiting

Atrial Functional Mitral Regurgitation and Tricuspid Regurgitation

Atrial FibrillationFunctional Mitral RegurgitationFunctional Tricuspid Regurgitation
Barts & The London NHS Trust141 enrolled1 locationNCT05920824
Recruiting
Not Applicable

A Study of VARIPULSE Pulsed Field Ablation (PFA) Catheter and FARAWAVE PFA Catheter in the Treatment of Participants With Persistent Atrial Fibrillation

Atrial Fibrillation
Biosense Webster, Inc.466 enrolled1 locationNCT07523750
Recruiting
Phase 4

COmparison of Bleeding Risk Between Rivaroxaban and Apixaban in Patients With Atrial Fibrillation

Atrial Fibrillation
Ottawa Hospital Research Institute3,018 enrolled8 locationsNCT04642430
Recruiting

Biological Bank for Atrial Fibrillation and Stroke

Atrial FibrillationStroke
Hospices Civils de Lyon1,000 enrolled5 locationsNCT03611816