Early Phase 1 Fibrosis Clinical Trials
13 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–13 of 13 trials
Recruiting
Early Phase 1
Hyperbaric Oxygen Therapy and Allogeneic Peripheral Blood Stem Cell (PBSC) Transplant
Acute Myeloid LeukemiaMyelodysplastic SyndromesChronic Myelomonocytic Leukemia+4 more
Omar Aljitawi24 enrolled1 locationNCT03964506
Recruiting
Early Phase 1
Combination of Tagraxofusp With Pacritinib in Patients With Intermediate-1 or Higher Myelofibrosis, Who Have Had Prior Therapy With the Approved JAK Inhibitors or in Which Therapy With the Approved JAK Inhibitors is Not Appropriate, Contraindicated or Declined
Myelofibrosis (MF)
University of Kansas Medical Center20 enrolled1 locationNCT06414681
Recruiting
Early Phase 1
Proof of Principle Study for an Efficacy Trial of Linaclotide for Cystic Fibrosis
Cystic Fibrosis (CF)
University of Nottingham26 enrolled1 locationNCT07569419
Recruiting
Early Phase 1
Hormonal Responses to a Mixed Meal in People With Cystic Fibrosis
Cystic Fibrosis
University of Cincinnati61 enrolled1 locationNCT06163482
Recruiting
Early Phase 1
A Clinical Study to Evaluate Safety, Tolerability and Pharmacokinetics of SV001 in Chinese Healthy Adult Volunteers.
Idiopathic Pulmonary Fibrosis
Shanghai Synvida Biotechnology Co.,Ltd.53 enrolled1 locationNCT06267183
Recruiting
Early Phase 1
68Ga-FAPI-46 PET/CT for Assessing Small Bowel Fibrostenosis in Crohn's Disease
Crohn's DiseaseIntestinal FibrosisInflamatory Bowel Disease+1 more
Mayo Clinic45 enrolled1 locationNCT07273188
Recruiting
Early Phase 1
Personalized Theratyping Trial
Cystic Fibrosis
George Solomon20 enrolled1 locationNCT03587961
Recruiting
Early Phase 1
Regional Monitoring of CF Lung Disease
Cystic Fibrosis
Children's Hospital Medical Center, Cincinnati60 enrolled1 locationNCT06339593
Recruiting
Early Phase 1
Darzalex Faspro (Daratumumab and Hyaluronidase-fihj) Before Standard Desensitization and Allogeneic Peripheral Blood Stem Cell Transplantation in Adult Patients at High-risk for Primary Graft Failure Secondary to Donor Specific Antibodies
Chronic Myeloid LeukemiaHodgkin LymphomaNon-Hodgkin Lymphoma+9 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins8 enrolled1 locationNCT06398457
Recruiting
Early Phase 1
Hyperpolarized Xenon-129 MRI in Idiopathic Pulmonary Fibrosis
Idiopathic Pulmonary Fibrosis
University of Virginia6 enrolled1 locationNCT06853145
Recruiting
Early Phase 1
FAPI PET for Lung Fibrosis
PneumoconiosisRadiation PneumonitisInterstitial Lung Disease+4 more
University of California, Los Angeles30 enrolled1 locationNCT05365802
Recruiting
Early Phase 1
Inhaled Nitric Oxide (iNO) in Idiopathic Pulmonary Fibrosis (IPF).
Idiopathic Pulmonary Fibrosis
Dr. Denis O'Donnell40 enrolled1 locationNCT05052229
Completed
Early Phase 1
A Single Microdose Study to Evaluate the Pharmacokinetics of INS018_055 in Healthy Participants
Idiopathic Pulmonary Fibrosis (IPF)
Insilico Medicine Hong Kong Limited8 enrolled1 locationACTRN12621001541897