Fibrosis Clinical Trials

503 recruitingLast updated: July 11, 2026

There are 503 actively recruiting fibrosis clinical trials across 70 countries. Studies span Phase 2, Not Applicable, Phase 1, Phase 3, Phase 4, Early Phase 1. Top locations include Boston, Massachusetts, United States, New York, New York, United States, Birmingham, Alabama, United States. Updated daily from ClinicalTrials.gov.


Fibrosis Trials at a Glance

503 actively recruiting trials for fibrosis are listed on ClinicalTrialsFinder across 6 cities in 70 countries. The largest study group is Phase 2 with 105 trials, with the heaviest enrollment activity in Boston, New York, and Birmingham. Lead sponsors running fibrosis studies include Hospices Civils de Lyon, Assistance Publique - Hôpitaux de Paris, and Massachusetts General Hospital.

Treatments under study

About Fibrosis Clinical Trials

Looking for clinical trials for Fibrosis? There are currently 13 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Fibrosis trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Fibrosis clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 503 trials

Recruiting

Natural History of Bronchiectasis

Cystic FibrosisBronchiectasisAutoimmune Disease+1 more
National Heart, Lung, and Blood Institute (NHLBI)900 enrolled1 locationNCT00943514
Recruiting

Role of Genetic Factors in the Development of Lung Disease

AsthmaCystic FibrosisPulmonary Fibrosis+2 more
National Heart, Lung, and Blood Institute (NHLBI)3,500 enrolled2 locationsNCT00001532
Recruiting
Phase 3

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

Metabolic dysfunction-associated steatohepatitis (MASH)Liver Fibrosis
Boehringer Ingelheim1,800 enrolled525 locationsNCT06632444
Recruiting
Phase 2

Phase 2 Study to Assess the Safety and Efficacy of ANG003

Cystic Fibrosis (CF)Exocrine Pancreatic Insufficiency (EPI)
Anagram Therapeutics, Inc.113 enrolled26 locationsNCT07450547
Recruiting

Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children

Cystic Fibrosis
Sonya Heltshe210 enrolled35 locationsNCT04509050
Recruiting
Phase 4

Standardizing Treatments for Pulmonary Exacerbations - Aminoglycoside Study

Cystic FibrosisCystic Fibrosis Pulmonary Exacerbation
Chris Goss730 enrolled60 locationsNCT05548283
Recruiting
Phase 1

A Vaccine (CMV-MVA Triplex Vaccine) for the Enhancement of CMV-Specific Immunity and the Prevention of CMV Viremia in Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplant

Hematopoietic and Lymphatic System NeoplasmAcute Lymphoblastic LeukemiaAcute Myeloid Leukemia+9 more
City of Hope Medical Center46 enrolled3 locationsNCT07020533
Recruiting
Phase 1

Clinical Study of CFH Protein Via Ice Microneedles for Radiation-Induced Skin Fibrosis

Head and Neck Squamous Cell CarcinomaRadiation-Induced Skin Fibrosis
West China Hospital9 enrolled1 locationNCT07567235
Recruiting
Not Applicable

Long-term Evaluation of the SIMEOX Device at Home in Non-cystic Fibrosis Bronchiectasis

Non-cystic Fibrosis Bronchiectasis
Physio-Assist622 enrolled57 locationsNCT06487273
Recruiting
Phase 1

A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease

Chronic Obstructive Pulmonary DiseaseNon-cystic Fibrosis Bronchiectasis
Genentech, Inc.128 enrolled7 locationsNCT06603246
Recruiting
Phase 2

Allo HSCT Using RIC and PTCy for Hematological Diseases

Acute Myelogenous LeukemiaMyelodysplastic SyndromesLeukemia, Myeloid+15 more
Masonic Cancer Center, University of Minnesota56 enrolled1 locationNCT05805605
Recruiting

Study to Enable New Diagnostics for Pulmonary Microbes in People With CF

Cystic Fibrosis (CF)New Diagnostics
Chris Goss300 enrolled9 locationsNCT07312734
Recruiting
Phase 3

A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)

Primary myelofibrosis (PMF)Post-polycythemia Vera Myelofibrosis (PPV-MF)Post-essential Thrombocythemia Myelofibrosis (PET-MF)
Novartis Pharmaceuticals460 enrolled20 locationsNCT07357727
Recruiting

TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

Cystic Fibrosis (CF)
State University of New York at Buffalo600 enrolled13 locationsNCT07048574
Recruiting
Not Applicable

Gastrointestinal Response of Pediatric Cystic Fibrosis Patients on Mediterranean Diet

Cystic Fibrosis (CF)Cystic Fibrosis Gastrointestinal Disease
Dartmouth-Hitchcock Medical Center20 enrolled2 locationsNCT07223255
Recruiting
Phase 2

A Phase 2 Study of LTI-03 in Patients With Idiopathic Pulmonary Fibrosis

Idiopathic Pulmonary Fibrosis (IPF)
Rein Therapeutics120 enrolled21 locationsNCT06968845
Recruiting
Phase 2

An Extension Study of Subjects Who Received an Avalyn Inhaled Antifibrotic Agent (SAIL)

Progressive Pulmonary FibrosisIdiopathic Pulmonary Fibrosis (IPF)
Avalyn Pharma Inc.340 enrolled54 locationsNCT06951217
Recruiting
Phase 2

4D-710 in Adult Patients With Cystic Fibrosis

Cystic Fibrosis Lung
4D Molecular Therapeutics30 enrolled20 locationsNCT05248230
Recruiting
Not Applicable

ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2

Type 1 DiabetesType 2 DiabetesCystic Fibrosis-related Diabetes
Johns Hopkins University500 enrolled1 locationNCT05463289
Recruiting
Not Applicable

Optimizing the Diagnostic Journey in Interstitial Lung Disease: The OPTIMIZE-ILD-1 Trial

Fibrotic interstitial lung diseaseInterstitial Lung Disease (ILD)Idiopathic Pulmonary Fibrosis (IPF)+2 more
Hospital de Granollers92 enrolled1 locationNCT07482917